Sylvia atricapilla (blackcap): 136359138 Help Entry 136359138         CDS       T10263                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism sati  Sylvia atricapilla (blackcap) Pathway sati04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:sati00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     136359138 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:sati03036]     136359138 (SYNE1) Chromosome and associated proteins [BR:sati03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     136359138 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Motif Other DBs NCBI-GeneID:  136359138 NCBI-ProteinID:  XP_066171588 LinkDB All DBs Position 3:complement(58187648..58473860) Genome browser AA seq 8803 aa AA seqDB search MASSRLAARSRDIANVMQRLQDEQESVQKRTFTKWINTHLAKRNPPMLVNDLFEDIKDGV MLIALLEVLSGQKLPCEQGRQLKRIHWVANIGTALKFLEGRRIKLVNINSTDIADGRPSI VLGLVWTIILYFQIEELTSNLPQLQPLSSSASSVESVVSSETASPPSKRKVVTKVQGSAR KALLKWLQYTAAKQVGIEIKDFGQSWRSGVAFHSVIHAIRPDLVDMEKVRGRSNRENLEE AFTIAEAELGIPRLLDPEDVDVEKPDEKSVMTYVAQFLKYYPDPHHTVTDVPENDKEDRL VLRDLKVWAEQFERDIARAQVAETSLQEKYQSFKHFRVQYEVKRKQFELATQSVRKDGKL SLDQAVVKQAWERVTSRMLDWHIHLDKSLPAPLGTIGAWLYRAEAALREEVAIQQAHEET ANTIHRKLEQHKDLLKNIDGHKKAFHEIHRTRSVNGVPVPHDQLEDMADRFNFVVSSSEL HLLKMEFLELKYRLLSLLVFAESKLKSWIIKYGRRESVELLLQNYISVIENSKFFEQYEV TYQILKRAAEMYAKANGSVEEVENVMKFMSDTTAQWRNLSVEVRSVRSMLEEVIANWDRY SSTVAGLQAWLEDAEKMLNQPEHSKKDFFRHLPHWIQQHTAMNDAGNFLIETCDETISRD LKQQLLLLNGRWRELFMQVKQYARADELDKMRKEYVDGVAHLTAFIDGSNKKFSSPVEVS FHDVKMFVQDLENIKQKLPAMEAQYKAVTRTVQLVTKEVSQEEANEMLGTLTRLKEQLGK VKEYSSALLHECQRLLSPLEELEKQITHFYESLEKVNEIISILDPEAQPTTVLKQKAQDL VAYQENCKKDVSLIERNSQSILQCVTSTEVLQHFHQSTFQKKVTQVQITFQNMVRKAGEW RKNIEANSRLMKKFEESRAELEKVIQIANCCLKEKGNPEELLRKHSEFFNQLDQRVLNAF LKACDELTDILPEQEQHSLQEAVRKLHRQWKDLQTEAPYHLIHLKIEVQKSKFLVTVEEC KAELARQNKVLSREGNERMIKEHMLFFGDKGSYHLCEKRLQRMEELCQKLPVSDPVRGTL ESSHRILKDLKSQIDSTYMKLTEHSDTWKGYKSRFSELASWISSTERELKKIKENVNDTA KYKQCKASVGEIRKHIHKHGENHSWLKSRLAVLTSQCPELEAKETEDELFKLSGDFKRLL DLLAEIENTLGAVGDCVQYKEEVKSAIEELINNSKEVQAEAEKILDTESLLQAQQLLLHH QQRTRRLRAKRQDVQKQISQAKRLQIEGGLPSTVREDLQKLEGTLENMQQTMEKREEQLQ VTINKWEQFERDKETVVKYLNQASSVLERILNFSSLESLSSELDQTKELSKQTEAMAVQA ENLVKNSSEIQLGSKNKQSLQHQAKSIQEQVKKVEVTLEEDIKSMEMVKNKWDHFGSNFE ALSIWIAEQEKELETLETSSSPLDIQISQIKVISKEIDGKITGISNLEEEAKSFSQFVTS GEHARIKAKLTQVKRYWEELRDHAQRLEGTITGNASAQQKYEESLKQMQQSVSEFEAKLA EPLTSCSSAAATYAALQDCTDLCHTVEKLSNPLASLSAGVRKVASKEKAAQEVTALQQKY EKVLESAKEKQSLLENLLAQWQKQEKELSAFLAWLEGCEAAGRPSEQYVSADRIKLEGEL QALQDLRADIESHTSVYESLLQLNESLFPTASKQCVKTIKEKFEDLDGRWKALPQIVDKR INFLQSLVAEHGQFDELLLRFSDWIKQFLAELQATSEINTADQQLAASHNKNHSMEVESK KQELQSLKEHVEKLGSFSSPEDQQTLQGKTEDCFQIFQEASQITSQRQDALDQLRVFLEL HNAASGVLHQLRQTVEKTGNMDKAKSEFLLKELNGVIKDLNKLESDAVSLDGSLTKAQYH LKHSISGQRTSCRAMVDNLGVELEAVQNLLGTKQSEAEALGALQRSFMERKEQLLKSIED TEEKADKEGLKETTLQAFQQRLRIFNQLEEELNSHHHELQWLMDKAKQIAQKDVTLAPES DKEINRLESLWKDTKKAIQEKKEQSCILIDLMKEYQSLKSTVMKVIDSANSASVTKSIWK DHEEIRRTLAKHEAAKNDLSDKQKDLDTFTNTGKHLLAELKRVHNCDSTALKTDMNSMVD KWLDVSERLDDNIDRLSVSVSLWDDILKTGDELDGWCNKCISQLNEGINNFSNSQRMEVL LKDFQSEVKNKELKLEQLSSKISELKELTHSQEPPADLQFIESDLRQKLEHAKEISETAK ETLKDFSTQKMQLQKLIGQMTDWLTQVEETLLSCARNLDPEALNKLKETQKDLQLRQSSI DSTRETLNSLCRKYHSVELEALGGTVTLLIKKYEAVNLLCSRTQARMQDSLEKHFLYSMQ EFQEWFSGVKAAVKESSDRSGDSKAIEAKLHDLQSVLDSISEGQNKLDAACKEGESLYGC LPEPVVSHIQEQIAKSNQSFQEFLNQCLNDKKALEDCASHLGSFEDQYKKLALWMHDTEE RISTEALGENKQLVSEKKKEVQKVEKFLEELLNSRDSFDQLSQMAQTLNEEGHGAGREVR LASQHLSNYQNMVKNVKEKLRTCQLALQEHLTFEEALQSMWSWVKEVQDKLASSQSTLGS RATLERRLTQIQEILLLKGDGEVKLNMAIGKGEQALKSSNEEGQKVIQTELQTLKDVWND IISTSVNWQSCLDSVISQWNDYLERKNQLEQWLENLDHKVEQPLEPQIGLKEKFAQLDHF QAIVSEIEDHSGDLQQLIEKAVELYEKTGDDSFGDAAQEELKTQFNDISTVAKEKMRKVE DIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDASGDTPTIQKKLAKINELVESRQSGAGR LSRVEALAPAARRGTTAGGCQLLAAEMQALQADWRQWEESARRSQGGLRDLLSQMALSER EFAAQAGRLEEAVQRLGGQLAAWAQGLAPADSRSTDAEVVESWRKEKETLDALLKSEQMT DEIKTQLNDLCRFSRDLSTHSSKVSGLIKEYNSLCLQASKGCQSKEQILQQRFRTAFRDF QQWLVNARVTTAKCFDVPQNISEASASLQKIQEFLSESENGQQKLNLVASKGELLCSVLP EEKAKVIQDKSAAAKEDWKNFITTLHRKKSALENLKIQMKDFEATAEPLQEWLTTTEKIV QGSSSRLHDLPSKKREQQKLQSVLEEISCHEHQLNRLKEKAQQLWEEQAVSKSFMRRVSQ LSSQYLTLRNLTKEKVSRMDRIVAEHQQFSQSVKDLQDWVDDAVHMLDSYCHPTADKSVL DSRMLKLEGLLAVKQEKEVQMKIVLTRGEAVLQNTSLEGVPVIEGQLQNLKDSWASLLSA CIQCKSQLEGALSKWTSYQEDVNQFSRWMEKVEASMNASERQCAELREKTAALSKAKLLN EEVLSHNSLLETIEVKGKGMAEHYIAQLELQDLQERYKFLKERTKEAVTKAEGLLTLHQE YQRNLKAFEIWLEKEQEKLDCLSHLDGDAQEQEVTLRDLQELQVHCAEGQALLNAAVHAR EEVIPWGIPQIEDRALESLQQDWQVYQHRLSEARSQLNATVSKLRLMEKKFEKVNDWLTN LEEKVAIRTGRRSSRATKEMQLQQMKKWHEDITIYKDDVEEVGVLAQQILEENLTASRMG SQATQLTSRYQTLLLHVLEQVKFLEEEIRCMEESELSFSAYTNWYGATNKNFKNVITKFD VVDKTVMEKKVQKLEMLLSDMDIGHSLLKSAREKGERAIKYMEENEVDQLRKEIGDHVEQ LEELAGSIRKEHMTSEKCLQLVKEFSDKYKAQTQWVMEHQAILHAPVEPKSELYEKKAQL SKYKSIQQTVLSHESSIKSVIEKGEALCDLVNDVTLKNNIQDLQSSYQELCSKTKVYVET LEVRVKEHEDYNSDLQEGEKWLLHMSSRLASPDLMESNNLEIITQQLANHKAIMEEIAGF EDRLNNLKSKGDYLISQCSEHLQAKFKQNIQSHLQGTRDSYSAICSTAQRVYQTLEHELQ KHVNHQDTLQQCQTWLSTVQSDLKPTTWTPFSLADAVKQVKHFRALQEQANTYLDLLCSM CDLSDAAVKSTAADIQQTKQTIEQQIMHSQYLSQGWEEIKQLKAELWIYFQDADQQLQNL KRRRAELELNIAQNMVLQVKEFSQKLQTKQSALTSVSEKMNKLTQGQESPEHKEIEELSN QWLDLCLQAHSLLMQREEDLQRTRDYHDRMNVVEVFLEKLTKEWDNLARSDAESTNVHLE ALQKLAIALQERRFALEDLKDQKQKMIEHLNLDDKELVKEQFSHFEQRWTQLEDLVKRKI QVSVSTLEEFSLVHSKFQELMEWAEEQQPSVSEALKQSPPPDMAQSLLMDHLTICSELEA KQLVLKMLVKDADRVMTNLGLNERQELQKTVSDAQHHVACLSDLVGQRRKHLNKALSEKT QFLMAVFQATNQIHQHEKKVMFPEHICLLPEDVNKQIRTCKNTQANLKAYQNEVTGLWAQ GRDLMKEATNQEKSEVLGKLQELQNVYDTVLQKCNQRLLELEKNMVSRKYFKEDLDKVCH WLKQADIVTFPEVNVMNSNTELYSQLAKYQQILEQSPEYENLLLTLQRDGQEVLPSLNEV DHSYLDEKLNSLPQQFNIVTALAKEKLYKVQEAICARKEYASLIELTSKALTELEDQFIN MDKAPAAVSAKEAVSLQQAYRDLLGEAMSLAAAVDELNQKKEAFRSTGQPWQPDEMLKLA TLYHKLKRQIEQKINLLEDTIEACQEHEKMCMQFEAQLETVKKEQVKVNEETLPIEEKLK IYHSLVGSLQDSGSLLKRITEHLEALSSQVDSSAYETTNHQVQAWQEKLKSLHSAIVDMV MECENRLVQSIDFKTEICRSLDWLRWVKTELNGTLSLDLKLQNIQEEIRKVQIYQEEVQS SLRIMNALSNKEKERYMKAKELIPADLENTLAELTELDGEVQDAIHVRQATLNKAYSLCQ RYYQVMQIANDWLEDAQELLQLARNGLDVENSEENLRNHVEFFSTESQFNDHLKELQGLV SEIEPFLQATASEQLVQNVAALEGKAKGTEQEAKTQQEQLQRCASEWQEYQTSRQKVIEV MNDAEKKLSEFSVAKAASSQEAEEKLLTHKSLVSIVNSFHEKITALEEKASQLEKISNDA SKASISRSMTTVWQRWTRLRNVAQEQEKILEDAVQEWKSFNDKIQKATIAIDQLQARLPE SSVEKASKTELLELLDYHGSFLLEVDHQLSSLGLLKQHAVSMLQDVEVKPPSQKELPVMQ EIKAMQDRCHNMQHKVKKGMKMVKQELKEREEVEAEINIVKSWIQETKEYLLSPDAEVDI QLQELQSLFGEVTTHRQAVEKLAEQQQNKYLGLYTILPSELSLHLAEVGLALVTVQDQIQ TKERETQQIKTLNQEFDQKIQGIANELNTILSKLKKKTNDIAQAKLEQKILGDELDSCNI KLLELDASIQDFAEQNIPLAKQLAHRVGKLTALHQQTIRQAEYRAAKLSQAASHLEEYNE MLEFILKWIEKANILVHGSITWNSSSQLRDQFKAYQSILDESGEIHGDLEAMSERIDYLA SVYCTEGMSQQVLELGRRTEELQQVIKVQLPNLQDAAKDMKKFEIELRGLQAALEQAQAT LTSPELGHLSLKEQLSHRQHLLSEMESLKPKVQAVQDCQSALRIPEEVVTSLPMCHSALR LQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQMIESAHREIQDKPIATSNIQEL QVQISRNEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLSEGMEELDSD LLPAHPTHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQ DIAYYQALSAEQLQTEAAKIQPSTSATQEFFEPGLESSASAKLDDLQRSWETLKNVISEK QRTLYEALERQQKYQDTLQSISTKMETTEIKLNESLEPAKSPESQMAEHQALMDEISMLQ EEISELQTSLAQELVSEPLDAEGADQMALQSTLTVLAERMATIRMKASGKRQLLEEKLNE QLEEQRQEQALQRYRCEADELDHWLLSTRATLDTALLPAEEPMDMEAQLVDCQNMLVEIE QKVVALSELSVHNENLLMEGKAHTKDEAEQLAVKLRTLKGSLLELQRMLHDKQINIRQGS LQEKEESDLDFISSQSPSVQEWLAQARTTRSQQQQSTLQQQKELEQELEEQKNLLRSVAC RGGEILTQQSSVEGLSISEKPDVLSEELVLEGEKPSSEEQMKRKWESLNQEFSTKQRLLQ KALEKEQLQLYSRPNRLIPGMPLYKEETQDEDKSLVSPVLVELNQAFEDVTSEAGQVEET LHLEQKLYDGVTATSVWLDGVEEQVFVAAALLPEEETETYVCKQESLAKEIKDITEEVDK NKNLFAQILPDGSDKRVVIEDTLDCLLRRLTLLESVVNQRCHQMKGRLQQIITFKNDLKL MFTSVADNKYLVLQKLAEAADRPETEQMQVILQAEEGLKELDAGINELKKRVDKLQIDQP SVQELSKIQDKYDELLMIIGSRRSDLNQNMALKRQYERALQDLADLVETGQEKMAGDQKM IVSSKEEVQSLLEKHKEYFQGLESHMILTETLFRKMSSLALLKETQSHSEVMTRASAVLK LAHKQGVELEYILETWMHLDEDYQELTRQLESVEGNIPTVGLVEETEDRLTDRITLFQHL RSNLTEYQPKLYQVLDDGKRLLFSVSCSELEGQLNQLGERWLSNTSKVTKELHRLETILK HWTRYQSESNELTQWLQSAKERLEFWSQQSLTVPQELETVRDHLNSFLEFSKEVDAKSSQ KSSVLSTGNQLLRLKKVDTAALRAGLSNIETQWTELLTQIPAVQEKLHQLQMDKIPSRHA ITEVMSWISLMENVIQQDEENIKNVVGQKAVQGYVQKYKGFKIDLNCKQLTVDFVNQSVL QISSQDVESKRSDKTDFAEQLGAMNRRWQILQGLITEKIQLLESLQESWTEYENNVQCLK TWFETQEKKLKQQQKIGDQASVQNALKDCQELEESIRTKEKEVENVEHSGLSLVQNKKED VSSAVMNTLKEINHSWANLDHMVSQLKILLQSVLDQWSIYKVAYEELNSYLTEARYSLSR FYLLTGSLEAVKVQVDKLQSLQDELEKQENSLQKFGSVTNELLKECHPPVTETLTNTLKE VNMRWNNLLQEIAERLRASRALLQLWQRYKDCYQQCSSTVQQREEQTNELLKTATSKDIA DDEVTTWIRDCNDVLTDLKTAQESLVVLQELGEELKSQVEASAAAAIQSDHLSLNQNLST LEQALRKQQAALQAGVLDYQTFAKNLEVLENWITEAEETLKEQDPSHSSDVSAIQSRMEQ LKSQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFL LQQQTFLEKCGTWMDLLVQTEQKLAVEVSGNYQRLLEQQREHELFQAEMFSRQQILHSII SDGQHLLEQGQVDDRDEFNLNLTLLSNQWQGVIRRAQQMRGIIDSRIHQWQRYRELAEKL RKWLLEMSCQPVTELGTVPIPLQQARVLLDEVQLKEKVLLRQQGSYILTVEAGKQLLLSA DSGAEAVLQAELTEIQERWKIVSTQLEQQKKQLALLLKDWEKCEKGIGDSLEKLRSFKKK LSQPLPDHHDELHAEQIRCKELENAVEGWTDDLAHLSLLKETLSVYISADDISILSERIE LLHRQWEELCHQVSLRQQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMI EKLKKDYQEEIAVAQKNKIQLQQMGERLAKASHESKAAEIEYKLGKINDRWQHLLDLIAA RVKKLKETLVAVQQLDKNMSSLRSWLAHIESELSKPIVYETCDSEEIQRKLNEQQDLQRD IEKHSTGVASVLNLCEVLLHDCDACATEAECDSIQQATRNLDRRWRNICAMSMERRLKIE ETWRLWQKFLDDYSRFEEWLKASERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQ LELINKQYRRLARENRTDSAGSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFET ARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNNNKIEQIIVQGEQLIE KSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLTDDEHDLSDREVDLDESADL SDIRWHDKSADSVLSPHPSSNLSLPLSQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDL ETAVSRALHSEEDGGQEKDFYLRGAAGIADVEIPETLEACVTLTENALKNISGEPGALEA HIRQLDKALDTSRFQIQQTENIIRSKTPTGPELDSTYKGYMKLLGECSGSIDSVRRLGYK LKEEEEKFSGLINMNSTETQTAGVIERWELIQAQALSKELRMKQNLQQWQQFNSDLNSIW AWLGETEEELEKLQRLDLSTDIQTIELRIKKLKELQKAIDNRKAIILSINLCSSEFTQSD SEESKRLQERLSQMNVHWEHACSMIEDWRSSLQDALIQCQDFHELCHGLLLWLENIDRRK NEIVPINPSLDSEILQDHHRLLMQIRRELLESQLKVASLQDMSCQLLVNAEGKDCLEAKE KVHVIGNRLKLLLKEVTRHIKDLEKILDISSSQLELSSWSSDELDTSGSVSPVSGRSTPS RQRTPRGKCSLSQPGPSVSSPHSRSTRGGSGSSRSEAGPAWQCPSFFLRVLRAALPLQLL LLLLIGLACLVPMTEEDYSCAMANNFARSFHPMLKYMNGPPPL NT seq 26412 nt NT seq  +upstreamnt  +downstreamnt atggcttcatcccgactagcggccagatctagagacattgccaatgtcatgcagcggctt caagatgagcaagagtcagtgcagaagcggactttcacaaaatggatcaatactcatctg gctaagcgtaatcctcccatgctggtgaatgacctgtttgaagatatcaaagatggggta atgctaattgcccttttggaggttctttcagggcagaagctgccttgtgagcagggacgt cagctgaagagaattcactgggttgccaacattggcacagctcttaagtttctagaaggt agacggattaagcttgtcaacataaactcaactgatattgctgatggcagaccttctatt gtgcttggcttggtgtggaccataattttatactttcagattgaagagcttacaagtaac ctcccacagctgcagcccttgtctagcagtgcttcttctgtggaaagtgttgtcagttca gaaactgcaagtcccccaagcaaacggaaggtggtaaccaaggtccaaggaagtgccagg aaggctttgcttaaatggttacagtacacagcagcaaagcaagttggaattgaaatcaag gattttggacaaagctggaggagtggtgttgcatttcattctgttattcatgctatccgc ccagatttagtggacatggagaaagtgaggggaaggtcaaacagagaaaacctggaagaa gccttcacaattgcagaagcagaactaggaatcccaaggctccttgacccagaagatgtg gatgttgaaaagccagatgaaaaatctgtcatgacctatgtagcccagtttttgaagtac tatcctgatcctcatcatacagtgactgatgtgccagagaatgataaggaagacagactg gtgctaagagacctaaaagtgtgggcagaacaatttgaaagagacattgcccgagcacaa gtggcggaaacaagcttacaagagaaataccagtcatttaagcatttcagagtacagtat gaggtaaaaaggaagcaatttgaacttgcaacccaatcagtaaggaaagatggtaaatta tcacttgatcaagctgtggtgaagcaagcatgggagagagttacttccaggatgcttgat tggcacatacaccttgataaatcccttcctgcacctttgggtactataggtgcttggctg tacagggcagaggctgccctgagggaagaagtagctattcagcaagctcatgaggaaaca gcaaacacaatacacaggaagcttgagcaacataaggatctgctgaaaaacatagatggt cacaaaaaggcgttccatgagatccacaggaccaggtctgttaatggcgtgcctgttcca catgaccagttagaggatatggcagacaggtttaattttgttgtctcttcatctgagctc catctgttgaagatggagtttctggaactgaagtaccgtctactgtcactcttagtcttt gcagaatcaaagttaaaatcatggattatcaaatacggaaggcgagagtccgtggaactg cttcttcaaaattatatttctgttattgaaaatagcaagttctttgagcagtatgaagtt acctaccagatcttgaaacgagcagctgaaatgtatgccaaagcaaatggctcagtggaa gaagttgagaatgtaatgaaattcatgagtgataccacagctcagtggaggaacctctca gtagaggtgagaagtgtaagaagcatgctggaagaagttattgctaattgggacagatac agcagcactgtggcaggtctacaagcttggcttgaagatgctgaaaaaatgttgaatcag cctgaacattccaaaaaggatttcttccggcacttacctcattggatccagcagcacaca gccatgaatgatgctggtaattttctgattgaaacatgtgatgagaccatttccagagat cttaaacagcagcttttgttgctaaatggaagatggagagaactgtttatgcaagttaag cagtatgctcgagcagatgaactggacaaaatgaggaaggagtatgtggatggtgtggcc catttgacagcttttattgatgggagcaataagaaattttcaagccctgtagaagtgtcc tttcatgatgtcaaaatgtttgtgcaagatttagaaaatattaagcagaaattacctgca atggaagctcagtacaaagcagttacgaggacggtgcaacttgttacaaaggaagtttcc caagaggaagcaaatgaaatgctgggaactttgacacggctcaaagagcagctgggcaag gttaaggagtattccagtgccctgctgcatgaatgccaacgtctgctgtctccactggaa gaactggagaaacaaatcacacatttctatgaatctcttgaaaaagtaaatgaaatcatt tctatcctggatcctgaagcacagccaacaactgttcttaaacaaaaagcccaagatttg gtagcttatcaagaaaactgcaagaaagatgtgtccctaattgagagaaatagtcagagt atccttcagtgtgtgacttcaactgaagtgttacagcatttccatcagtcaacatttcag aagaaagttacacaagttcagattacttttcagaatatggtcaggaaagctggagagtgg agaaaaaacatagaagcaaatagtcgcttgatgaagaaattcgaggagtctagagcagaa ctggagaaagtaatacagattgccaattgttgcttaaaagaaaaaggaaatcctgaagaa cttctcaggaaacatagtgaattttttaaccagttggatcagagagtcctaaatgccttt ctgaaagcatgtgatgaacttactgatatcctcccagaacaagagcaacacagcctgcag gaagctgtaaggaaactccataggcagtggaaggatcttcaaacagaagccccatatcat ttgatccacttgaaaattgaagtacagaaaagcaagttcctggtgacagtggaggagtgc aaagctgaactagctcgacagaacaaggtgttatcaagagaaggcaatgaaagaatgatc aaggaacacatgttgttctttggtgataagggatcttaccacctgtgtgagaaaaggcta caacggatggaagaactctgccaaaaactgccagtttctgatccagtgaggggtacattg gaaagcagccatcgaatcctgaaggatctgaaatcccagatagacagcacatacatgaag ctaacagagcactcggacacctggaagggctataagagcaggttttctgaattggcaagt tggatttcatcaacagaaagagagctaaagaagataaaggaaaatgttaatgatactgcc aaatacaaacagtgtaaagcatctgtgggggaaattaggaagcatattcacaagcatgga gaaaatcacagctggctgaaatctagacttgctgttttgacttcacaatgtcctgaattg gaggccaaggagacagaggatgagctttttaaactttccggtgactttaagagacttcta gatttgctggctgagattgaaaataccttaggtgctgttggagactgtgtccagtacaaa gaagaagttaaaagtgcaattgaagagttaatcaacaactctaaagaagtccaagcagag gctgaaaagatcctggatacagaaagtttattacaagctcagcaactactgcttcatcat cagcaaaggacaaggagactccgtgcaaaaaggcaagatgtgcaaaagcagatttcccaa gccaagcggttgcagattgaaggtggactgcccagcacagtacgagaggatttacaaaaa ttagagggaacattggagaacatgcagcagactatggaaaaacgggaagagcaactgcag gtcacaataaataaatgggagcagtttgaaagagacaaagaaacagtagtaaaatatctc aatcaagcaagctctgtacttgaacgcatcttaaactttagcagtttggagagcctctcc tcagaactggatcagacaaaggaactttctaaacaaactgaagcaatggcagtacaggct gagaatttggtgaagaattcctctgagatacagcttggttcaaagaacaagcagtccctt cagcatcaggcaaaatcaatccaagaacaagtgaaaaaagtggaagttactcttgaagaa gatattaaaagcatggaaatggtgaaaaacaagtgggatcattttggcagtaattttgaa gctctgtccatatggatagctgaacaagaaaaagaactggaaactttggaaacatcatca tctcctttggacatacagatcagccaaatcaaggttattagtaaagagatagatggtaaa ataactggaatctcaaatctagaagaggaagccaagtctttttcccagtttgtcacctct ggagaacatgcacgtattaaagccaaactgactcaggtcaaaaggtattgggaagaacta 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gccctgaggattcctgaggaggtggtcaccagcctgcccatgtgccacagcgccctgcgg ctccaggaggaggccagccgcctgcagcacacggccatccagcagtgcaacatcatgcag gaagcagtggttcagtatgagcaatatgagcaagaaatgaaacatttgcagcagatgata gagagtgcccatcgtgagatccaagacaagccaatagcaaccagcaacatccaggaactc caggtccagatttcacgtaatgaggagctggctcagaagatcaaaggataccaggagcaa attgcttctttgaattccaagtgcaagatgctgacaatgaaagcaaaacatgccaccatg ctgctgacagtgacagaagtggaggggctgtccgagggaatggaggagctggattcagac ctgcttccagcacaccccactcatccctcggtggtaatgatgactgcaggtcgctgtcac acgctgctctctcctgtcactgaggagtctggggaggagggaaccaacagtgagatatct tctccacctgcctgtcgctctccctcacctgtggctaatacagatgcttctgttaaccag gacattgcttattaccaagccttatctgctgaacagttgcagacagaagctgctaaaatt cagcccagcacctcagccacccaggagttttttgaaccaggcttagaatcatctgctagt gccaaattggatgatttgcagcgttcttgggagacactgaaaaatgtgatcagtgaaaag cagcgcacactctatgaagctcttgagcgtcaacagaagtatcaggatacactccagtct atatccacaaaaatggaaaccactgaaatcaaactaaatgagagtttggaaccagccaaa agcccagagagccagatggctgaacatcaggctttgatggatgagatttcaatgttgcaa gaagaaatcagtgagcttcagacatcattggcccaggagcttgtttcagaaccactggat gcagaaggtgctgatcagatggcattgcagtccaccctcacagtcttggcagaacgaatg gccacaattcgaatgaaggcatcaggaaaacgacagctattagaggaaaaactgaatgag cagctcgaagagcagcggcaagagcaggctcttcagaggtaccgctgtgaggctgatgag cttgaccactggctactcagcacccgagcaacgctggacaccgctctgcttcctgccgaa gagcctatggacatggaagcacagctggtagactgtcagaatatgttggttgaaatagag cagaaggtggtagccttgtcagagttgtctgtgcacaacgagaacttgcttatggaaggg aaggctcacaccaaggacgaggcagagcaactggctgtgaagctcaggacactgaagggc agccttctggagcttcagagaatgctccacgacaaacagatcaacattcggcagggatct ttacaagaaaaggaggagagtgatctggacttcatttcctcacaaagccccagtgttcaa gaatggctggcacaagcaagaactactcgctcacagcagcagcagagtaccctgcagcaa cagaaagagctagaacaagaattggaagagcagaagaatctgcttcgatcagtagcgtgc cgtggaggagaaatcctaacgcagcaaagctctgttgaaggcctgtccataagtgagaag cctgatgtactctctgaggaattagtcttagagggtgagaagccatcatctgaagaacag atgaagaggaaatgggaaagtctaaaccaggaattcagtaccaagcagagactgctccag aaagctttggaaaaagaacagctgcagctttatagcagaccaaacaggctaatacctgga atgcctttatataaggaggagacacaggatgaagataaatctttagtgtcaccagtattg gttgaattgaatcaggcctttgaagatgtcacatctgaggcagggcaggtggaagagacc ctgcatcttgaacagaagctgtatgatggtgtcactgccacatctgtgtggctggatggt gtggaagagcaagtctttgttgctgcagctctgttgccagaggaagaaacagaaacctat gtctgcaagcaagagtctcttgccaaagaaatcaaagacattacagaagaagtggataag aacaagaatttgtttgctcagatacttcctgatggtagtgataagagggttgttatagaa gacactttggattgtctcctgagaagactgaccttactggagtcagtggtaaaccagaga tgccaccagatgaagggacggctccagcaaatcatcacattcaagaatgatctgaagctc atgtttacatcggtggccgataacaagtacttagttctacagaaattagcagaggcagct gacagaccagaaacagaacaaatgcaggtcatactgcaggcagaagaaggtttaaaggaa ctagatgctggaatcaatgaattaaagaagcgtgtagacaaactacaaattgaccaaccc tctgtacaagagttgtctaaaatccaggataagtatgatgagctactgatgatcattgga tcgaggcggagtgatctgaatcagaatatggctctgaagaggcagtatgagcgggctttg caggacctggctgacctggtagaaacaggccaagaaaaaatggctggtgaccagaaaatg attgtttcttccaaggaagaggttcagtcactgcttgaaaaacataaggagtattttcaa gggctggagtctcacatgatcctgacagaaacactttttagaaagatgagtagccttgcc ctcttgaaggaaactcagtcacattcagaggttatgacacgagcttcagctgtattaaag ctggctcataaacaaggtgtggagctggaatacattctagagacctggatgcatctggac gaagattaccaggagctcaccagacagctggagtctgttgaaggaaacatccccactgtt ggtttggtagaagagacggaggacaggcttacagaccggattacactttttcagcatctg aggtctaacctgactgaataccagcctaaattataccaagtgctggatgatgggaagagg ctccttttttctgtcagctgctcagaactcgaaggtcaactgaaccaactaggggaacgc tggttaagtaacaccagcaaagtcaccaaggagcttcacaggctggagacaatactgaag cactggacgaggtatcagagtgaatcaaatgaattgacacagtggttgcaatctgcaaag gagcgacttgagttttggagccagcagtctttgactgttcctcaggaactagaaactgtc cgagatcacctcaactcatttttggagttttcaaaagaagtggatgccaaatcatcacag aaatcttctgtcctgagtactgggaaccagctccttaggcttaagaaagtagatacagct gcattgcgtgcaggattgtccaacattgaaacccagtggacagagcttctcacacaaatc ccagcagtacaagagaagttgcaccagctccaaatggacaagattccttctcgccatgcc atcactgaagttatgagctggatttcactgatggaaaacgtaattcagcaggatgaagaa aatataaaaaatgtagtaggacagaaagcagttcaaggttatgtccagaagtacaagggt ttcaagatagatttaaattgcaaacagttgactgtcgactttgtgaaccagtcagtgcta caaatcagcagccaggatgttgaaagcaagcgcagtgacaaaactgattttgcagaacag cttggagcaatgaacagacgttggcagatcctacaaggcctgataacagaaaagatccag ctcttggaaagtctacaggaatcctggacagaatatgaaaataatgtgcagtgcctaaaa acttggtttgaaacccaagagaagaagctgaaacagcaacaaaaaattggagaccaggct tcagtgcagaatgctttgaaagactgtcaggaattagaagaatcaataagaacaaaggaa aaagaagtagaaaacgtagaacacagcggtctgtctttggtacagaacaagaaagaggac gtctcctctgctgttatgaatacactgaaagaaattaaccattcctgggccaatttggat cacatggttagtcaactgaagatactgttgcaatccgttcttgatcagtggagcatttac aaagtggcttatgaagaactgaacagttacctgacagaagccagatattctttgtcccgt ttttatcttcttactggttctctggaagctgtgaaagtccaagttgataaacttcagagc ctacaagatgaattggaaaaacaagagaacagcttacagaaatttggttctgtgaccaat gaattgttgaaagaatgtcacccaccagtgactgaaacacttaccaacactttgaaagaa gtgaatatgaggtggaacaacctcctgcaggagattgcggagcggctgcgtgccagcagg gccctgctccagctgtggcagaggtacaaggactgctaccagcagtgctcctccacggtc cagcagcgagaggaacagaccaacgagctcctgaagactgcaaccagcaaagacatcgct gatgatgaagttaccacttggattcgggactgcaatgatgtactcacagatctgaaaaca gcacaggagtctctggttgttcttcaagaactgggggaggagctaaaaagccaggtggag gcttcagcagcagcagccatacagtcggatcatctgtctctgaaccagaatctgtcaacc ctagagcaggctctccgcaagcaacaggctgcactgcaggctggagtcctggactatcag acctttgccaaaaacctggaagtacttgagaactggataacagaagcagaagaaacattg aaagaacaggatcccagtcactcatctgatgtctcagcaatacagagtagaatggagcaa ctcaagagtcagatgctgaagttcagcagcatggcccctgatttggaccgtcttaatgag ctgggttacaggcttcctctgaatgacaaggaaatcaaaaggatgcagaacctgaacaga cattggtctctgatctcatctcagactacagagagattcagtaagttgcagtctttcttg ctgcaacagcagaccttcttggagaaatgtgggacttggatggatttattagttcagact gagcagaagttggcagtagaggtttcaggaaactaccaaaggcttttagagcaacagagg gaacatgagctgttccaggcagagatgttcagccgccagcagattttgcattcaattatc tctgatggacagcacctcctagaacaaggacaggtggatgacagggatgaatttaacctg aatctgactctgctgagtaatcagtggcaaggggtaattcgccgagcgcagcagatgagg gggatcattgacagccggattcaccagtggcagcgctaccgggagctggcggagaagctg cgcaagtggctgctggagatgtcctgtcagccagtaactgagctgggcactgttcccatc ccattgcagcaagcaagagtgctgctggatgaagtgcagcttaaagagaaagttctcttg aggcagcaagggagttacatcctcactgtggaggctgggaagcagctgctgctctctgct gacagtggagctgaggcagtcctgcaggcagagctcactgaaatccaggagcgctggaag atagttagcactcagctggagcaacaaaagaaacagcttgctcttctgctaaaagactgg gaaaaatgtgaaaagggcataggagactccctggagaagctaagatcattcaaaaaaaag ctttctcagccattgccagatcaccatgacgagttgcatgcagagcagattcgttgcaag gagttagagaatgctgttgaaggctggacagatgaccttgcacacctctccctgctgaag gagaccctgtctgtatatatcagcgcagatgatatctcaatcctgagtgagcgaatagag ctcctgcacaggcagtgggaggagctgtgccaccaggtctccttgcgtcaacaacaagtt agtgagagactgaatgagtgggctgtcttcagtgagaagaacaaggagctctgtgaatgg ctgacgcaaatggaaagcaaggtgtctcaaaatggtgacatcctcatagaagaaatgatt gagaaacttaaaaaggattatcaagaggaaattgctgttgcccagaagaacaaaatccag cttcagcaaatgggagagagacttgctaaagccagccatgagagtaaggcagcagagatt gagtacaaacttggcaagatcaatgacagatggcaacatcttctagatcttattgcagcc agggtaaagaagttgaaggaaacccttgttgcagtgcagcagctggataaaaacatgagt agtctgagatcttggcttgcccacattgagtcagagctgtccaaacctattgtctatgaa acttgtgactctgaggagatacaaaggaagctaaatgaacagcaggacctccagagggac atagagaaacacagcactggcgtggcatctgttctcaatctgtgtgaagtacttcttcat gactgtgatgcttgtgccacagaagcagagtgtgactctatccagcaggctacgcgcaat ctggacagaaggtggagaaatatttgtgcaatgtcaatggaaaggcgacttaaaattgaa gagacctggcggctatggcaaaaatttttggatgactactctagatttgaagagtggcta aaagcctctgagaggacagctgctttcccaagctcctctggtgtactttacactgttgct aaggaagaactgaagaaatttgaggctttccagagacaagtgcatgaaagcctgactcag ctggagctgatcaataagcagtatcggcgcctggcacgggagaaccgcacggattctgct ggcagcctcaagcagatggttcatgaggggaaccagagatgggacaatttacaaaagaga gttacctccatcctgcgcaggctaaagcattttattggccagcgggaggagtttgaaaca gcacgtgacagcatcctggtatggctaacagagatggacctgcagctgaccaacatcgag cacttctcagagtgtgatgtccaagcaaagataaagcaacttaaggctttccagcaagaa atttccctgaacaacaacaaaattgagcagataattgtgcaaggtgagcagctcattgag aaaagtgagcccctggatgcagctgtgattgaagaagaactagatgagctgcgtcgttac tgccaagaggtctttgggcgagtggagcgctatcacaagaaacttatccgccttcctcta acagatgacgagcacgacctctctgacagagaggtggatctggatgaatcagcagatctc tctgacatacgctggcatgacaaatctgcggacagcgttctctccccgcacccctcttcc aacctttcgctgcctctttcccagccgctgaggagcgagcgatcggggcgagacacccct gcgagcgtggactccatccccctggagtgggatcatgactacgaccttagcagggacctg gagacagccgtttcacgggcactgcactcagaagaagacggagggcaagaaaaagatttc tacctgagaggagcagctggcatagcagatgtagagatccctgaaactcttgaggcctgt gtaacactcacagaaaacgccctcaaaaatatctctggtgaaccaggtgccctggaagca catatccgccagctggacaaggccttggacaccagtcgcttccagatacaacaaacagaa aacatcatccgtagcaagacacctacaggaccagaactggattccacttacaaaggatat atgaaactgctaggtgaatgcagtggaagcatagactcagtaagaaggcttggatataaa ctgaaggaggaagaagaaaaattttcaggactcattaacatgaacagtactgaaacacaa acagctggtgtaattgaaagatgggaattaatccaggctcaagctctaagcaaggagctg aggatgaagcagaaccttcagcaatggcagcagttcaactccgaccttaatagcatctgg gcttggttgggagaaactgaagaggaactggagaagctccagcgccttgatctcagcact gacatacaaactattgagctcagaattaaaaaactaaaagagctgcagaaagcaattgat aaccgcaaagcaatcatcctgtccatcaatctgtgcagctcagagttcactcagtctgac agcgaggagagcaagaggcttcaggagcgcctgtctcagatgaacgtgcactgggagcac gcgtgcagcatgatcgaagactggcgcagctcgttgcaggatgcattaatacagtgccag gatttccatgaactatgccatggtttgctgctttggttggagaatattgacagaaggaaa aatgagattgtgcccatcaatccaagcctggactcagaaatactgcaggatcatcacaga cttcttatgcaaatcagacgtgaactgctggagtctcagttgaaggtggcatcactgcaa gatatgtcttgccagttgctagtcaatgctgaaggcaaggattgtcttgaagccaaagaa aaggtacatgtcattggaaacagactgaagctcctcttgaaagaggttacacgtcatatt aaagacctagagaaaattctagacatttcaagtagtcaactggaattgtcctcatggtct tctgatgaattagacacatcaggctcggtgagtcctgtatctggaagaagcactccaagc agacagagaacgccacggggcaaatgtagtctctcacagcctggaccctctgtcagcagt ccacatagcaggtccacaagaggtggctcaggttcctcccgttctgaggctgggccagca tggcagtgcccatccttcttcctcagagtcctcagagccgctctgccacttcagctcctg ctgctgctcctgatcgggctggcgtgcctggtgcccatgaccgaggaggattacagctgt gctatggcaaacaactttgcccgctctttccaccccatgctaaaatacatgaatggtcct cctccattgtga

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