Sorex araneus (European shrew): 101540363 Help Entry 101540363         CDS       T07854                                  Symbol IL6 Name (RefSeq) interleukin-6   KO K05405   interleukin 6 Organism sara  Sorex araneus (European shrew) Pathway sara01521   EGFR tyrosine kinase inhibitor resistance sara01523   Antifolate resistance sara04060   Cytokine-cytokine receptor interaction sara04061   Viral protein interaction with cytokine and cytokine receptor sara04066   HIF-1 signaling pathway sara04068   FoxO signaling pathway sara04151   PI3K-Akt signaling pathway sara04218   Cellular senescence sara04620   Toll-like receptor signaling pathway sara04621   NOD-like receptor signaling pathway sara04623   Cytosolic DNA-sensing pathway sara04625   C-type lectin receptor signaling pathway sara04630   JAK-STAT signaling pathway sara04640   Hematopoietic cell lineage sara04657   IL-17 signaling pathway sara04659   Th17 cell differentiation sara04668   TNF signaling pathway sara04672   Intestinal immune network for IgA production sara04931   Insulin resistance sara04932   Non-alcoholic fatty liver disease sara04933   AGE-RAGE signaling pathway in diabetic complications sara04936   Alcoholic liver disease sara05010   Alzheimer disease sara05020   Prion disease sara05022   Pathways of neurodegeneration - multiple diseases sara05132   Salmonella infection sara05133   Pertussis sara05134   Legionellosis sara05135   Yersinia infection sara05142   Chagas disease sara05143   African trypanosomiasis sara05144   Malaria sara05146   Amoebiasis sara05152   Tuberculosis sara05161   Hepatitis B sara05162   Measles sara05163   Human cytomegalovirus infection sara05164   Influenza A sara05166   Human T-cell leukemia virus 1 infection sara05167   Kaposi sarcoma-associated herpesvirus infection sara05168   Herpes simplex virus 1 infection sara05169   Epstein-Barr virus infection sara05171   Coronavirus disease - COVID-19 sara05200   Pathways in cancer sara05202   Transcriptional misregulation in cancer sara05321   Inflammatory bowel disease sara05323   Rheumatoid arthritis sara05332   Graft-versus-host disease sara05410   Hypertrophic cardiomyopathy sara05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:sara00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101540363 (IL6)    04668 TNF signaling pathway     101540363 (IL6)    04066 HIF-1 signaling pathway     101540363 (IL6)    04068 FoxO signaling pathway     101540363 (IL6)    04151 PI3K-Akt signaling pathway     101540363 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101540363 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     101540363 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     101540363 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101540363 (IL6)    04620 Toll-like receptor signaling pathway     101540363 (IL6)    04621 NOD-like receptor signaling pathway     101540363 (IL6)    04623 Cytosolic DNA-sensing pathway     101540363 (IL6)    04625 C-type lectin receptor signaling pathway     101540363 (IL6)    04659 Th17 cell differentiation     101540363 (IL6)    04657 IL-17 signaling pathway     101540363 (IL6)    04672 Intestinal immune network for IgA production     101540363 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101540363 (IL6)    05202 Transcriptional misregulation in cancer     101540363 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101540363 (IL6)    05161 Hepatitis B     101540363 (IL6)    05171 Coronavirus disease - COVID-19     101540363 (IL6)    05164 Influenza A     101540363 (IL6)    05162 Measles     101540363 (IL6)    05168 Herpes simplex virus 1 infection     101540363 (IL6)    05163 Human cytomegalovirus infection     101540363 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     101540363 (IL6)    05169 Epstein-Barr virus infection     101540363 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     101540363 (IL6)    05135 Yersinia infection     101540363 (IL6)    05133 Pertussis     101540363 (IL6)    05134 Legionellosis     101540363 (IL6)    05152 Tuberculosis     101540363 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     101540363 (IL6)    05144 Malaria     101540363 (IL6)    05142 Chagas disease     101540363 (IL6)    05143 African trypanosomiasis     101540363 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     101540363 (IL6)    05321 Inflammatory bowel disease     101540363 (IL6)    05332 Graft-versus-host disease     101540363 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     101540363 (IL6)    05020 Prion disease     101540363 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     101540363 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101540363 (IL6)    05410 Hypertrophic cardiomyopathy     101540363 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101540363 (IL6)    04932 Non-alcoholic fatty liver disease     101540363 (IL6)    04931 Insulin resistance     101540363 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     101540363 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101540363 (IL6)    01523 Antifolate resistance     101540363 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:sara04052]     101540363 (IL6) Cytokines and neuropeptides [BR:sara04052]  Cytokines   Interleukins    101540363 (IL6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 IL11 GCSF Motif Other DBs NCBI-GeneID:  101540363 NCBI-ProteinID:  XP_004604146 LinkDB All DBs Position Unknown AA seq 214 aa AA seqDB search MSSLSPRAFSPVAFSLGLLLVLATAFPTPAPLGEEATDAAAPTLPPVTSPERTEDLIKYI LGKISLLKKELCGKYGKCENVKEALAENSLNLPKMANGVECFPSRFDQEPCLIRITSGLL EFQIYLEYLQKVFDGDKKNAMDVHDNTKNLVQLLKQNVKNPDEVTTPDPSHSANVLSWLQ SQSQKNWLQSTTFHMMLQSLEDFLQFSLRAVRIM NT seq 645 nt NT seq  +upstreamnt  +downstreamnt atgagctcgctgtccccacgcgccttcagtccagtcgccttctccctggggctgctcctg gtgctggctactgccttccccaccccggcccccctgggagaagaggccacggatgctgcc gccccgaccctgccgcccgtcacctctcccgaaagaaccgaagacctcattaagtacatc ctgggcaaaatctcgctactgaaaaaggagctgtgtggcaagtacggcaagtgtgagaac gtgaaggaagcactggcagagaacagcctgaaccttccgaagatggcaaatggagtggaa tgcttcccgtccaggtttgatcaggagccttgcctgataagaatcacctccggtctcttg gagtttcagatatacctagagtaccttcagaaagtgtttgatggtgataagaaaaatgcc atggatgtgcatgacaataccaaaaacctggttcagctcctgaagcaaaacgtgaagaac ccggatgaagtcacgactccagaccccagccacagtgccaacgtgctcagctggctacag tcccagtcccagaaaaactggctacagagcaccacgttccacatgatgctgcagagcctg gaggacttcctgcagttcagcctgagggccgtccgaatcatgtag

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