Streptomyces calvus: CD934_10545
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Entry
CD934_10545 CDS
T06819
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sast
Streptomyces calvus
Pathway
sast00020
Citrate cycle (TCA cycle)
sast00630
Glyoxylate and dicarboxylate metabolism
sast00785
Lipoic acid metabolism
sast01100
Metabolic pathways
sast01110
Biosynthesis of secondary metabolites
sast01120
Microbial metabolism in diverse environments
sast01200
Carbon metabolism
sast01210
2-Oxocarboxylic acid metabolism
Module
sast_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sast_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sast00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CD934_10545
00630 Glyoxylate and dicarboxylate metabolism
CD934_10545
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CD934_10545
Enzymes [BR:
sast01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CD934_10545
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CD934_10545
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CD934_10545
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CD934_10545
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QDI69088
UniProt:
A0A514JQP8
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All DBs
Position
2593635..2597447
Genome browser
AA seq
1270 aa
AA seq
DB search
MSPQSPSNSSISPDTDQAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAPATSAPAGNAATAAAGTTTTAQPAAQARPAAPAPAAAQPAAAAPAAQPAAKAAPAPAP
AAPAKAAAPAAAKPAAAKAEAEPAGEAKTGPEQVTLRGPSAAVAKNMDASLELPTATSVR
AVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAKVDGKPTLV
KPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDNKLTMDDFT
GVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLT
STYDHRVIQGAASGEFLRQVANLLLGENGFYDEIFEALRIPYEPVRWLKDIDASHDDDVT
KAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDIVEHGLTLWDLEREFAVGGFAGKS
LMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRIERSHTKPEREEQLRILRRLNA
AEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLAN
IVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAV
DPVLEGVARAKQDIIGKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVH
IVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNK
DVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQAL
QDYQGQLEKVFTEVREATSQPSSVESPDPQAEFPVAVNTAVTTEIVKRIAESQVNIPDHI
TVHPRLLPQLQRRAAMVEDGTIDWGMGETLAFGSLLLEGVPVRLAGQDSQRGTFGQRHAV
IIDRSTGEEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDF
VNGAQTVVDEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVA
MPTSPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDASVD
PAAVKKVVFTAGKVYYDLEAERRKRGATDTAIIRIERLYPLPGAELQAEIKKYPNAEKYL
WAQEEPANQGAWPFIALNLIDHLDLAVGADLPHAERLRRISRPHSSSPAVGSAKRHQAEQ
EQLVREVFEA
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcccccgacaccgaccaagcgggcaag
aaccccgctgcggcgttcggtgccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaactcggtggaccgagcctggtgggacttcttcgccgactacaagccg
ggcgctcctgcgacctcggctccggcgggtaacgcggccacggctgccgcggggaccacc
accacggcccagccggccgctcaggcccggcccgccgcgcccgccccggcggccgcacag
cccgctgccgccgcacccgccgcacagccggccgccaaggctgccccggcgccggctccc
gccgctccggcgaaggccgccgcgcccgccgccgccaagccggccgccgcgaaggccgag
gccgagcccgccggcgaggccaagaccggccccgagcaggtgacgctgcgcggcccgtcc
gccgccgtcgcgaagaacatggacgcctcgctggagctgcccacggccacgtccgtgcgc
gcggtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctgaagcgg
gcgcgtggcgggaagatctccttcacgcacctcatcggctacgccatggtccaggccatc
aaggcgatgccgtcgatgaactactcgttcgcgaaggtggacggcaagccgacgctggtc
aagccggagcacgtcaacctcggtctcgccatcgacctggtcaagcccaacggcgaccgc
cagctggtcgtcgcggcgatcaagaaggccgagacgctgaacttcttcgagttctggcag
gcctacgaggacatcgtccgtcgcgcccgcgacaacaagctgacgatggacgacttcacc
ggcgtcacggtctccctgaccaaccccggcggcctcggcaccgtccactccgtgccgcgc
ctgatgcccggccagtcggtgatcatgggcgtcggctccatggactacccggcggagttc
cagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatgacgctcacc
tcgacctacgaccaccgggtgatccagggcgccgcctccggcgagttcctgcgccaggtc
gccaacctgctgctcggcgagaacggcttctacgacgagatcttcgaggcgctgcgcatc
ccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcacc
aaggccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatggcc
gacaccgacccgctggagtaccgccagcgcaagcaccccgacctggacatcgtcgagcac
ggcctcaccctgtgggacctggagcgcgagttcgccgtcggcggcttcgccggcaagtcc
ctgatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggc
gtcgagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgcatcgag
cgctcgcacaccaagccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgcc
gcggaggccttcgaaaccttcctgcagacgaagtacgtcggccagaagcgtttctccctg
gagggcggcgagtccgtcatcccgctgctcgacgcggtgctggactcggccgccgagtcc
cgcctggacgaggtcgtcatcggcatggcccaccgcggccggctcaacgtcctcgccaac
atcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaag
tcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggcaccttcaccggc
ctggacggcgagcagatcaaggtctccctggtcgccaacccctcgcacctggaggcggtc
gacccggtcctggagggcgtcgcccgcgccaagcaggacatcatcggcaagggcggcacg
gacttcacggtgctgccggtggcgatccacggcgacgcggccttcgcgggccagggcgtg
gtggccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccac
atcgtcatcaacaaccaggtcggcttcaccgcggcccccgagtcctcgcgttcctccatg
tacgcgacggacgtggcccgcatgatcgaggccccgatcttccacgtgaacggcgacgac
ccggaggcggtggtgcgcgtcgcgcgcctggccttcgagttccgccaggcattcaacaag
gacgtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccg
gccttcacgcagccgctgatgtacgacctgatcgacaagaagcgctcggtacgcaagctc
tacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggccgagcaggcgctg
caggactaccagggccagctggagaaggtcttcaccgaggtccgcgaggccacctcgcag
ccgtcctccgtggagtccccggacccgcaggccgagttcccggtcgccgtgaacaccgcg
gtgaccacggagatcgtcaagcggatcgccgagtcccaggtcaacatccccgaccacatc
accgtgcacccgcgtctgctgccgcagctgcagcgccgtgcggcgatggtcgaggacggc
accatcgactggggcatgggcgagacgctcgccttcggttcgctgctcctcgagggcgtc
ccggtccgcctggccggccaggactcccagcgcggcaccttcggccagcgccacgcggtc
atcatcgaccgcagcacgggcgaggagtacacgccgctgcagtacctctccgaggaccag
gcacggctgaacgtctacaactccctgctgtccgagtacgcggcgatgggcttcgagtac
ggctactcgctggcccgcccggacgcgctcgtgctgtgggaggcgcagttcggtgacttc
gtcaacggcgcgcagacggtcgtggacgagttcatctcctcggccgagcagaagtgggcc
cagacctccggtgtggtcctgctcctcccgcacggctacgagggccagggcccggaccac
tcctcggcccgcccggagcggttcctgcagctgtgcgcgcagaacaacatgacggtcgcg
atgccgacgtcgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcac
cacaagccgctggtcgtcttcacgccgaagtcgatgctgcgcctgaaggccgcggcctcg
aaggcggaggagttcaccacgggccagttccgcccggtcatcggcgacgcctcggtcgac
ccggccgccgtcaagaaggtcgtcttcaccgccggcaaggtctactacgacctggaggcc
gagcggcgcaagcgcggcgcgaccgacacggcgatcatccgcatcgagcgcctgtacccg
ctgccgggtgccgagctccaggcggagatcaagaagtacccgaacgccgagaagtacctg
tgggcgcaggaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatc
gaccacctcgacctggcggtcggtgccgacctcccgcacgccgagcgtctgcgccgcatc
tctcggccgcacagctcgtccccggcggtcggctcggccaagcgccaccaggccgagcag
gagcagctggtgcgtgaggtcttcgaggcgtaa
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