KEGG T00182: SAR2147

Staphylococcus aureus subsp. aureus MRSA252 (MRSA): SAR2147

Entry

SAR2147           CDS       T00182

Symbol

leuD

Name

(GenBank) 3-isopropylmalate dehydratase small subunit

K01704

3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]

Organism

sar Staphylococcus aureus subsp. aureus MRSA252 (MRSA)

Pathway

sar00290

Valine, leucine and isoleucine biosynthesis

sar00660

C5-Branched dibasic acid metabolism

sar01100

Metabolic pathways

sar01110

Biosynthesis of secondary metabolites

sar01210

2-Oxocarboxylic acid metabolism

sar01230

Biosynthesis of amino acids

Module

sar_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Brite

KEGG Orthology (KO) [BR:sar00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    SAR2147 (leuD)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SAR2147 (leuD)
Enzymes [BR:sar01000]
4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     SAR2147 (leuD)
    4.2.1.35  (R)-2-methylmalate dehydratase
     SAR2147 (leuD)

SSDB

Motif

Pfam:

Aconitase_C

Other DBs

NCBI-ProteinID:

CAG41128

UniProt:

Q6GF13

LinkDB

Position

2211099..2211671

AA seq 190 aa
MAAIKPITTYKGKIVPLFNDNIDTDQIIPKVHLKRISKSGFGPFAFDEWRYLPDGSDNPD
FNPNKPQYKGASILITGDNFGCGSSREHAAWALKDYGFHIIIAGSFSDIFYMNCTKNAML
PIVLEKNAREHLAKYVEIEVDLPNQTVSSPDKSFHFEIDETWKNKLVNGLDDIAITLQYE
SLIEKYEKSL

NT seq 573 nt +upstreamnt +downstreamnt
atggcagcaatcaaacctattacaacatataaaggtaaaatagtccctcttttcaacgac
aatatcgatacagaccaaatcattcctaaagtacacttaaagcgtatttcaaaaagtggc
tttggtccatttgcttttgatgaatggcggtacttacctgatggttcagataatcctgat
ttcaatccaaataagcctcaatataaaggtgcatccatattaattactggagataatttt
ggatgtggttcaagtcgtgaacatgcagcttgggcacttaaggactatggctttcatatt
ataattgcaggaagtttcagtgacattttttatatgaattgtacaaaaaatgcaatgtta
ccaattgttttagaaaaaaatgcacgtgaacatcttgctaaatatgttgaaattgaggtc
gatttaccaaatcaaactgtgtcatcaccagacaagagtttccattttgaaattgatgaa
acttggaagaataaacttgtaaatggcttagatgacattgcaatcaccctacaatatgaa
tcattaatagaaaaatatgaaaaatcactttaa

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