Sorex araneus (European shrew): 101558664 Help Entry 101558664         CDS       T07854                                  Symbol TNF Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism sara  Sorex araneus (European shrew) Pathway sara01523   Antifolate resistance sara04010   MAPK signaling pathway sara04060   Cytokine-cytokine receptor interaction sara04061   Viral protein interaction with cytokine and cytokine receptor sara04064   NF-kappa B signaling pathway sara04071   Sphingolipid signaling pathway sara04150   mTOR signaling pathway sara04210   Apoptosis sara04217   Necroptosis sara04350   TGF-beta signaling pathway sara04380   Osteoclast differentiation sara04612   Antigen processing and presentation sara04620   Toll-like receptor signaling pathway sara04621   NOD-like receptor signaling pathway sara04622   RIG-I-like receptor signaling pathway sara04625   C-type lectin receptor signaling pathway sara04640   Hematopoietic cell lineage sara04650   Natural killer cell mediated cytotoxicity sara04657   IL-17 signaling pathway sara04660   T cell receptor signaling pathway sara04664   Fc epsilon RI signaling pathway sara04668   TNF signaling pathway sara04920   Adipocytokine signaling pathway sara04930   Type II diabetes mellitus sara04931   Insulin resistance sara04932   Non-alcoholic fatty liver disease sara04933   AGE-RAGE signaling pathway in diabetic complications sara04936   Alcoholic liver disease sara04940   Type I diabetes mellitus sara05010   Alzheimer disease sara05014   Amyotrophic lateral sclerosis sara05020   Prion disease sara05022   Pathways of neurodegeneration - multiple diseases sara05132   Salmonella infection sara05133   Pertussis sara05134   Legionellosis sara05135   Yersinia infection sara05140   Leishmaniasis sara05142   Chagas disease sara05143   African trypanosomiasis sara05144   Malaria sara05145   Toxoplasmosis sara05146   Amoebiasis sara05152   Tuberculosis sara05160   Hepatitis C sara05161   Hepatitis B sara05163   Human cytomegalovirus infection sara05164   Influenza A sara05165   Human papillomavirus infection sara05166   Human T-cell leukemia virus 1 infection sara05168   Herpes simplex virus 1 infection sara05169   Epstein-Barr virus infection sara05170   Human immunodeficiency virus 1 infection sara05171   Coronavirus disease - COVID-19 sara05205   Proteoglycans in cancer sara05310   Asthma sara05321   Inflammatory bowel disease sara05322   Systemic lupus erythematosus sara05323   Rheumatoid arthritis sara05330   Allograft rejection sara05332   Graft-versus-host disease sara05410   Hypertrophic cardiomyopathy sara05414   Dilated cardiomyopathy sara05417   Lipid and atherosclerosis sara05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:sara00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101558664 (TNF)    04350 TGF-beta signaling pathway     101558664 (TNF)    04064 NF-kappa B signaling pathway     101558664 (TNF)    04668 TNF signaling pathway     101558664 (TNF)    04071 Sphingolipid signaling pathway     101558664 (TNF)    04150 mTOR signaling pathway     101558664 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101558664 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     101558664 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     101558664 (TNF)    04217 Necroptosis     101558664 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101558664 (TNF)    04620 Toll-like receptor signaling pathway     101558664 (TNF)    04621 NOD-like receptor signaling pathway     101558664 (TNF)    04622 RIG-I-like receptor signaling pathway     101558664 (TNF)    04625 C-type lectin receptor signaling pathway     101558664 (TNF)    04650 Natural killer cell mediated cytotoxicity     101558664 (TNF)    04612 Antigen processing and presentation     101558664 (TNF)    04660 T cell receptor signaling pathway     101558664 (TNF)    04657 IL-17 signaling pathway     101558664 (TNF)    04664 Fc epsilon RI signaling pathway     101558664 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     101558664 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     101558664 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     101558664 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101558664 (TNF)    05170 Human immunodeficiency virus 1 infection     101558664 (TNF)    05161 Hepatitis B     101558664 (TNF)    05160 Hepatitis C     101558664 (TNF)    05171 Coronavirus disease - COVID-19     101558664 (TNF)    05164 Influenza A     101558664 (TNF)    05168 Herpes simplex virus 1 infection     101558664 (TNF)    05163 Human cytomegalovirus infection     101558664 (TNF)    05169 Epstein-Barr virus infection     101558664 (TNF)    05165 Human papillomavirus infection     101558664 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     101558664 (TNF)    05135 Yersinia infection     101558664 (TNF)    05133 Pertussis     101558664 (TNF)    05134 Legionellosis     101558664 (TNF)    05152 Tuberculosis     101558664 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     101558664 (TNF)    05144 Malaria     101558664 (TNF)    05145 Toxoplasmosis     101558664 (TNF)    05140 Leishmaniasis     101558664 (TNF)    05142 Chagas disease     101558664 (TNF)    05143 African trypanosomiasis     101558664 (TNF)   09163 Immune disease    05310 Asthma     101558664 (TNF)    05322 Systemic lupus erythematosus     101558664 (TNF)    05323 Rheumatoid arthritis     101558664 (TNF)    05321 Inflammatory bowel disease     101558664 (TNF)    05330 Allograft rejection     101558664 (TNF)    05332 Graft-versus-host disease     101558664 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     101558664 (TNF)    05014 Amyotrophic lateral sclerosis     101558664 (TNF)    05020 Prion disease     101558664 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     101558664 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101558664 (TNF)    05418 Fluid shear stress and atherosclerosis     101558664 (TNF)    05410 Hypertrophic cardiomyopathy     101558664 (TNF)    05414 Dilated cardiomyopathy     101558664 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101558664 (TNF)    04940 Type I diabetes mellitus     101558664 (TNF)    04936 Alcoholic liver disease     101558664 (TNF)    04932 Non-alcoholic fatty liver disease     101558664 (TNF)    04931 Insulin resistance     101558664 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     101558664 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     101558664 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:sara04052]     101558664 (TNF)    00536 Glycosaminoglycan binding proteins [BR:sara00536]     101558664 (TNF) Cytokines and neuropeptides [BR:sara04052]  Cytokines   Tumor necrosis fators    101558664 (TNF) Glycosaminoglycan binding proteins [BR:sara00536]  Heparan sulfate / Heparin   Cytokines    101558664 (TNF) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  101558664 NCBI-ProteinID:  XP_004621326 LinkDB All DBs Position Unknown AA seq 234 aa AA seqDB search MSTESMIRDVELAEEALPKKEGGPQGSRRCWCLSLFSFVVILGATTLFCLLHFRVIGPQR DEFPDSFPLINPLAQTLRSGSSQFPSDKPVAHVVGKYQVEGKLLWQNRVANTLVANGMEL TDNELVVPSDGLYLIYSQVLFQGQDCPSTHVLLAHSIKRFAVSYQTKVDLLSAIKSPCSR ETPEGSEARPWFEPIYLGGVFHLEKGDRLSAEINLPSYLDLSKTEQVYFGIVAL NT seq 705 nt NT seq  +upstreamnt  +downstreamnt atgagcacagaaagcatgatccgggacgtggaactggctgaggaagcgctccccaagaag gaagggggcccccagggctccaggaggtgctggtgcctcagcctcttctccttcgtcgtc atcttaggagccaccacgctcttctgcctgctgcacttcagggtcatcggccctcagagg gacgagttcccagacagcttcccgctcatcaaccctctggcccagaccctgagatcagga tcatcccagttcccaagtgataagcccgtagcccatgttgtaggtaagtaccaagttgaa ggaaaactcctgtggcagaaccgagtggccaataccctcgtggccaacggcatggagctg acagacaacgagctggtggtgccctccgatgggctgtacctcatctactcccaggtcctc ttccagggccaagactgcccttccacccacgtgctcctcgcccacagcatcaagcgcttt gctgtctcctaccagaccaaggtagacctcctctccgccatcaagagtccctgctccagg gagaccccagagggctcggaggcgaggccctggtttgagcccatctatttggggggggtc ttccacctggagaagggcgaccggctcagcgcggagatcaatctgcccagctatctggac ctttccaagaccgagcaggtctacttcgggatcgttgccctgtag

DBGET integrated database retrieval system