Sorex araneus (European shrew): 101551819 Help Entry 101551819         CDS       T07854                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism sara  Sorex araneus (European shrew) Pathway sara00230   Purine metabolism sara01100   Metabolic pathways sara01522   Endocrine resistance sara04015   Rap1 signaling pathway sara04022   cGMP-PKG signaling pathway sara04024   cAMP signaling pathway sara04062   Chemokine signaling pathway sara04072   Phospholipase D signaling pathway sara04081   Hormone signaling sara04082   Neuroactive ligand signaling sara04114   Oocyte meiosis sara04211   Longevity regulating pathway sara04213   Longevity regulating pathway - multiple species sara04261   Adrenergic signaling in cardiomyocytes sara04270   Vascular smooth muscle contraction sara04371   Apelin signaling pathway sara04540   Gap junction sara04611   Platelet activation sara04713   Circadian entrainment sara04714   Thermogenesis sara04723   Retrograde endocannabinoid signaling sara04724   Glutamatergic synapse sara04725   Cholinergic synapse sara04726   Serotonergic synapse sara04727   GABAergic synapse sara04728   Dopaminergic synapse sara04750   Inflammatory mediator regulation of TRP channels sara04911   Insulin secretion sara04912   GnRH signaling pathway sara04913   Ovarian steroidogenesis sara04914   Progesterone-mediated oocyte maturation sara04915   Estrogen signaling pathway sara04916   Melanogenesis sara04918   Thyroid hormone synthesis sara04921   Oxytocin signaling pathway sara04923   Regulation of lipolysis in adipocytes sara04924   Renin secretion sara04925   Aldosterone synthesis and secretion sara04926   Relaxin signaling pathway sara04927   Cortisol synthesis and secretion sara04928   Parathyroid hormone synthesis, secretion and action sara04934   Cushing syndrome sara04935   Growth hormone synthesis, secretion and action sara04970   Salivary secretion sara04971   Gastric acid secretion sara04972   Pancreatic secretion sara04976   Bile secretion sara05012   Parkinson disease sara05030   Cocaine addiction sara05031   Amphetamine addiction sara05032   Morphine addiction sara05034   Alcoholism sara05163   Human cytomegalovirus infection sara05166   Human T-cell leukemia virus 1 infection sara05200   Pathways in cancer sara05207   Chemical carcinogenesis - receptor activation sara05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     101551819 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     101551819 (ADCY5)    04371 Apelin signaling pathway     101551819 (ADCY5)    04072 Phospholipase D signaling pathway     101551819 (ADCY5)    04024 cAMP signaling pathway     101551819 (ADCY5)    04022 cGMP-PKG signaling pathway     101551819 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     101551819 (ADCY5)    04081 Hormone signaling     101551819 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     101551819 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     101551819 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101551819 (ADCY5)    04062 Chemokine signaling pathway     101551819 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     101551819 (ADCY5)    04923 Regulation of lipolysis in adipocytes     101551819 (ADCY5)    04912 GnRH signaling pathway     101551819 (ADCY5)    04913 Ovarian steroidogenesis     101551819 (ADCY5)    04915 Estrogen signaling pathway     101551819 (ADCY5)    04914 Progesterone-mediated oocyte maturation     101551819 (ADCY5)    04921 Oxytocin signaling pathway     101551819 (ADCY5)    04926 Relaxin signaling pathway     101551819 (ADCY5)    04935 Growth hormone synthesis, secretion and action     101551819 (ADCY5)    04918 Thyroid hormone synthesis     101551819 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     101551819 (ADCY5)    04916 Melanogenesis     101551819 (ADCY5)    04924 Renin secretion     101551819 (ADCY5)    04925 Aldosterone synthesis and secretion     101551819 (ADCY5)    04927 Cortisol synthesis and secretion     101551819 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101551819 (ADCY5)    04270 Vascular smooth muscle contraction     101551819 (ADCY5)   09154 Digestive system    04970 Salivary secretion     101551819 (ADCY5)    04971 Gastric acid secretion     101551819 (ADCY5)    04972 Pancreatic secretion     101551819 (ADCY5)    04976 Bile secretion     101551819 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     101551819 (ADCY5)    04727 GABAergic synapse     101551819 (ADCY5)    04725 Cholinergic synapse     101551819 (ADCY5)    04728 Dopaminergic synapse     101551819 (ADCY5)    04726 Serotonergic synapse     101551819 (ADCY5)    04723 Retrograde endocannabinoid signaling     101551819 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101551819 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     101551819 (ADCY5)    04213 Longevity regulating pathway - multiple species     101551819 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     101551819 (ADCY5)    04714 Thermogenesis     101551819 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101551819 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     101551819 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101551819 (ADCY5)    05163 Human cytomegalovirus infection     101551819 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     101551819 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     101551819 (ADCY5)    05031 Amphetamine addiction     101551819 (ADCY5)    05032 Morphine addiction     101551819 (ADCY5)    05034 Alcoholism     101551819 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     101551819 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     101551819 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     101551819 (ADCY5) Enzymes [BR:sara01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      101551819 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  101551819 NCBI-ProteinID:  XP_004606726 LinkDB All DBs Position Unknown AA seq 1021 aa AA seqDB search MLMAVLVLVCLVMLAFHAARPPVQLPYLGVLAAAVGVILVMAVLCNRAAFHQDHMGLACY ALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLA IALRTNAQDRFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQR ENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLAS QCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMD MIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGR IHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILNCTQKRKEEKAMIAKMNRQR TNSIGHNPPPWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGRA IDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIV PHSLFMLSFYLACFLLLTSVVFVSVIYSCVKLFPSRLQTLSRKIVRSKMNSTLVGVFTII LVFLSAVVNMFMCNSGDLSGCLAEEHNISSAQVTACHVVFSAVNYSLADEQGFCGSPRPT CNFPEYFTYSVLLSLLACSVFLHISCIGKLALMLAIELIYVLIVEVPSVSLFDNADLLVT ANAIDFSSSNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKL QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANF SEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFKQLEKIKTIGSTYMAASGLNDSTY DKAGKSHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWG NTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPL S NT seq 3066 nt NT seq  +upstreamnt  +downstreamnt atgctcatggccgtgctggtgctcgtgtgcctcgtcatgctggccttccacgccgcgcgg ccccccgtccagctgccctacctgggcgtgctggcggccgccgtgggggtcatcctggtc atggccgtgctctgcaaccgcgccgccttccaccaggaccacatgggcctggcctgctac gcgctcatcgccgtggtgctggcggtccaggtggtgggcctgctgctgccccagccgcgc agcgcctccgagggcatctggtggaccgtgttcttcatctacaccatctacacgctgctg cccgtgcgcatgcgggccgccgtcctcagcggggtcttgctgtccgcgctccacctggcc atcgccctgcgcaccaacgcccaggatcgcttcctgctcaagcagctcgtctccaacgtg ctcatcttctcctgcaccaacatcgtgggcgtctgcacccactaccccgcggaggtgtcg cagagacaggccttccaggagacccgggagtgcatccaggcacggctgcactcgcagcgg gagaaccagcagcaggagcggctgctgctgtctgtcctgccccgccatgttgccatggag atgaaggcagacatcaacgccaagcaggaggatatgatgttccacaagatctacatccag aagcacgacaatgtgagcatcctgtttgctgacatcgagggcttcacgagtctggcatcc cagtgcacggcccaggaactggtcatgacactcaacgagctcttcgcccgcttcgacaag ctggctgcggagaatcactgtctgcggatcaagatcctgggggactgctactactgcgtc tcggggctgcccgaggccagggccgaccacgcccactgctgcgtggagatgggcatggac atgatcgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaacatgcgcgtg ggaatccacagcgggcgcgtacactgcggtgtccttggtctcaggaagtggcagttcgac gtctggtctaacgacgtcacgctggccaaccacatggaggctggaggcaaagcagggcgc atccacatcaccaaggccacgctcaactacctgaacggggactacgaggtggagccgggc tgcgggggcgagcgcaacgcctacctcaaggagcacagcatcgagaccttcctcatcctc aactgcacccagaagcggaaagaagagaaggctatgatcgccaagatgaatcgccagaga accaactccatcgggcacaacccgccgccctggggggccgagcgccccttctacaaccac ctgggtggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaaggac aagaacgctcaggaaagtgcaaaccctgaggatgaagtggatgagtttctgggccgtgcc atcgacgccaggagcatcgacaggctgcgctccgagcacgtgcgcaagttcctgctgacc ttcagggagcctgacctagagaagaagtactccaagcaggtggatgaccgattcggtgcc tacgtggcgtgtgcctcgctcgtcttcctcttcatctgctttgtccagatcaccattgtg ccacactctctcttcatgctgagtttctacctggcctgtttcctgctgctgacctcagtg gtgttcgtgtctgtgatctactcctgtgtgaagctgttccccagccggctgcagaccctg tccaggaagattgtgaggtccaagatgaacagcactctggttggggtgttcaccatcatc ctggtgttcctgtcggctgtcgtcaacatgttcatgtgcaactccggggacctgtcgggc tgcctggcagaggagcacaacatcagcagtgcccaggtcaccgcctgccacgtggtgttc tcagctgtcaactacagcctggccgacgagcagggcttctgcggcagcccccggcccacc tgcaacttccccgagtacttcacctacagtgtgctgctcagcctgctggcctgctctgtg ttcctgcacatcagctgcatcgggaagctggcgctcatgctggccatcgagctcatctac gtgctcatcgtggaggtgcccagcgtctcgctcttcgacaacgccgacctgctggtcacc gccaacgccatagacttcagcagcagcaacaacaacgggacctcccagtgccctgagcat gccaccaaggtggcgctgaaggtggtgacgcccatcatcatctccgtgttcgtgctggcc ctttacctgcacgcccagcaggtggagtccactgcccgccttgacttcctctggaaactc caggccacggaggagaaggaggagatggaggagttgcaggcctacaaccggcggctgctg cacaacatcctgcccaaggacgtggctgcgcacttcctggcgcgcgagcggcgcaacgac gagctgtactaccagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaacttc tccgagttctacgtggagctggaggccaacaacgagggcgtcgagtgcctgcggctgctc aacgagatcatcgctgactttgacgagatcatcagcgaggaccgcttcaagcagctggag aagattaaaaccatcggcagcacctacatggctgcctcgggcctcaacgactccacctac gacaaggcgggcaagagccacatcaaggcgctggccgacttcgccatgaagctgatggac caaatgaagtacatcaacgagcactccttcaacaacttccagatgaagatcgggctcaat attggccccgtggtggccggggtgatcggggcacggaagcctcagtacgacatctggggc aacacagtgaatgtggccagccgcatggacagcaccggggtgcccgaccggatccaggtc accacagacatgtaccaggtgctggccgccaacacctaccagctggagtgtcggggtgtg gtgaaggtcaaaggcaagggcgaaatgatgacctacttcctcaacggagggcccccgctc agctag

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