Streptomyces noursei NK660: DC74_6590
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Entry
DC74_6590 CDS
T03082
Name
(GenBank) beta-ketoacyl synthase
KO
K05551
minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
salu
Streptomyces noursei NK660
Pathway
salu00253
Tetracycline biosynthesis
salu01056
Biosynthesis of type II polyketide backbone
salu01100
Metabolic pathways
salu01110
Biosynthesis of secondary metabolites
Module
salu_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
salu00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
DC74_6590
00253 Tetracycline biosynthesis
DC74_6590
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
salu01004
]
DC74_6590
01008 Polyketide biosynthesis proteins [BR:
salu01008
]
DC74_6590
Enzymes [BR:
salu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
DC74_6590
2.3.1.260 tetracycline polyketide synthase
DC74_6590
Lipid biosynthesis proteins [BR:
salu01004
]
Polyketide synthase
Component type
DC74_6590
Polyketide biosynthesis proteins [BR:
salu01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
DC74_6590
Nonaketide PKS
DC74_6590
Decaketide PKS
DC74_6590
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
AIA07024
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All DBs
Position
7522025..7523296
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AA seq
423 aa
AA seq
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MTARRVVITGIGVLAPGGIGTKDFWSLLSEGRTATQAITLFDPAPFRSRVAAQAAFDPEE
HGLGPQEVRRMDRAAQFAVVTARQALTDSGLDRSEHPPHRIGVTLGSAVGASMTLDQEYR
VVSDGGRLEHVSHAYAPRHLYNAFVPSSFAAETAWAVAAEGPTTVVSTGCTSGIDAVGHA
VELIRDGSADVMVAGATDAPISPITLACFDAIKATTPRNDDPAHASRPFDGTRNGFVLGE
GAALFVLEELQAARRRGAHIYAEIAGYAQRCNAFHMTGLRPDGAEMATAIDAALAEARTH
PSDIDYVSAHGSGTKQNDRHETAALKKSLGDHAYRVPVSSIKSMVGHSLGAIGSIEIAAC
ALAMENHVVPPTANLHTPDPECDLDYVPLTARDWRTDTVLTVGSGFGGFQSAMVLTRPGR
NAA
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcccgccgcgtcgtcatcaccggcatcggcgtcctcgccccgggcggcatcggc
accaaggacttctggagcctgctcagcgagggccgcaccgccacccaggccatcaccctc
ttcgaccccgcccccttccgctcgcgggtcgccgcccaagccgccttcgaccccgaagaa
cacggcctcggcccgcaggaagtccgtcggatggaccgcgccgcccagttcgccgtcgtc
accgcccgacaggccctcaccgacagcggcctggaccgaagcgagcaccccccgcaccgc
atcggcgtcaccctcggcagcgcggtcggcgcctccatgacgctggaccaggagtaccgc
gtcgtcagcgacggcgggcgcctggaacacgtcagccacgcgtacgcgccccgccacctc
tacaacgcgttcgtgcccagctcgttcgccgccgagaccgcctgggcggtggccgccgag
ggccccaccaccgtcgtctccaccggctgcacctccggcatcgacgccgtcggccacgcc
gtcgaactcatccgggacggctccgccgacgtgatggtcgccggcgccaccgacgccccc
atctcccccatcacgctggcctgcttcgacgccatcaaggccaccacgccccgcaacgac
gaccccgcgcacgcctcccggcccttcgacggcacccgcaacggcttcgtcctgggcgaa
ggcgccgccctcttcgtgctcgaagaactccaggcggcccgccggcgcggcgcccacatc
tacgccgagatcgccggctacgcccaacgctgcaacgccttccacatgacgggcctgcgc
cccgacggcgccgaaatggccaccgccatcgacgccgccctcgccgaggcccgcacccac
cccagcgacatcgactacgtcagcgcccacggctccggcaccaagcagaacgaccgccac
gagaccgccgccctgaagaagagcctcggcgaccacgcctaccgcgtccccgtcagctcc
atcaagtcgatggtcggccactcgctgggcgccatcggctccatcgagatcgccgcctgt
gccctggccatggagaaccacgtcgtgccccccaccgccaacctccacacccccgacccc
gagtgcgacctggactacgtcccgctgaccgcgcgcgactggcgcaccgacaccgtgttg
accgtgggcagcggcttcggcgggttccagagcgccatggtgctgacccggcccggaagg
aacgccgcgtga
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