Streptomyces anulatus: KZO11_08450
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Entry
KZO11_08450 CDS
T09280
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sanl
Streptomyces anulatus
Pathway
sanl00010
Glycolysis / Gluconeogenesis
sanl00020
Citrate cycle (TCA cycle)
sanl00620
Pyruvate metabolism
sanl00785
Lipoic acid metabolism
sanl01100
Metabolic pathways
sanl01110
Biosynthesis of secondary metabolites
sanl01120
Microbial metabolism in diverse environments
sanl01200
Carbon metabolism
sanl01210
2-Oxocarboxylic acid metabolism
Module
sanl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sanl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KZO11_08450 (aceE)
00020 Citrate cycle (TCA cycle)
KZO11_08450 (aceE)
00620 Pyruvate metabolism
KZO11_08450 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KZO11_08450 (aceE)
Enzymes [BR:
sanl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KZO11_08450 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QYA93744
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Position
1929975..1932644
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AA seq
889 aa
AA seq
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MTDPVGKLPSELDQLPDRDPEETAEWAASLDAVTQAAGPHRAAYLMRRSLQHAEGAGLAL
PKLLETDYVNTIPTAAEPAFDGDLEMESRITAWNRWNAAAMVTRGARYGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLNEQQLDNFRQESGGEG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLANRNIKDTANSHVWAFLGDGEM
DEPESTAALALASREQLDNLTFVINCNLQRLDGPVRANFRVVQELEAQFRGAGWNVVKTL
WGNAWDELFQLDTQGALLRRLREVPDAQFQTYATRDVAYIREHFFGTEPALVELAKLLTD
AKIGECFYTSRGGHEARKVYAAYRAAVEHKGAPTVILAQTVKGYTLGKGFESKNANHQMK
KLSIDEFKGMRELLGLPIPDSAFEDGLVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
AVALPQPEERAFKALYKGSGKQEMATTMAFVRLVKDLMRDKETGKRWVPIVPDEARTFGM
ESLFPSAGIYSPLGQTYDPVDRDQLMYYKEAKDGQILNEGITEAGSMADFIAASTSYATH
GETMIPFYIFYSMFGWQRTGDQMWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHLI
AATNPASLNYDPAFAYEVAVIVKDGLRRMYGPEAENVFYYLTVYNEPKPQPAMPEGVEEG
IVKGLYRFKEGTPAKADAPRLQLLASGTAIHWALEAQELLAADWGVTADVWSATSWGELR
RDALEADEALLRGEQQVPYVTQALSGAPGPVLAVSDWMRQVPDQISQWVEQDWSSLGTDG
FGLSDTRAAARRHFGVDAQSIVVASLAQLARRGEVPASAIKEARERYGL
NT seq
2670 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccgtaggaaagcttccgagcgagctcgaccagctcccggaccgtgacccc
gaggagaccgccgaatgggcggcctccctggacgccgtcacccaggccgccggcccgcac
cgtgccgcgtacctgatgcgccgctcgctgcagcacgccgagggcgccggtctcgcgctg
cccaagctgctggagaccgattacgtcaacaccatcccgaccgccgccgagcccgcgttc
gacggcgacctggagatggagtcgaggatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacccggggcgcccggtacggggtcggcggccacatcgccaccttcgcctcggcg
gcctggctctacgagaccggcttcaaccacttcttccgcggcaaggagggggacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggctcaacgagcagcagctcgacaacttccgccaggagtccggtggcgagggc
ctgccctcctacccgcacccccggcggctgccctggctgtgggagttccccaccgtgtcg
atgggcctcggcccgctctcggccatctaccaggcgcgcttcaaccgctatctggccaac
cgcaacatcaaggacacggccaactcgcacgtctgggccttcctgggcgacggcgagatg
gacgagcccgagtcgaccgccgccctcgcgctggcctcccgtgagcagctcgacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttccgc
gtggtccaggagctggaggcgcagttccgcggggccggctggaacgtcgtcaagacgctc
tggggcaacgcctgggacgagctgttccagctggacacccagggtgcgctgctgcgccgc
ctgcgtgaggtcccggacgcgcagttccagacgtacgccacccgcgacgtcgcctacatc
cgcgagcacttcttcggcaccgagcccgcgctcgtcgagctggcgaagctgctcaccgac
gcgaagatcggcgagtgtttctacacctcgcgcggcggccacgaggcccgcaaggtctac
gcggcgtaccgggcggccgtcgagcacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggctacacgctcggcaagggcttcgagtccaagaacgccaaccaccagatgaag
aagctgtcgatcgacgagttcaagggcatgcgcgagctgctcggcctcccgatccccgac
agcgccttcgaggacggtctcgtcccctacggccaccccggcgccgactcccccgaggtc
cgctacctccaggagcgccgtgccgccctcggcggccccgcccccgcccgccgggtgcac
gcggtggcgcttccgcagcccgaggagcgcgcgttcaaggccctgtacaaggggtccggc
aagcaggagatggccaccaccatggcgttcgtccgcctggtgaaggacctgatgcgggac
aaggagaccggcaagcgctgggtgccgatcgtcccggacgaggcccgtaccttcggtatg
gagtccctcttcccgtccgccggcatctactcgccgctgggccagacgtacgatccggtc
gaccgcgaccagctgatgtactacaaggaagccaaggacggccagatcctcaacgagggg
atcaccgaggccggctcgatggcggacttcatcgccgcgtccacgtcctacgcgacgcac
ggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcggaccggc
gaccagatgtggcagctcgccgaccagctcggcaagggcttcatcgtcggcgccaccgcc
ggccgtacgaccctgacgggtgagggcctccagcacgcggacggccactcgcacctgatc
gcggccaccaacccggcctcgctcaactacgacccggcgttcgcgtacgaggtcgcggtg
atcgtcaaggacggtctgcgccggatgtacggccccgaggccgagaacgtcttctactac
ctgacggtctacaacgagccgaagccccagcccgcgatgcccgagggcgtcgaggagggc
atcgtcaagggcctgtaccgcttcaaggagggcacgcccgcgaaggcggacgcgccgcgc
ctccagctgctcgcctccggtacggcgatccactgggccctggaggcccaggagctgctg
gccgccgactggggtgtcacggccgacgtctggtccgccacctcgtggggcgagctgcgc
cgcgacgcgctggaggccgacgaggcgctgctccgcggtgagcagcaggtcccgtacgtg
acgcaggcgctctccggtgcgccgggcccggtgctcgcggtcagcgactggatgcgccag
gtcccggaccagatcagccagtgggtggagcaggactggtcctcgctcggcacggacggc
ttcggtctctccgacacccgcgccgcggcccgccgccacttcggcgtcgacgcccagtcg
atcgtggtggcctcgctggcccagctcgccaggcgcggcgaggtcccggcctccgcgatc
aaggaggcccgggagcgctacgggctctga
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