Streptomyces ambofaciens: SAM23877_2278
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Entry
SAM23877_2278 CDS
T04055
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
samb
Streptomyces ambofaciens
Pathway
samb00010
Glycolysis / Gluconeogenesis
samb00020
Citrate cycle (TCA cycle)
samb00620
Pyruvate metabolism
samb00785
Lipoic acid metabolism
samb01100
Metabolic pathways
samb01110
Biosynthesis of secondary metabolites
samb01120
Microbial metabolism in diverse environments
samb01200
Carbon metabolism
samb01210
2-Oxocarboxylic acid metabolism
Module
samb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
samb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SAM23877_2278 (aceE)
00020 Citrate cycle (TCA cycle)
SAM23877_2278 (aceE)
00620 Pyruvate metabolism
SAM23877_2278 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SAM23877_2278 (aceE)
Enzymes [BR:
samb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SAM23877_2278 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AKZ55327
UniProt:
A0A0K2AR78
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Position
2375977..2378679
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AA seq
900 aa
AA seq
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MTDPKAIQPSELDQLPDRDPEETAEWQASLDAVTQAAGPHRAAYLMRRTLERAEGAGLAL
PKLLETDYVNSIPTADEPSVDGDEDLEQRITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFKGKEGDGSGDQLYIQGHASPGIYARAFLDGRLTEEHLDNFRREAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPISAIYQARFNRYLTSRGIKDLTNSHVWAFLGDGEM
DEPESTTALTLASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSL
WGTAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALVEMAKLLSD
DKILECFHYSRGGHESRKVYAAYRAALAHKGAPTVILAQTVKGHTLGTGFASKNANHQMK
KLSVDEFKAMRDLLGLPIKDSDFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
PVAPLPAPAEKAFASFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTSYAT
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPA
IAATNPAALTYDPAFAYEVAAIVKDGLRRMYGEAAPGEDPDVFYYLTVYNEPMPQPAKPS
APGVDEGIVKGLYRFNTAESAGLTPAANAPRIQLLGSGTAIHWALKAQRLLAEEWGVASD
VWSATSWTELRRDALDADAALLRGEERVPYVRRALQGVEGPVLAVSDYMRQVPDQIAQWV
EQDWSSLGADGFGLSDTREAARRHFGVDAESIVVASLAQLARRGEVKATAVKEARERYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaaagccatccagccgagcgagctcgaccagctcccggaccgcgacccg
gaggagaccgccgaatggcaggcctccctggacgccgtcacccaggcggccgggccgcac
cgtgccgcgtacctgatgcgccgcacactggagcgcgccgagggcgccggcctcgccctg
ccgaagctcctggagacggactacgtcaactccatcccgaccgccgacgagcccagcgtg
gacggcgacgaggacctggagcagcggatcaccgcctggaaccgctggaacgcggcggcg
atggtcacccgcggcagcaagtacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctgtacgagaccggcttcaaccacttcttcaagggcaaggagggtgacgggtcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggctgaccgaggagcacctcgacaacttccgccgcgaggccggcggcaacggc
ctgccgtcctacccgcacccgcgccggctgccgtggctgtgggagttccccaccgtctcc
atgggcctcggcccgatctccgcgatctaccaggcgcggttcaaccgctacctgaccagc
cgcggcatcaaggacctgacgaactcccacgtgtgggcgttcctcggcgacggcgagatg
gacgagccggagtccaccaccgcgctgaccctcgcctcccgcgagggcctggacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggtccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtgaagtcgctg
tggggcacggcgtgggacgagctgttccagctcgacaccaccggcgcgctcgtacgccgc
ctgcgcgaggtacccgacgcgcaggtgcagacgtaccagacgcgcgacgccgcctacatc
cgcgaggacttcttcggcaaggacccggcgctcgtcgagatggcgaagctgctgtccgac
gacaagatcctcgagtgcttccactactcgcgcggcggccacgagtcccgcaaggtctac
gccgcctaccgcgccgcgctcgcccacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggcaccggcttcgcgtccaagaacgccaaccaccagatgaag
aagctctcggtggacgagttcaaggccatgcgcgacctgctcggcctgccgatcaaggac
agcgacttcgtcgacggcgtggtcccctacggccacccgggcgccgactcccccgaggtc
cgttacctccaggagcggcgcgccgccctcggcggtccggccccggcccgccgcgtccac
ccggtcgccccgctgcccgcgcccgccgagaaggccttcgcctccttcgacaagggctcc
ggttcgcagaacgtggccaccaccatggccttcgtccgcctggtcaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgtaccttcggc
atggagagcctcttcccgtccctgggcatctactcgcccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccaagaacggccagatcctcaacgag
gggatcaccgaggccggctcgatggccgacttcatcgccgcttcgacgtcgtacgcgacg
cacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctggtcggcgccacc
gccggccggaccacgctgaccggtgagggcctccagcacgcggacggccactccccggcc
atcgcggcgaccaacccggccgccctgacgtacgacccggcgttcgcgtacgaggtcgcg
gcgatcgtcaaggacggtctgcgccggatgtacggcgaggcggctccgggtgaggacccg
gacgtcttctactacctcaccgtctacaacgagccgatgccgcagccggccaagccgtcc
gcgcccggcgtggacgagggcatcgtcaagggcctgtaccgcttcaacacggcggagtcc
gcgggcctgaccccggccgccaacgccccgcgcatccagctgctgggctccggcacggcg
atccactgggcgctgaaggcgcagcggctgctcgccgaggagtggggcgtggcctccgac
gtgtggtccgcgacctcctggacggagctgcgccgcgacgcgctggacgccgacgcggca
ctgctgcgcggcgaggagcgggtgccgtacgtccgccgggcgctccagggcgtcgagggg
ccggtcctcgcggtgtccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactggtcctcgctgggcgccgacggcttcggcctgtcggacacccgtgaggcc
gcccgccgccacttcggcgtcgacgccgagtccatcgtggtcgcgtccctcgcccagctc
gccaggcgtggcgaggtcaaggcgacggccgtgaaggaggcgcgcgagcgctacggtctg
tag
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