Streptomyces argyrophylli: HKX69_11265
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Entry
HKX69_11265 CDS
T09378
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sarg
Streptomyces argyrophylli
Pathway
sarg00020
Citrate cycle (TCA cycle)
sarg00630
Glyoxylate and dicarboxylate metabolism
sarg00785
Lipoic acid metabolism
sarg01100
Metabolic pathways
sarg01110
Biosynthesis of secondary metabolites
sarg01120
Microbial metabolism in diverse environments
sarg01200
Carbon metabolism
sarg01210
2-Oxocarboxylic acid metabolism
Module
sarg_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sarg_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sarg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
HKX69_11265
00630 Glyoxylate and dicarboxylate metabolism
HKX69_11265
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HKX69_11265
Enzymes [BR:
sarg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
HKX69_11265
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
HKX69_11265
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
HKX69_11265
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
HKX69_11265
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QJS10031
UniProt:
A0A6M4PGA9
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All DBs
Position
2583445..2587257
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AA seq
1270 aa
AA seq
DB search
MSPQSPSNSSISTDDQAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPG
APATPAPAGTAATGAAETPTTAPQARPAAPAPQAAAPAAPAAEKPAAAPAQAPAPAPAPA
AKTPAPAKPAQPPQAPAQPKAKPAEAPEGPELVTLRGPAAAVAKNMNASLELPTATSVRA
VPVKLLFDNRIVINNHLKRARGGKISFTHLIGFAMVQAIKAMPSMNWSFGEKDGKPTLVK
PPHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTG
VTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTS
TYDHRVIQGAASGEFLRQVANLLLGENGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTK
AARVFELIHSYRVRGHVMADTDPLEYKQRKHPDLDITEHGLTLWDLERDFAVGGFAGKSM
MKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHAKMEREEQLRILRRLNAA
EAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANI
VGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLETVD
PVIEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHI
VINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKD
VVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQ
DYQGQLEKVFTEVREAVTTQQATGPAPDPQADFPVAVNTAISSEVVKRIAESQVNIPDSF
HVHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLEGTPVRLSGQDSQRGTFGQRHAV
LIDRETGEEYTPLQYLAEDQARYNVYNSLLSEYAVMGFEYGYSLARPDALVMWEAQFGDF
VNGAQTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARVERFLQLCAQNNMTVA
MPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTSGQFRPVIGDTAAD
PAAVRKVVFVAGKLYYDLEAERQKRGVTDTAIIRIERLYPLPGAEIQAEVNKYPNAEKYL
WAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQ
EQLVREVFEA
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctccaccgacgaccaagccgggaagaac
cccgcagcagcgttcggtgcgaacgagtggctcgtcgacgagatctatcagcagtacctc
caggacccgaattcggtagaccgtgcctggtgggacttcttcgccgattacaagccgggt
gctcctgccaccccggctccggcgggtactgcggccacgggggccgcagagacccccacc
acggccccgcaggcccggcccgcggccccggccccccaggccgccgccccggccgccccc
gcggctgagaagcccgccgccgctcccgcccaggccccggccccggccccggcccccgcg
gcgaagacccccgccccggccaagccggcgcagcccccacaggcgcccgctcagcccaag
gcgaagcccgccgaggcccccgagggcccggagctggtcacgctgcgcggtccggccgcc
gccgtcgccaagaacatgaacgcctccctggagctgccgaccgccacctcggtccgcgcc
gtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcc
cggggcgggaagatctccttcacgcacctgatcggcttcgcgatggtgcaggccatcaag
gccatgccgtcgatgaactggtcgttcggcgagaaggacggcaagccgaccctcgtcaag
ccgccgcacgtcaacctcggcctggccatcgacctggtgaagccgaacggtgaccgccag
ctcgtcgtggccgccatcaagaaggccgagacgctgaacttcttcgagttctggcaggcc
tacgaggacatcgtccgccgcgcccgcgacggcaagctgacgatggacgacttcaccggt
gtcacggtctccctgaccaaccccggcggcctcggcaccgtccactccgtgccgcgcctc
atgcccggccagtccgtgatcatgggcgtcggctccatggactacccggcggagttccag
ggcaccagccaggacaccctgaacaagctcggcatctcgaaggtcatgacgctcacgtcg
acctacgaccaccgggtcatccagggcgccgcctccggcgagttcctccgccaggtcgcc
aacctgctgctcggcgagaacggcttctacgacgacatcttcgaggcgctgcgcatcccc
tacgagccggtccgctggctcaaggacatcgacgccagccacgacgacgacgtcaccaag
gccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgac
accgacccgctggagtacaagcagcgcaagcaccccgacctggacatcaccgagcacggg
ctcaccctgtgggacctggagcgcgacttcgcggtcggcggcttcgccggcaagtcgatg
atgaagctgcgtgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcatc
gagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgcgtcgagcgc
ccgcacgccaagatggagcgcgaggagcagctgcggatcctgcgccggctgaacgccgcc
gaggccttcgagacgttcctgcagacgaagtacgtcggccagaagcgcttctcgctggag
ggcggcgagtccgtcatcccgctgctcgacgcggtgatcgactccgccgccgagtcccgc
ctggacgaggtcgtcatcggcatggcccaccgcggccgcctgaacgtcctcgccaacatc
gtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcg
atgcacggctccggcgacgtcaagtaccacctgggcgccgagggcaccttcaccggtctg
gacggcgagcagatcaaggtctcgctggccgccaacccctcccacctggagacggtcgac
ccggtcatcgagggcatcgcccgcgccaagcaggacatcatcaacaagggcgggacggac
ttcaccgtgctgcccgtcgccctgcacggcgacgcggccttcgcgggccagggcgtggtg
gccgagaccctgaacatgtcgcagctgcgcggttaccgcaccggcggcacggtccacatc
gtcatcaacaaccaggtcggcttcaccgcggcccccgagtcctcgcgttcctccatgtac
gcgacggatgtggcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccg
gaggccgtggtccgcgtcgcgcgtctggccttcgagttccgccaggcgttcaacaaggac
gtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggcc
ttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtac
accgagtccctgatcggtcgcggcgacatcaccctggaagaggccgagcaggccctgcag
gactaccagggccagctggagaaggtcttcacggaggtccgcgaggccgtcacgacccag
caggccaccggtcccgccccggacccgcaggcggacttcccggtggcggtgaacaccgcg
atctcctcggaggtcgtcaagcgcatcgccgagtcccaggtcaacatcccggactccttc
cacgtccacccgcgcctgctgccccagctgcagcgccgcgcggcgatggtcgaggacggc
acgatcgactggggcatgggcgagaccctcgcggtcggctccctgctgctggagggcacc
ccggtccggctgtccggccaggactcccagcgcggcaccttcggccagcgccacgcggtc
ctcatcgaccgcgagacgggcgaggagtacaccccgctgcagtacctcgccgaggaccag
gcgcgctacaacgtctacaactccctgctgtccgagtacgcggtcatgggcttcgagtac
ggctactcgctcgcccgccccgacgcgctcgtgatgtgggaggcgcagttcggcgacttc
gtcaacggcgcccagacggtggtcgacgagtacatctcggcggcggagcagaagtggggc
cagacgtccggcgtcaccctgctcctgccccacggctacgagggccagggcccggaccac
tcctcggcccgtgtcgagcggttcctccagctctgcgcgcagaacaacatgacggtcgcc
atgccgaccctgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcac
cacaagccgctggtggtcttcaccccgaagtcgatgctgcgcctgaaggccgccgcgtcg
aagacggaggagttcacctcgggtcagttccgtcccgtcatcggggacacggcggcggac
ccggccgcggtccgcaaggtcgtgttcgtggccggcaagctgtactacgacctcgaggcc
gagcggcagaagcggggcgtgacggacaccgcgatcatccgcatcgagcggctgtacccg
ctgccgggcgcggagatccaggcggaggtcaacaagtacccgaacgccgagaagtacctg
tgggcgcaggaggagccggcgaaccagggtgcgtggccgttcatcgcgctcaacctgatc
gaccacctggacctggcggtcggcgcggacgtcccgcacggcgagcgcctgcggcgcatc
tcgcgtccgcactcctcgtccccggcggtcggctccgcgaagcggcaccaggcggagcag
gagcagctggtgcgtgaggtcttcgaggcgtag
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