Streptomyces noursei NK660: DC74_5432
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Entry
DC74_5432 CDS
T03082
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
salu
Streptomyces noursei NK660
Pathway
salu00020
Citrate cycle (TCA cycle)
salu00630
Glyoxylate and dicarboxylate metabolism
salu00785
Lipoic acid metabolism
salu01100
Metabolic pathways
salu01110
Biosynthesis of secondary metabolites
salu01120
Microbial metabolism in diverse environments
salu01200
Carbon metabolism
salu01210
2-Oxocarboxylic acid metabolism
Module
salu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
salu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
salu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
DC74_5432
00630 Glyoxylate and dicarboxylate metabolism
DC74_5432
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DC74_5432
Enzymes [BR:
salu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
DC74_5432
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
DC74_5432
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
DC74_5432
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
DC74_5432
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
Motif
Other DBs
NCBI-ProteinID:
AIA05892
LinkDB
All DBs
Position
complement(6145063..6148530)
Genome browser
AA seq
1155 aa
AA seq
DB search
MKPAASAAPAPAKPAAKPAPAAKQPAASNGAAPEGPELVTLRGPSAAVAKNMSASLELPT
ATSVRAVPVKLLFDNRIVINNHLKRARGGKVSFTHVIGYAMVQALKAMPSMNNSFAEKDG
KPTLVKPPHINLGLAIDLVKAKGERQLVVAAIKKAETLSFFEFWQAYEDIVRRARDNKLT
MDDFTGVTASLTNPGGIGTVHSVPRLMPGQSMIMGVGSMDYPAEFQGTSQDALNKLGVSK
VMTLTSTYDHRVIQGAASGEFLRIMSQLLLGENDFYDDIFKSLRIPYEPIRWMRDIDASH
DDDVTKAARVFELIHSYRQRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGG
FAGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHKSPERDEQLRIL
RRLNSAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEAVIGMAHRGRL
NVLANIVGKSYAQLFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQITVSLAANPS
HLEAVDPIVEGIARAKQDIINKGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQLRGYRT
GGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFR
QAFNKDVVIDLICYRRRGHNELDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEE
AEQALQDFQGQLEKVFTEVRDATTTPATPEVPLPQAEFPVHVETAVSQEVVKRIAESQVN
IPDNITVHPRLLPQLQRRATMVEEGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFG
QRHAVLIDRETGGDYTPLLYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPDALVMWEA
QFGDFTNGAQTVIDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQN
NMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAAEFTTGGFRPVIG
DAAVKPEDVRKVVFCSGKVYYDLEEERIKRGAFDTALVRIERLYPLPGKELQAEIAKFPN
AEKYLWAQEEPANQGAWPFLGLNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKR
HQAEQAQLVAEVFDA
NT seq
3468 nt
NT seq
+upstream
nt +downstream
nt
gtgaagcccgctgccagcgccgcgccggcgcccgctaagcccgcggcgaagccggccccg
gcggccaagcagcccgccgcgagcaacggcgcggcgcccgagggccccgagctggtgacc
ctgcgcggcccgtccgcggccgtggcgaagaacatgagcgcgtccctggagctgccgacg
gccacgtccgtccgtgcggtcccggtgaagctgctgttcgacaaccggatcgtcatcaac
aaccacctcaagcgcgcccgcggcgggaaggtctccttcacgcacgtcatcgggtacgcg
atggtgcaggccctcaaggccatgccgtcgatgaacaactccttcgcggagaaggacggc
aagccgaccctggtcaagccgccgcacatcaacctcggcctggccatcgacctggtcaag
gcgaagggcgagcgccagctggtcgtcgcggccatcaagaaggccgagacgctgagcttc
ttcgagttctggcaggcgtacgaggacatcgtccgccgggcccgggacaacaagctcacg
atggacgacttcaccggggtcaccgcgtcgctgaccaaccccggcggcatcggcaccgtc
cactcggtgccgcgcctgatgcccggccagtcgatgatcatgggcgtcggctcgatggac
tacccggccgagttccagggcacctcgcaggacgccctgaacaagctgggcgtctccaag
gtcatgacgctgaccagcacctatgaccaccgggtgatccagggcgccgcctccggcgag
ttcctgcggatcatgagccagctgctgctcggcgagaacgacttctacgacgacatcttc
aagtcgctgcggatcccctacgagccgatccgctggatgcgcgacatcgacgcgtcgcac
gacgacgacgtcaccaaggccgcgcgggtcttcgagctgatccactcctaccggcagcgc
ggccacgtcatggccgacaccgacccgctggagtaccaccagcgcaagcaccccgacctg
gacatcaccgagcacggcctcaccctgtgggacctggagcgggagttcgcggtcggtggc
ttcgccggcaagtcgatgatgaagctgcgcgacatcctgggcgtgctgcgcgactcgtac
tgccgcaccaccggcatcgagttcatgcacatccaggaccccaagcagcgcaagtggatc
caggaccgggtcgagcgcccgcacaagtcgcccgagcgcgacgagcagctgcgcatcctg
cgccggctgaactccgccgaggcgttcgagacgttcctgcagaccaagtacgtcggccag
aagcgcttctccctggagggcggcgaatcggtcatcccgctgctggacgcggtcatcgac
tccgcggccgaggcgcggctggacgaggccgtcatcggcatggcccaccgcggccggctc
aacgtgctggcgaacatcgtcggcaagtcctacgcgcagctcttccgcgagttcgagggc
aacctcgacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgag
ggcaccttcaccggcctggacggcgagcagatcaccgtctcgctggccgcgaacccctcc
cacctggaggccgtcgacccgatcgtcgagggcatcgcccgcgccaagcaggacatcatc
aacaagggcggcacggacttcacggtcctgccgatccagctgcacggtgacgcggcgttc
gccggtcagggcgtggtcgcggagacgctgaacatgtcccagctgcgcggctaccgcacc
ggcggcacggtgcacgtggtcatcaacaaccaggtcggcttcaccgccgcgccggagtcc
tcgcgctcctccatgtacgccaccgacgtggcccgcatgatcgaggcgccgatcttccac
gtgaacggcgacgaccccgaggccgtcgtccgggtcgcccggctcgccttcgagttccgc
caggcgttcaacaaggacgtggtcatcgacctcatctgctaccgccgccgcggccacaac
gagctggacaacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgc
tcggtgcgcaagctctacaccgagtcgctgatcggccggggcgacatcaccctcgaagag
gcggagcaggcgctccaggacttccagggccagctggagaaggtcttcaccgaggtccgc
gacgccaccaccacgccggccacgcccgaggtgccgctgccgcaggcggagttcccggtg
cacgtggagaccgcggtctcccaggaggtcgtcaagcggatcgccgagtcccaggtcaac
atccccgacaacatcaccgtccacccgcggctgctgccccagctgcagcgccgggcgacg
atggtcgaggaaggcaccatcgactggggcatgggcgagaccctggccatcggttcgctg
ctgatggagggcaccccggtccggctcgccggccaggactcccgccgcggcacgttcggc
cagcgccacgcggtgctgatcgaccgggagaccggcggggactacaccccgctgctgtac
ctgtccgaggaccaggcccgcttcaacgtctacgactcgctgctcagcgagtacgcggcg
atgggcttcgagtacggctactcgctggcccgtccggacgcgctggtgatgtgggaggcg
cagttcggtgacttcaccaacggcgcgcagaccgtcatcgacgagttcatctcgtccgcg
gagcagaagtggggccagacctccggcgtcaccctgctgctcccgcacggctacgagggc
cagggcccggaccactcctcggcccggatcgagcgcttcctccagctgtgcgcgcagaac
aacatgaccgtcgcgatgccgacgctcccgtcgaactacttccacctgctgcgctggcag
gtgcacaacccgcaccacaagccgctggtcgtcttcaccccgaagtcgatgctgcgtctg
aaggccgcggcgtcgaaggcggcggagttcaccaccggcggcttccgtccggtcatcggc
gacgccgcggtcaagcccgaggacgtccgcaaggtcgtcttctgctccggcaaggtctac
tacgacctggaggaggagcggatcaagcgcggcgcgttcgacaccgcgctggtccggatc
gagcggctgtacccgctgcccggcaaggagctccaggcggagatcgccaagttcccgaac
gccgagaagtacctgtgggcgcaggaggagccggcgaaccagggtgcctggccgttcctc
ggtctgaacctgatcgaccacctggacctggcggtcggcgccgacgtcccgcacggtgag
cgcctgcgccgcatctcgcggccgcacggctcgtcgccggcggtcggctcggccaagcgg
caccaggccgagcaggcccagctggtggccgaggtcttcgacgcgtga
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