Streptomyces argyrophylli: HKX69_04515
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Entry
HKX69_04515 CDS
T09378
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
sarg
Streptomyces argyrophylli
Pathway
sarg00909
Sesquiterpenoid and triterpenoid biosynthesis
sarg01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
sarg00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
HKX69_04515 (shc)
Enzymes [BR:
sarg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
HKX69_04515 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
HKX69_04515 (shc)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Prenyltrans
PGM1_C
Motif
Other DBs
NCBI-ProteinID:
QJS08876
UniProt:
A0A6M4PGV3
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Position
complement(1047160..1049190)
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AA seq
676 aa
AA seq
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MTATTDGSTGATLPSRAAAASDTTLTTPEAAGVQEAAARAARRATDFLLSRQDSEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEETTRAAAKFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKASAWVRERGGIAASRVFTRIWLALFGWWKWEDLPELPPELIW
FPTWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPARPNPARPLAPLAS
WDGAFQRIDKALHQFRKVAPRRLRKAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGLPVDHPQ
LVKAADWMLGEEIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHD
PERVDKAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQEPNGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVVWLESVQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGEKDSK
AVERGIQWLAETQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
KLLARTKAAASRATGS
NT seq
2031 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggggcgaccttgccgtcccgggctgccgcggcc
agcgacaccaccctcaccactcccgaggcggccggggtacaggaagccgccgcgcgcgcc
gcacgacgcgccaccgacttcctgctctcccggcaggactcggagggctggtggaagggc
gacctggagaccaacgtcaccatggacgccgaagacctgctgctccggcagttcctgggc
atccaggacgaggagaccacgcgggccgccgcgaagttcatccgcggcgagcagcgtgag
gacggcacctgggccaccttctacggcggccccggcgaactgtccaccaccatcgaggcg
tacgtcgccctgcgtctggccggtgacgcgcccgacgccccgcacatggcgaaggcgtcc
gcctgggtccgcgaacgcggtggcatcgccgcctcccgcgtgttcacccggatctggctc
gccctgttcggctggtggaagtgggaggacctgcccgagctgcccccggagctgatctgg
ttccccacctggatgccgctcaacatctacgacttcggatgctgggcccggcagaccatc
gtcccgctcaccatcgtctcggccaagcgcccggtgcgccccgcgcccttcgcgctggac
gaactgcacaccgacccggcccggcccaacccggcccgccccctggccccgctggccagc
tgggacggcgccttccagcgcatcgacaaggcgctgcaccagttccgcaaggtcgccccg
cgcaggctgcgcaaggcggcgatgaacgcggcggcccgctggatcatcgagcggcaggag
aacgacggctgctggggcggcatccagcccccggccgtgtactcggtcatcgccctgcac
ctgctcggctacgacctccagcaccccgtgatgcgtgagggcctcgcctcgctggaccgt
ttcgccgtctggcgcgaggacggcgcccgcatgatcgaggcctgccagtccccggtctgg
gacacctgcctcgccacgatcgccctcgtggacgccggtctgcccgtcgaccacccgcaa
ctggtcaaggcggccgactggatgctcggcgaggagatcgtccgccccggcgactggtcc
gtgaagcgtcccggactgccgccgggcggctgggcgttcgagttccacaacgacaactac
ccggacatcgacgacaccgccgaggtcgccctcgcgctgcgccgggtccggcaccacgac
cccgagcgcgtcgacaaggcgatcgggcgggccgtgcgctggaacctcggcatgcagtcg
aagaacggcgcctggggcgccttcgacgtcgacaacaccagcccgtttcccaaccggctg
ccgttctgcgacttcggcgaggtcatcgacccgccgtccgcggacgtcaccgcgcacgtc
gtggagatgctcgccgccgagggactcgcccacgacccgcgcacccggcgcggcatcgac
tggctgctcgccgaacaggagcccaacggctcgtggttcggccgctggggcgtcaactac
atctacggcacgggctcggtggtgcccgcgctgaccgcggccggactgcccggctcgcac
ccggcgatccggcgggccgtggtctggctggagagcgtccagaacgacgacggcggctgg
ggcgaggacctgcgctcctacaagtacgtcaaggagtggagcggccggggcgcgtccacc
gcctcgcagaccgcgtgggcgctgatggcgctgctcgcggcgggggagaaggactccaag
gcggtcgagcgcggcatccagtggctggccgagacccagcgcgaggacggcacctgggac
gagccgtacttcaccggcaccggcttcccctgggacttctccatcaactaccacctgtac
cgccaggtgttcccgctcaccgcgctcggccgctacctgcacggcgaccccttcgagcgc
aagctgctcgccaggaccaaggcggccgcgtcacgggcgacggggagctga
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