Sorex araneus (European shrew): 101549202
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Entry
101549202 CDS
T07854
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara04120
Ubiquitin mediated proteolysis
sara04144
Endocytosis
sara04330
Notch signaling pathway
sara04668
TNF signaling pathway
sara04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101549202 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101549202 (ITCH)
04668 TNF signaling pathway
101549202 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101549202 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101549202 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
sara04131
]
101549202 (ITCH)
04121 Ubiquitin system [BR:
sara04121
]
101549202 (ITCH)
Enzymes [BR:
sara01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
101549202 (ITCH)
Membrane trafficking [BR:
sara04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
101549202 (ITCH)
Ubiquitin system [BR:
sara04121
]
Ubiquitin ligases (E3)
HECT type E3
101549202 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
101549202
NCBI-ProteinID:
XP_004612612
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYDTLKSNNMKFEDVVITL
QLTGDKEPTETIGDLSICLDGMQLESEVVTNGETTGSESASQNDDGSRSKDETRVNTSGS
DDPEDAGSGENRRVSGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTTSSTSEGAASGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDNNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHTKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgttatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagttgatggacagtcaaagaagacagaaaagtgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcactcctgtgagtaaattacat
tttcgtgtgtggagccaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgacacattaaaatcaaacaatatgaaatttgaggacgttgttataacttta
cagcttacaggtgacaaagaaccaacagaaacaataggagacttatcaatttgtcttgat
ggaatgcaactagaatctgaagttgttaccaatggtgaaactactggttcagaaagtgct
tcccagaatgatgatggttccagatccaaggatgaaaccagagtgaatacaagtggatca
gatgaccctgaagatgcaggatctggtgaaaataggagggtcagtgggaataattctcca
tcactctcaaatggcggttttaagccctctaggcctccaagaccttcacgaccacctcct
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatctagtactggatctctgccaccaacaaacacaacttccagtacatctgaaggagca
gcttctggattaataattcctcttactatatctggaggttcaggccctaggccactaaat
cctgttcctcaagctcccctcccacctggttgggaacaaagagtggaccagcatggacga
gtttactatgttgatcatattgaaaagagaaccacgtgggatagaccagaacctctacct
cctgggtgggaacgacgggttgataatatgggtcgtatttattatgttgatcatttcaca
agaacaacaacttggcagaggccaacattagaatctgtccggaactatgaacagtggcag
ctccaacgtagtcaacttcagggagcaatgcagcagtttaaccagaggttcatttatggg
aatcaagatttgtttgccacatcacaaaataaagaatttgatcctcttggtcccttgcca
ccgggatgggagaagagaacggacaacaatggtagagtatattttgtcaaccacaatact
cgtataacccaatgggaagaccccagaagtcaaggccaattaaatgaaaaacccttacct
gaaggctgggaaatgagattcacagtggatggaattccttattttgtggatcataataga
agaactaccacctatatagatccccgcacaggaaaatctgccctagacaatggaccccag
atagcctatgtacgagacttcaaggcaaaggttcagtatttccgtttctggtgtcagcaa
ctggccatgccacagcacacaaagattacagtgacaagaaaaacattgtttgaggattcc
tttcaacagataatgagcttcagtcctcaagatctgcgaagacgtttgtgggtgattttt
ccgggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtct
catgaagtgttgaacccaatgtattgcctgtttgaatatgcaggaaaggataactactgc
ttgcaaataaaccctgcttcttatatcaatccagatcatctgaaatattttcgttttatt
ggcagatttattgccatggctctgttccatgggaagtttatagacactggtttttcttta
ccattctataagcgtatcttgaacaaaccagttgggctcaaggatttagaatccattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaagaatgtggtttg
gaaatgtacttctccgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaagaactagaggtcctt
ttatgtggaatgcaagagattgatttgaatgattggcaaagacatgctatctaccgtcat
tatactagaacaagcaaacaaatcatgtggttctggcagtttgttaaagaaattgataat
gagaaaagaatgagacttctgcagtttgttactggaacctgccgactaccagttggagga
tttgctgacctcatggggagtaatggaccacagaaattttgcattgaaaaagttggaaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccatataag
agctatgagcaactgaaggaaaagttgttatttgccattgaagaaacagaaggatttgga
caagaataa
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