Sorex araneus (European shrew): 101538217 Help Entry 101538217         CDS       T07854                                  Symbol SPHK2 Name (RefSeq) sphingosine kinase 2 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism sara  Sorex araneus (European shrew) Pathway sara00600   Sphingolipid metabolism sara01100   Metabolic pathways sara04020   Calcium signaling pathway sara04071   Sphingolipid signaling pathway sara04072   Phospholipase D signaling pathway sara04148   Efferocytosis sara04370   VEGF signaling pathway sara04371   Apelin signaling pathway sara04666   Fc gamma R-mediated phagocytosis sara05152   Tuberculosis Module sara_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     101538217 (SPHK2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     101538217 (SPHK2)    04371 Apelin signaling pathway     101538217 (SPHK2)    04020 Calcium signaling pathway     101538217 (SPHK2)    04072 Phospholipase D signaling pathway     101538217 (SPHK2)    04071 Sphingolipid signaling pathway     101538217 (SPHK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     101538217 (SPHK2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     101538217 (SPHK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     101538217 (SPHK2) Enzymes [BR:sara01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      101538217 (SPHK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  101538217 NCBI-ProteinID:  XP_004619862 LinkDB All DBs Position Unknown AA seq 654 aa AA seqDB search MNGPLRATEKQDQKPDRELTWSWGHGPRSALRPAEAMAPPPLPPLAASTPLLHGEFGSYP ARGSRFALTLTPQALHIQRLRPKPEARPRGGLVSLAEVSGCSTLRSRSPSDSAAYFCVYT YPRGRRGGRRRDARTFQVDGGATYEENRAEAQRWAATLTCLLRGLPLPGDGEINLELLPR APRLLLLVNPYGGRGLAWQWCKNHVLPMIAEAGLSFNLIQTERQNHARELVQGLSLSEWD GIITVSGDGLLYEVLNGLLDRPDWEEAVKTPVGVLPCGSGNALAGAVNQHGGFQQALGLD LLINCSLLLCRGGDCPLDLLSVTLASGARCFSFLSVAWGFVSDVDIQSERFRALGSARFT LGTVLGLAALHTYRGRLSYLPATVEPASSPTGHGLPRAKSELTLVPAPAPPMAHSPLHRS VSDLPLPLPQPQTALTSPGSPEAMPSLALNGGAPELAGDWGGAGDAPLSPDPLLHSPPGT PKVTPLSPITEGVPEVPLPIGQPAPTPDSPVASSAGGPPDHLLPPLGSPLPPGWVTLEGD FVLMLAISPSHLGADLVAAPHARFDDGLVHLFWVRSGISRAALLRLFLAMERGNHFRLGC PQLGYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQVHPGLGTLLTGPPGREP NT seq 1965 nt NT seq  +upstreamnt  +downstreamnt atgaatggacccctcagagcaacagagaagcaggaccagaagccggaccgggagctgact tggagctggggccacgggcctcggagcgccctgcgcccagcagaggccatggccccgcca ccactgccaccgctggctgccagcaccccgctcctgcatggcgagtttggctcctacccg gcccggggctcacgcttcgccctcactctcacaccacaggccctgcacatacagcggctg cgccccaagcccgaagcccggccccggggaggcctggtctcgctggctgaggtctccggc tgcagcaccctgcggagccgcagcccctcggactcggccgcctacttctgtgtctacacc tacccccggggccggcgtgggggccgccgcagagatgcccgcaccttccaggtggacggg ggcgccacctatgaggagaaccgggccgaggcccagcgctgggctgccacgctgacctgc ctgctgcggggactgccactgccaggggatggggaaatcaacctggagcttctgccgcgt gcaccccggctgctcctattggtcaatccctacggggggcggggcctggcctggcagtgg tgcaagaaccacgtgctgcccatgatcgctgaggcgggcctgtccttcaaccttatccag acagaacgacagaaccacgcccgggagctggtccagggtttgagcctgagcgagtgggat gggatcatcacagtctctggggacgggctgctgtacgaggtactcaatggtcttctggat cggcctgactgggaggaggctgtgaagacgcctgtgggtgtccttccctgcggctctgga aacgcgctggcaggagctgtgaaccaacatggggggttccagcaggccctgggcctcgac ctgctcatcaactgctcgctgctgctctgccggggcggggactgcccactggacctactc tccgtcaccctggcctcgggcgcccgctgtttctccttcttgtctgtggcctggggcttt gtgtcagatgtggacatccagagtgagcgcttccgggccctgggaagcgcccgcttcaca ctgggcacggttctgggcctggccgcactgcacacttaccgaggacgcctctcctacctc cctgccaccgtggagccagcgtcgtctcccaccggccatggcctgccccgtgccaaatct gagctgaccttggtcccggccccagcgccacccatggcccattcacccctacaccgttca gtgtctgatctccccctcccccttccccagccccagacggccctcacctccccaggctcc ccagaagccatgcccagtctggccctcaatggtggggccccagagctggctggggactgg ggtggagccggggatgcgcctctgtccccggaccccctgctgcactcaccccctggcacc ccgaaggtgactccgctctcgcccatcacagagggtgtcccagaagtgcccctgcctatt gggcagcccgcgcccacccctgactccccagtggccagttcagctgggggcccaccagac cacctgctccctcctctgggcagcccactgcccccgggctgggtgacgctggagggagac tttgtgctcatgctggccatctcgcccagccacctgggagccgacctggtggccgcaccc catgcgcgcttcgacgatggcctggtgcaccttttctgggtgcgaagcggcatctcccgc gcagcactgctgcgcctgttcctggccatggagcggggcaaccacttccgcctgggctgc ccacaactgggctatgcagcggcccgcgccttccgcctggagccgctcacgccccgaggt gtgctcacggtggacggcgagcaggtggagtacggacccctgcaggcccaggtgcacccg ggcctaggcacccttctcactgggccgccagggcgggagccttga

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