Sylvia atricapilla (blackcap): 136358855
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Entry
136358855 CDS
T10263
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
sati Sylvia atricapilla (blackcap)
Pathway
sati00270
Cysteine and methionine metabolism
sati00480
Glutathione metabolism
sati01100
Metabolic pathways
sati01240
Biosynthesis of cofactors
sati04216
Ferroptosis
Module
sati_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
sati00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
136358855 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
136358855 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
136358855 (GCLC)
Enzymes [BR:
sati01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
136358855 (GCLC)
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
136358855
NCBI-ProteinID:
XP_066171043
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All DBs
Position
3:complement(23475165..23511823)
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETRRYAEHVRRHGIIQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLILCGEEVVQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGKPYGGTMSDFNTV
QDNMRKRRQEAASMLKENEAVCTVTSFPRLGCPGFTLPEYKPTPVEEGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKASKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGSAQNGTGTDTEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEINY
SLMWKCNQIAQGQAECPELLGVGFNKKQSGNKTDSLE
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggtacgcggag
cacgtgcggaggcacggcatcatccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtgctcaagtggggagacgaggtggaatatatgttggtaaaattcgaccat
gaaaataagaaagtgcgtttgatactctgtggtgaagaagttgttcagacactgcaagac
aagggagagaaggtaaaccccaatcacccaacactctggagaccggaatatggaagttac
atgattgaaggaacgcctggaaagccatatgggggaaccatgtctgatttcaacactgtg
caagacaacatgaggaaaagacggcaagaggctgcttctatgctcaaagaaaatgaggct
gtttgcacagtgacatcatttccaaggttagggtgtcctgggtttacactgccggaatat
aagccaacaccagtagaagaaggagcttcaaaatccctcttttttccagatgaagccatc
aataaacatcctagatttagtacactgaccagaaacattcgacaccgaagaggagagaag
gttgtgataaatgtaccaatatttaaagataagaacacgccatcgccttttattgagaca
tttcctaatgatgatggagaagcagcaaaggcatctaagccagactacatatatatggat
gctatgggttttggaatgggaaactgttgtctccaggtaacatttcaggcttgcagcatt
tccgaagcaaggtatctctatgatcagctagcaacgatttgtcccattgtgatggcgttg
agtgctgcatctccattctacagaggctacgtgtctgacattgactgtcgctggggagtg
atctctgcttctgtggatgatcgcacgcgggaggagagaggcctggagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagaccca
ctgactttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
aatattcagtctacaaactggcagacaatgaggtttaagccaccacctccaaattcagat
attggatggagagtggaattcagacctatggaggtccagttaacagactttgaaaactct
gcatatgttgtgtttgtggtattgctaaccagagtgattctatcatataaactggatttt
ctcattcctttgtccaaggtggatgaaaacatgaaggtggcccagaaaagagatgctgta
cgacagggaatgttttacttcagaaaagatatatgcaaaggtggaaatgctgttgtggat
ggatgtggctctgcacagaatgggacaggcaccgacacagaagagtatacgttaatgagc
attgatacaattatcaatgggaaggaaggagtctttcctggtttgatcccaattttgaat
tcctatcttgaaaacatggaagtggatgtcgacacaagatgcaccatcctaaactatctg
aagctaataaaaaagagagcctctggagaattaatgacagttgctcgatggatgagggag
ttcatcgcacagcatccggactacaagcaagacagtgtgataactgatgaaattaattac
agccttatgtggaaatgcaaccaaatagctcaaggccaggcagagtgtcctgaactattg
ggggtaggatttaataagaaacaaagtggaaacaaaactgactctttggaataa
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