Streptomyces calvus: CD934_03265
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Entry
CD934_03265 CDS
T06819
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
sast
Streptomyces calvus
Pathway
sast00909
Sesquiterpenoid and triterpenoid biosynthesis
sast01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
sast00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
CD934_03265 (shc)
Enzymes [BR:
sast01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
CD934_03265 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
CD934_03265 (shc)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
QDI67792
UniProt:
A0A514JLB5
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Position
complement(801817..803877)
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AA seq
686 aa
AA seq
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MTATTDGSTGAALPPRVTAASENDTDIPEAAGVPDIAARAVRRATDFLLSRQDDQGWWKG
DLETNVTMDAEDLLLRQFLGIRDEDTTRAAALFIRGEQREDGTWATFHGGPGELSTTIEA
YVALRLAGDPPDAPHMAKASAWVREQGGIAASRVFTRIWLALFGWWRWEDLPELPPELIW
FPSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPRHPNPPRPLAPPLS
WDGAFQRLDRTLHALRRAVPRRLRAAAMHTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLNHPVMRAGLESLDRFAVWREDGARMVEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEQIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHD
PERLDNAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRAVQWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGLPGSH
PAIRRAVAWLESVQNDDGGWGEDLRSYRHAREWAGRGTSTASQTAWALMALLAAGERESR
AVERGVEWLAATQREDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAA
RPAAASARAEPTAAGVDLPLAEAKGS
NT seq
2061 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggggctgccctgccgccccgcgtgaccgcggcc
agcgaaaacgacaccgacatccccgaggcggccggggttcccgacatcgccgcccgcgcc
gtgcggcgcgccaccgacttcctgctgtcccggcaggacgaccagggctggtggaagggc
gacctcgagaccaacgtcacgatggacgccgaggacctgctgctgcgccagttcctcggc
atccgcgacgaggacaccacccgcgccgccgccctgttcatccggggcgagcagcgcgag
gacggcacctgggccaccttccacggcggccccggggaactctccaccaccatcgaggcg
tacgtcgcgctgcgcctggccggcgacccgcccgacgccccgcacatggcgaaggcctcc
gcctgggtccgcgagcagggcggcatcgccgcctcccgggtcttcacccggatctggctc
gccctgttcggctggtggcggtgggaggacctgccggaactgccgcccgagctgatctgg
ttcccgtcctgggtgccgctcaacatctacgacttcggctgctgggcccggcagaccatc
gtcccgctgacgatcgtctccgcgaaacggccggtgcgccccgccccgttcccgctggac
gaactgcacaccgacccccgccaccccaaccctccccgcccgctcgccccgcccctgagc
tgggacggcgccttccagcggctggacaggacactgcacgccctgcgccgggcggtcccg
cgccggctgcgcgcggcggccatgcacaccgccgcccggtggatcatcgagcggcaggag
aacgacggctgctggggcggcatccagccgcccgccgtctactcgatcatcgcgctgcac
ctgctcggctacgacctgaaccatcccgtgatgcgcgccggcctggagtccctggaccgg
ttcgccgtgtggcgcgaggacggcgcccggatggtggaggcctgccagtccccggtgtgg
gacacctgcctcgccaccatcgcgctggccgacgccggactgcccgccgaccatccgcaa
ctggtcaaggccgccgactggatgctgggcgagcagatcgtacggcccggcgactggtcc
gtgcgccggccccaactgccgcccggcggctgggcgttcgagttccacaacgacaactat
cccgacatcgacgacaccgccgaggtggtcctcgcgctgcgccgggtcaagcaccacgac
cccgaacggctggacaacgccatcgggcgcggcgtgcgctggaacctcggcatgcagtcg
aggaacggcgcctggggcgccttcgacgtcgacaacaccagcccgttccccaaccggctg
ccgttctgcgacttcggcgaggtcatcgacccgccgtcggccgacgtcaccgcgcacgtc
gtggagatgctcgccgtggaagggctcgcccacgacccgcgcacccggcgcgccgtccag
tggctgctcgccgagcaggagcccgacggctcctggttcggacgctggggcgtgaactac
ctgtacggcaccggctccgtggtgcccgccctgaccgccgccggcctgcccggctcgcac
ccggcgatccgccgggccgtcgcctggctggagtcggtgcagaacgacgacggcggctgg
ggcgaggacctgcgctcctaccgccacgcccgggaatgggccggccgcgggacctccacc
gcctcgcagaccgcgtgggcgctgatggcgctgctggcggcgggggagagggagtccagg
gccgtcgagcgcggcgtcgagtggctggcggccacccagcgcgaggacggctcctgggac
gagccgcacttcaccggcaccggcttcccctgggacttctccatcaactaccacctctac
cggcaggtcttcccgctcaccgcgctcggccggtacgtccacggggagcccttcgccgca
cggcccgccgcggcgagcgcccgcgccgagccgacggccgcgggcgtggacctgccgctc
gccgaggcgaagggcagctga
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