Streptomyces auratus: SU9_023735
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Entry
SU9_023735 CDS
T07630
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sauh
Streptomyces auratus
Pathway
sauh00020
Citrate cycle (TCA cycle)
sauh00630
Glyoxylate and dicarboxylate metabolism
sauh00785
Lipoic acid metabolism
sauh01100
Metabolic pathways
sauh01110
Biosynthesis of secondary metabolites
sauh01120
Microbial metabolism in diverse environments
sauh01200
Carbon metabolism
sauh01210
2-Oxocarboxylic acid metabolism
Module
sauh_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sauh_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sauh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SU9_023735
00630 Glyoxylate and dicarboxylate metabolism
SU9_023735
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SU9_023735
Enzymes [BR:
sauh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SU9_023735
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SU9_023735
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SU9_023735
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SU9_023735
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QTZ94084
UniProt:
J1S9U2
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All DBs
Position
complement(5418702..5422514)
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AA seq
1270 aa
AA seq
DB search
MSLQSPNSSSISTDHEGQGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GATTAPSQPAEGAAPAAAAPAQSSPAAPPAAAPKPSGTGTADAAPAPAPAAPAKPAASAP
APAQPAPAKSAPAKAAAKPAAAPAAEATGGPEFVTLRGPSAAVAKNMNASLELPTATSVR
AIPVKLLFDNRIVINNHLKRARGGKVSFTHLIGYAMVQALKAMPSMNYSFALKDGKPTLV
KPEHVNLGLAIDLVKPNGERQLVVAAIKKAETLTFFEFWQAYEDIVRRARDNKLTMDDFT
GVTASLTNPGGIGTVHSVPRLMPGQSMIMGVGSMDYPAEFQGTSQDALNKLGVSKVMTLT
STYDHRVIQGAASGEFLRIMNQLLLGENDFFDDIFKSLRIPYEPVRWLKDIDASHDDDVT
KAARVFELIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGGFSGKS
MMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRQWIQDRVERSHKSPEREEQLRILRRLNS
AEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDECVIGMAHRGRLNVLAN
IVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLTANPSHLEAV
DPVVEGVSRAKQDIINKGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVH
IVINNQVGFTAAPESARSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNK
DVVIDLICYRRRGHNESDNPGFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQAL
QDFQGQLEKVFTEVRDATTTPAAPEVPQPKAEFPVYVDTAISQEVVKRIAESQVNIPERV
TVHPRLLPQLQRRAAQVEDNTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHAV
LVDRETGEDYTPLLYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPEALVMWEAQFGDF
VNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVA
MPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFMTGGFRPVIGDATVK
AEDVRKVIFCSGKVYYDLEAEREKRGATDTAIVRIERLYPLPGKELQAEIAKFPNAAKYL
WTQEEPANQGAWPFLGLNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQ
AQLVAEAFDA
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacagctcgagcatctcgaccgaccacgaggggcagggaaag
aaccctgccgccgcgttcggtcccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggcgccaccacggcgccgagccagccggcggagggcgctgcccccgctgcggccgccccg
gcgcagtcgtccccggcagcgccccccgccgccgcgccgaagccgtccggcaccggaacg
gccgacgccgcgccggccccggctccggccgccccggcgaagccggccgcgagcgctccg
gcgcccgcccagccggccccggccaagagcgccccggccaaggccgccgcgaagccggcg
gccgcgcccgccgccgaggccacgggcggtcccgagttcgtcacgctgcgcggcccctcg
gccgctgttgcgaagaacatgaacgcctccctggagctgccgacggccacgtccgtccgc
gcgatcccggtgaagctgctcttcgacaaccgcatcgtgatcaacaaccacctcaagcgc
gcccggggcgggaaggtctccttcacccacctcatcgggtacgcgatggtgcaggccctc
aaggccatgccgtcgatgaactactccttcgcgctgaaggacggcaagccgacgctggtc
aagcccgagcacgtcaacctcggtctggccatcgacctggtgaagccgaacggtgagcgc
cagctcgtcgtcgccgccatcaagaaggccgagacgctgaccttcttcgagttctggcag
gcctacgaggacatcgtccgccgggcccgcgacaacaagctgacgatggacgacttcacc
ggggtcaccgcgtcgctgacgaacccgggcggcatcggcacggtccactccgtgccgcgg
ctgatgcccggccagtccatgatcatgggcgtcggctcgatggactaccccgcggagttc
cagggcacctcccaggacgccctgaacaagctcggtgtctccaaggtcatgacgctgacc
agcacctacgaccaccgcgtgatccagggcgccgcctccggcgagttcctgcggatcatg
aaccagctgctgctcggcgagaacgacttcttcgacgacatcttcaagtcgctgcggatc
ccctacgagccggtccgctggctcaaggacatcgacgcgtcccatgacgacgacgtcacc
aaggccgcccgggtcttcgagctgatccactcctaccgggtccgcggccacgtcatggcc
gacaccgacccgctggagtaccaccagcgcaagcaccccgacctcgacatcaccgagcac
ggtctcaccctgtgggacctggagcgcgagttcgcggtcggcggcttctccggcaagtcc
atgatgaagctgcgcgacatcctgggcgtgctgcgcgactcgtactgccgcaccaccggc
atcgagttcatgcacatccaggaccccaagcagcgccagtggatccaggaccgggtcgag
cgctcgcacaagtcgcccgagcgcgaggagcagctgcgcatcctgcgccggctgaactcc
gccgaggcgttcgagacgttcctgcagaccaagtacgtcggccagaagcgcttctcgctg
gagggcggcgagtccgtcatcccgctgctggacgcggtcatcgactccgcggccgagtcg
cggctggacgagtgcgtcatcgggatggcccaccgcggccgcctcaacgtcctcgccaac
atcgtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaag
tcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggc
ctggacggcgagcagatcaaggtctcgctgaccgccaacccctcccacctggaggccgtc
gacccggtcgtcgagggtgtctcgcgcgccaagcaggacatcatcaacaagggcggcacg
gacttcaccgtcctgccgatccagctgcacggtgacgcggcgttcgccggccagggtgtg
gtcgccgagacgctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtgcac
atcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcggcccgctcctccatg
tacgccaccgacgtggcccgcatgatcgaggcgccgatcttccacgtcaacggtgacgac
cccgaggccgtcgtccgtgtggcccgtctggccttcgagttccgccaggcgttcaacaag
gacgtggtcatcgacctgatctgctaccgccgccgcggtcacaacgagtccgacaacccg
ggcttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctc
tacaccgagtccctcatcggtcgcggcgacatcacgctggaggaggccgagcaggcgctg
caggacttccagggccagctggagaaggtcttcaccgaggtccgcgacgccacgacgacg
ccggccgcccccgaggtgccgcagccgaaggccgagttcccggtctacgtcgacaccgcg
atctcccaggaggtcgtcaagcggatcgccgagtcgcaggtcaacatccccgagcgggtc
accgtccacccgcgtctgctgccccagctgcagcgccgcgcggcccaggtcgaggacaac
accatcgactggggcatgggcgagaccctcgccatcggctcgctgctgatggagggcacc
ccggtccggctcgccggccaggactcccgccgcggcaccttcggccagcgccacgcggtg
ctggtggaccgggagaccggcgaggactacaccccgctgctctacctctccgaggaccag
gcccgcttcaacgtctacgactcgctgctgagcgagtacgcggcgatgggcttcgagtac
ggctactccctggcccgcccggaggcgctggtcatgtgggaggcgcagttcggtgacttc
gtcaacggcgcccagacggtcgtcgacgagttcatctcctcggcggagcagaagtggggc
cagacgtccggcgtcaccctgctgctcccgcacggctacgagggccagggcccggaccac
tcctcggcccggatcgagcgcttcctccagctgtgcgcgcagaacaacatgacggtcgcc
atgccgaccctgccgtcgaactacttccacctgctgcgctggcaggtccacaacccgcac
cacaagccgctggtcgtcttcaccccgaagtcgatgctgcgtctgaaggccgcggcgtcg
aagacggaagagttcatgacgggcggcttccgccccgtcatcggcgacgccacggtcaag
gccgaggatgtccgcaaggtcatcttctgctccggcaaggtctactacgacctggaggcc
gagcgggagaagcgcggcgcgaccgacacggcgatcgtccgtatcgagcggctctacccg
cttcccggcaaggagctccaggcggagatcgccaagttcccgaacgccgcgaagtacctg
tggacccaggaagagccggcgaaccagggtgcgtggccgttcctcggcctcaacctgatc
gaccacctcgacctggccgtcggcgccgacgtgccgcacggcgagcggctgcgccggatc
tcccggccgcactcctcgtcgccggccgtcggctccgccaagcgccaccaggcggagcag
gcacagctggtcgcggaggccttcgacgcctga
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