Sorex araneus (European shrew): 101546832 Help Entry 101546832         CDS       T07854                                  Symbol ACACB Name (RefSeq) acetyl-CoA carboxylase 2   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism sara  Sorex araneus (European shrew) Pathway sara00061   Fatty acid biosynthesis sara00620   Pyruvate metabolism sara00640   Propanoate metabolism sara01100   Metabolic pathways sara04152   AMPK signaling pathway sara04910   Insulin signaling pathway sara04920   Adipocytokine signaling pathway sara04922   Glucagon signaling pathway sara04931   Insulin resistance sara04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     101546832 (ACACB)    00640 Propanoate metabolism     101546832 (ACACB)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     101546832 (ACACB)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     101546832 (ACACB)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     101546832 (ACACB)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101546832 (ACACB)    04922 Glucagon signaling pathway     101546832 (ACACB)    04920 Adipocytokine signaling pathway     101546832 (ACACB)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101546832 (ACACB)    04931 Insulin resistance     101546832 (ACACB) Enzymes [BR:sara01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      101546832 (ACACB)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      101546832 (ACACB)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      101546832 (ACACB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 Motif Other DBs NCBI-GeneID:  101546832 NCBI-ProteinID:  XP_004615655 LinkDB All DBs Position Unknown AA seq 2337 aa AA seqDB search MILLLLLSCLISYCLTFSWLKIWRKMADSTGSTDNPPEVDFPPSPEPSAASGAPQLHVED RSSPPKTPQTAEPASLKGARDARRQKPSRHPTHLKPPRTPVGPDSASEAGPADPLAPDTN GLVTVEGPAQGPRARTLSREDEKQAHIKRQLMTNFILGSFDDNSSDEDAAAFQHSSRKGS RASLGAPSLEAALAAGRLEVPTSEIRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVT RFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIK MADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLRKHDIAFL GPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVAWSEEDLKQGKRIRVPEDVYDQG CVKDIDEGLEAAEKIGFPLMIKASEGGGGKGIRKAKSAEDFPILFRQVQSEIPGSPVFLM KLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAV RLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVP LHRLKDIRLLYGESPWAVTPISFETPANPPMARGHVIAARITSENPDEGFKPSSGTVQEL NFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRT TVEYLINLLETENFQSNAIDTGWLDHLIAQKVQAEKPDIMLGVVCGALNVADAMFRTCMT DFLHSLERGQVLPADSLLNIVDVELIYGGIKYILKVTRQSLTMFVLIMNGGHIEIDAHRL NDGGLLLSYNGSSHTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLIQYLVED GGHAEAGSSYAEMEVMKMIMTLSVQESGRVRYLKRPGAVLEAGCVVAHLELDDPSKVHAA EPYTGELPAQPTLPILGEKLHQVFHNVLENLTNVMNGYCLPEPIFSVKLKEWVQKLMMTL RHPTLPLLELQEIMTSVSGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQQIASILDCHA ATLQRKADREAFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRKYLQVENHFQQAHYDKC VINLREQLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELTSILSELTQL SKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAVDMYGHEFCPDNLKKLILSETT IFDVLPTFFYHTNQVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTFLVEFQFMLPSSHP NRMAVPISATNPNLLRHSTELYMDSGFSPPCQRLGAMVAFRRFEDFTRNFDEVISCFANV PRDTPLFSTAHSTLYSELDSKGPREEPIHILNVAIQSADHLEDEELVPIFRTFVQSKKNI LVEYGLRRITFLIAQEKEFPKFFTFRARDQFAEDRIYRHLEPALAFQLELSRMRNFELRA VPCANHKMHLYLGAARVKEGAEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEA MDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPYKIEEAVRSMVMRYGSRLWKLRVLQAEV KINIRESTSGKAVPIRLFLTNESGYYLDISLYEEVTDQRSGNIMFQSFGNKQGPQHGMLI NTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPDKYPKDILTYTELVLDP QGQLVEMNRVPGGNEVGMVAFRMKLKTPEYPEGRDVIVIGNDITFRIGSFGPGEDLLYMR ASELARAEGIPKIYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGYKYLYLTPQDYTRI SPLNSVHCTHVEEDGESRYVITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIVTISLVT CRALGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHNNGVA HITVPDDFEGVYTILEWLSYVPKDNHSPVPIITPTDPIDREIEFQPSRAPYDPRWMLAGR PHPTMKGSWQSGFFDQGSFREILQPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADP ANLDSEAKGAPLGAEPSWYMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVV DPTINPLCTEMYADKESRGGVLEPEGTVEIKFRQKDLTKAMRRIDPVYKKLAEQLASKKL SEKETREVEAQLKDREEQLLPIYHQVAVQFADLHDTPGRMLEKGVISTWDRRDLTGSASS PVPSGLWNAHQRQAHVLVEENPEVAVDCMMHLSQHISAAERAQLAQLLSTMDSPAST NT seq 7014 nt NT seq  +upstreamnt  +downstreamnt atgatcctcctgcttctcctgtcttgcctgatttcctactgtctgaccttttcctggtta aaaatctggagaaaaatggccgactccacagggagcactgataacccaccggaagtggac ttccccccgagcccggagccctcggcagcctcaggagccccccagctgcacgtggaggac cgcagctctccgccaaagaccccccagacggcagagccagcgtccctcaaaggcgccagg gatgctcggcgccaaaaaccctcccggcatcccactcacctcaagcccccaaggaccccc gttggccccgacagcgcctcggaggcagggccagcagaccccctggccccggacaccaac ggccttgtgacggtggagggccccgcccagggcccgcgggcccggacgctgtccagggag gacgagaagcaggcgcacatcaagaggcagctgatgaccaacttcatcctgggctccttc gacgacaactcctccgacgaggacgctgccgccttccagcactcgtcccgcaagggcagc cgggccagcctgggggccccgtccctggaagccgctctggccgcgggccgtcttgaggtc cccacgtctgagatcaggcccagcatgtccggactccatctggtgaagaggggccgagag cacaagaagctggatctgcacagagacttcactgtggcctccccagccgagtttgtcaca cgcttcgggggggaccgggtcattgagaaggtgctcatcgccaacaatggcatcgcggcc gtgaagtgcatgcgctccatccgcaggtgggcctacgagatgttccggaacgagcgggcc atccgcttcgtcgtcatggtgacgccagaggacctcaaggccaatgcagagtacatcaag atggcagaccagtacgtgcccgtcccgggaggccccaacaacaacaactacgccaacgtg gaactgattgtggacattgccaaaaggatccccgtgcaggccgtgtgggctggctggggc cacgcctcggagaaccccaagctcccggagctccttcgcaaacacgacatcgctttctta ggcccccccagcgaggccatgtgggccctgggggataagatcgcgtccaccatcgtggcc cagacgctgcagatcccaaccctgccctggagtggaagcggcctgaccgtggcatggtca gaggaagacctgaagcaggggaagagaatccgcgtccccgaagatgtttacgaccagggc tgtgtgaaagacattgatgagggtctggaggcggcagagaagatcggttttccgttgatg atcaaagcttctgaaggcggaggagggaaagggatccggaaggccaagagcgccgaggac ttccccatcctcttcagacaagtgcagagcgagatcccaggctcccccgtcttcctcatg aagctggcccagcacgcgcggcacctggaggtgcagattctggccgaccagtacggcaac gccgtgtccctgttcgggcgcgactgctccatccagcggcgccaccagaagatcatcgag gaggcaccggccaccatcgccaccccagctgtgttcgagtttatggagcagtgcgccgtg cgcctggccaagacggtgggctacgtgagcgcgggcacggtggagtacctctacagccag gacggcagcttccacttcctggagctgaacccccgcctgcaggtggagcacccctgcacg gagatgatcgccgacgtcaacctgccggccgcccagttacagatcgccatgggcgtcccg ctgcaccggctgaaggacatccgcctcctgtacggggagtccccctgggccgtgacgccc atctccttcgagactcctgccaacccgcctatggcccgcggccacgtcatcgccgccagg atcaccagtgagaaccccgatgaggggttcaagcccagctccgggacggtccaggaactg aatttccgcagcaacaagaatgtgtggggttacttcagtgtggcggctgccggcggcttg cacgagtttgcggattctcagttcgggcactgcttctcctggggggagaaccgggaagag gccatctcgaacatggtggtggcgctgaaggagctgtccatccgcggggacttcaggacc accgtggagtatctcatcaacctcctggagacggagaacttccagagcaacgccatcgac accggctggctggatcacctcatcgcccagaaagtgcaggccgagaagccggacatcatg ctgggcgtggtgtgcggggccttgaacgtggccgacgcaatgttcagaacctgcatgaca gacttcctgcactcgctggaaaggggccaggtcctgcccgcagactcgctgctcaacatc gtggacgtggagctcatctacggcggcatcaagtacattctcaaggtgacccggcagtcg ctcaccatgttcgtgctcatcatgaacggcggccacatcgagattgacgcccaccggctc aacgacgggggtctgctgctgtcctacaacgggagcagccacaccacctacatgaaggag gaggtggacagttaccgcatcaccatcggcaacaagacgtgcgtgtttgagaaggagaac gaccccacagtgctgaggtcgccctcggccgggaagctgatccagtacctggtggaggat gggggccacgcggaggccggcagcagctacgccgagatggaggtgatgaagatgatcatg accctgagcgtgcaggagagtggccgcgtgcgctacctcaagcgccccggggccgtgctg gaggcgggctgtgtggtggcccacctggaacttgacgacccttccaaggtgcatgcggcc gagccctacacgggggagctccccgcccagcccacgctgcccatcctgggcgagaagctg caccaggttttccacaacgtgctggagaacctgaccaacgtcatgaacggctactgcctg ccggagcccattttcagcgtcaaactgaaagagtgggtgcagaagctcatgatgaccctc cggcaccccacgctgccgctgctggagctgcaggagatcatgacgagcgtgtcgggccgc atccccgcgcccgtggagaaggcggtccgccgggtcatggcgcagtacgccagcaacatc acctcggtgctgtgccagttccccagccagcagatagccagcatcctggactgccacgcg gccaccctgcagcgcaaggccgaccgggaggccttcttcatgaacacgcagagcatcgtg cagctggtgcagaggtaccgcagcggcacccgaggctacatgaaggcggtggtgctggac ctcctgcgaaagtacctccaagtcgagaaccatttccagcaagcccactacgacaagtgt gtcatcaacctcagggagcagctgaagccagacatgtcccaggtgctggactgcatcttc tcccacgcgcaggtggccaagaagaaccagctggtgatcatgctgatcgatgagctctgt ggccccgacccctctctgtccgacgagctgacctccatcctcagcgaactcacacagctg agcaaaagcgagcactgcaaggtggccctgagggccaggcaggtcctgatcgcctcccac ctcccctcctacgagctccggcacaaccaggtcgagtccatcttcctgtcggccgtggac atgtacggccacgagttctgcccggacaacctcaagaaattaatcctttcagaaacaacc atctttgacgtcctgcccaccttcttctaccacacgaaccaggttgtctgcatggcgtcc ctggaggtgtacgtgcggaggggctacatcgcctacgagctcaacagcctgcagcaccgg cagctccctgacggcaccttcctggtggagttccagttcatgctgccctcctcccacccg aaccggatggccgtgcccatcagcgccaccaaccccaacctgctgcggcacagcacggag ctctacatggacagcggcttctccccgccctgccagcgcctgggtgccatggtcgccttc cggagattcgaggacttcaccaggaactttgacgaggtcatctcctgctttgccaacgtg cccagggacaccccgctcttcagcacggcccacagcaccctctactctgagctagacagt aagggcccccgggaggagcccatccacatcctgaacgtggccatccagagcgccgaccac ctggaggacgaggagctggtgcccatcttcaggaccttcgtacagtccaagaaaaatatc ctggtggaatatggactccggagaatcaccttcctgattgcccaagagaaagaatttccc aagtttttcaccttccgggccagagaccagttcgcggaagaccgcatctaccggcacctg gagcccgcgctggccttccagctggagctcagccgcatgcgcaacttcgagctccgcgcc gtgccctgcgccaaccacaagatgcacctgtacctgggcgccgcccgcgtgaaggagggc gcggaggtcaccgaccataggttcttcatccgggccatcatcaggcactcggacctgatc accaaggaagcgtccttcgagtacctgcagaacgagggggagcggctgctgctggaggcc atggacgagctggaggtggccttcaacaacacgagcgtgcgcaccgactgcaaccacatc ttcctcaacttcgtgcccaccgtcatcatggacccctacaagatcgaggaggccgtccgc tccatggtcatgcgctacggcagccggctctggaagctgcgcgtgctgcaggccgaggtc aagatcaacatccgcgagtccacctcgggcaaggccgtccccatccgcctgttcctcacc aacgagtccggctactacctggacatcagcctctacgaggaggtgaccgaccagagatct ggaaacatcatgttccagtccttcggcaacaagcaagggccccagcacgggatgctgatc aacacgccctacgtcaccaaggacctgctccaggccaagcggttccaggcccagtccctg gggaccacctacgtgtacgacttcccggaaatgttcaggcaggctctcttcaaactgtgg ggctccccggacaagtaccccaaggacatcctgacctacacagagctagtgctggaccct cagggccagctggtagagatgaaccgagtgccgggaggaaacgaggtgggcatggtggcc ttcaggatgaagctgaagacgccggagtaccccgaggggcgtgatgtcatcgtcatcggc aacgacatcaccttccgcatcggttccttcggccccggcgaagacctcctgtacatgcgg gcctcggagttggcccgggccgagggcatccccaagatctaccttgccgccaacagcggg gcccgcatcggcctcgcggaggagatcaagcacatgttccaggtggcctgggtcgaccca gaagacccccacaagggctacaagtacctgtacctgaccccgcaagactacacccgcatc agcccgctgaactcggtgcactgcacgcacgtcgaggaggacggcgagtccaggtacgtc atcacggatattatcggcaaggacgacgggctgggcgtggagaacctcaggggctcgggc atgatcgccggggagtcctcgctggcttacgaggagatcgtcaccatcagcttggtgacc tgccgagccctgggcatcggggcgtacctggtgaggctgggccagcgggtgatccaggtg gagaactcccacatcatcctgacgggagcaggcgctcttaacaaggttctgggccgagaa gtgtacacgtccaacaaccagctgggtggcgtgcagatcatgcacaacaacggcgttgcc cacatcaccgtgcccgacgacttcgagggtgtctacaccatcctggagtggctgtcctac gtgccaaaggacaaccacagccctgtccccatcatcacacccactgatcccatcgaccgg gaaattgagtttcagccgtccagggctccctacgacccccggtggatgctggcaggacgg cctcacccaaccatgaagggctcctggcagagcggcttcttcgaccagggcagcttccgg gaaatcctgcagccctgggcccagaccgtggtgacgggacgagccaggctggggggcatc ccggtgggggtgatcgccgtggagacgcggaccgtggaggtggccgtgcccgcagacccc gccaacctggattccgaggccaagggggctcctctgggggctgagccttcctggtacatg tacgaccaggtgctgaagttcggcgcctacatcgtggacggcctgcggcagtacaagcag cccatcctcatctacatcccgccctacgccgagctccgggggggctcctgggtggtcgtg gaccccaccatcaaccccctgtgcaccgagatgtacgcagacaaagagagcagggggggt gttctggagccagaaggaaccgtggagattaagttccggcagaaagatctcacgaaggcc atgagaaggatcgacccagtttacaagaaacttgcggaacagctggcctccaagaagctc tcagagaaggaaacgcgggaggtggaggcgcagttgaaggaccgggaggagcagttgctg cccatctaccaccaggtggcagtgcagttcgccgacctgcacgacaccccgggccgcatg ctggagaagggcgtgatctcgacgtgggacaggagggacttgacgggctccgcctccagc cctgtgcccagtggcctctggaacgcccaccagcgccaggcccacgtcctggtggaggag aacccggaagtggccgtggactgcatgatgcacctaagccagcacatcagtgcggccgag cgcgcccagctggcccagctcctgtctaccatggacagcccggcctccacctga

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