KEGG   Shigella boydii Sb227 (serotype 4): SBO_0037
Entry
SBO_0037          CDS       T00301                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase type I
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
sbo  Shigella boydii Sb227 (serotype 4)
Pathway
sbo00670  One carbon pool by folate
sbo00790  Folate biosynthesis
sbo01100  Metabolic pathways
sbo01240  Biosynthesis of cofactors
sbo04981  Folate transport and metabolism
Module
sbo_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:sbo00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    SBO_0037 (folA)
   00670 One carbon pool by folate
    SBO_0037 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    SBO_0037 (folA)
Enzymes [BR:sbo01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     SBO_0037 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ABB64773
ShiBASE_China: SBO0037
UniProt: Q326I5
LinkDB
Position
38885..39364
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg
attatgggccgccatacctgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gagcagttcctgccaaaagcgcagaaactgtatctgacgcatatcgacgcagaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgatgctgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

KEGG   Shigella boydii Sb227 (serotype 4): SBO_1530
Entry
SBO_1530          CDS       T00301                                 
Symbol
ydgB
Name
(GenBank) putative oxidoreductase
  KO
K13938  dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3]
Organism
sbo  Shigella boydii Sb227 (serotype 4)
Pathway
sbo00670  One carbon pool by folate
sbo00790  Folate biosynthesis
sbo01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:sbo00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    SBO_1530 (ydgB)
   00670 One carbon pool by folate
    SBO_1530 (ydgB)
Enzymes [BR:sbo01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     SBO_1530 (ydgB)
    1.5.1.50  dihydromonapterin reductase
     SBO_1530 (ydgB)
SSDB
Motif
Pfam: adh_short_C2 adh_short KR SDR
Other DBs
NCBI-ProteinID: ABB66146
ShiBASE_China: SBO1530
UniProt: Q320W2
LinkDB
Position
complement(1510504..1511226)
AA seq 240 aa
MGKAQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAIDGLIKAGAQCIQADFS
TNDGVMAFADEVLKSTHGLRAILHNASAWMAEKLGAPLADVLACMMQIHVNTPYLLNHAL
ERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALDNMTRSFARKLAPEVKVNSIA
PSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVDYLLTSCFVTGRSFPLDGGRHLR
NT seq 723 nt   +upstreamnt  +downstreamnt
atgggtaaagcccagcccttgccaatattaattactggcggaggtcgtcgcatcggcctc
gccctcgcctggcatttcattaatcaaaagcaaccggtgattgtcagctatcggacgcac
tatccagccattgatggactgattaaggcaggtgcgcagtgtattcaggctgatttttcg
accaacgacggtgtgatggcgtttgccgatgaagtactaaaaagcacccatggtctgcgt
gctattttgcataacgccagtgcgtggatggcggaaaaactgggtgcgccactggccgac
gtactggcttgcatgatgcagatccacgttaataccccatacctgctcaaccatgcgctg
gaaagattactgcgtgggcacggacacgccgccagcgatatcattcactttaccgattat
gtggtggagcgcggtagcgacaagcatattgcgtatgctgcaagcaaagcggcactggat
aatatgacccgctcgtttgcccgcaagctggcaccggaagtgaaagtgaattctattgct
ccatcgctgatcctgtttaatgaacatgatgatgccgaatatcgacaacaggcgctgaat
aaatcactgatgaaaaccgcgcctggcgagaaagaagtgatcgacctggtcgattactta
cttaccagttgctttgtcaccggacgcagtttcccacttgatggcggtcgtcatctgcgt
taa

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