KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101035868
Entry
101035868         CDS       T04350                                 
Symbol
IRS1
Name
(RefSeq) insulin receptor substrate 1
  KO
K16172  insulin receptor substrate 1
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq04022  cGMP-PKG signaling pathway
sbq04068  FoxO signaling pathway
sbq04081  Hormone signaling
sbq04140  Autophagy - animal
sbq04150  mTOR signaling pathway
sbq04151  PI3K-Akt signaling pathway
sbq04152  AMPK signaling pathway
sbq04211  Longevity regulating pathway
sbq04213  Longevity regulating pathway - multiple species
sbq04722  Neurotrophin signaling pathway
sbq04910  Insulin signaling pathway
sbq04920  Adipocytokine signaling pathway
sbq04923  Regulation of lipolysis in adipocytes
sbq04930  Type II diabetes mellitus
sbq04931  Insulin resistance
sbq04932  Non-alcoholic fatty liver disease
sbq04935  Growth hormone synthesis, secretion and action
sbq04960  Aldosterone-regulated sodium reabsorption
sbq05010  Alzheimer disease
sbq05206  MicroRNAs in cancer
sbq05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:sbq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    101035868 (IRS1)
   04022 cGMP-PKG signaling pathway
    101035868 (IRS1)
   04151 PI3K-Akt signaling pathway
    101035868 (IRS1)
   04152 AMPK signaling pathway
    101035868 (IRS1)
   04150 mTOR signaling pathway
    101035868 (IRS1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    101035868 (IRS1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101035868 (IRS1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    101035868 (IRS1)
   04923 Regulation of lipolysis in adipocytes
    101035868 (IRS1)
   04920 Adipocytokine signaling pathway
    101035868 (IRS1)
   04935 Growth hormone synthesis, secretion and action
    101035868 (IRS1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101035868 (IRS1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101035868 (IRS1)
  09149 Aging
   04211 Longevity regulating pathway
    101035868 (IRS1)
   04213 Longevity regulating pathway - multiple species
    101035868 (IRS1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    101035868 (IRS1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101035868 (IRS1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    101035868 (IRS1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101035868 (IRS1)
   04932 Non-alcoholic fatty liver disease
    101035868 (IRS1)
   04931 Insulin resistance
    101035868 (IRS1)
SSDB
Motif
Pfam: IRS PH PH_11
Other DBs
NCBI-GeneID: 101035868
NCBI-ProteinID: XP_003925513
LinkDB
Position
Unknown
AA seq 1244 aa
MASPPESEGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADNEAEQDSWYQALLQLHNRAKGH
HDGTAALGAGGGGSSCSGSSGVGEAGEDLSYGDGPPGPTFKEVWQVILKPKGLGQTKNLI
GIYRLCLTSKTISFVKLNSEVAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV
DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNLPPSQVGLT
RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR
GSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP
SDGGFVSSDEYGSSPCDFRSSFRSVTPDSVGHTPPARGEEELSNYICMGGKGPSTLTAPN
GHYILSRGGNGHRYTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPSISHQKTP
SQSSVASIEEYTEMMPVYPPGGGSGGRLPGHRHSAFVPTHSYPEEGLEMHLLERRGGHHR
PESSTLHSDDGYMPMSPGVAPVPSSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN
GYMMMSPSSSYSPDIGGGPGSSSSRAVPSGSSYGKLWTNGVGGHHAHVLPHPKPPVESSS
GKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQLPGELEE
GARHQHLRLSASSGRLLYAATVEDSSSSTSSDSLGGGYCGARMEPSLPHSHHQVLQPHLP
RKVDSAAQTNSRLARPTRLSLGDPKASTLPRAGEQQQQQQQQQPLLHPPEPKSPGEYVNI
EFGSDQPGYLSGPVASHSSPSVRCPSQLQPAPREEETGTEEYMKMDLRPGRRAAWQESTG
VEVGRVGPAPSGAASICRPTRAVPSSRGDYMTMQMGCPRQSYVDTSPVAPVSYADMRTGI
AAEEVSLPRATMAAASSASAASASPAGPQGAAELAAQSSLLGEPQGPGGMSAFTPVNLSP
NRNQSAKVIRADAQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAGGGSGGSSSSKDVKR
HSSASFENVWLRPGELGGAPKEPAQLCGAAGDLENGLNYIDLDLVKDIKQCPQERTPQPQ
PPPPPSPPSHQPLGSGENSSTPRSSEDLSTYASISFQKQPEDRQ
NT seq 3735 nt   +upstreamnt  +downstreamnt
atggcgagccctccggagagcgagggcttctcggacgtgcgcaaggtgggctacctgcgc
aaacccaagagcatgcacaaacgcttcttcgtactgcgcgcggccagcgaggctgggggc
ccggcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctcgatcccccttgagagctgcttcaacatcaacaagcgtgctgactccaagaac
aagcacctggtggctctctacacccgggacgagcactttgccatcgcggcggacaacgag
gccgaacaagacagctggtaccaggctctcctgcagctgcacaaccgcgccaagggccac
cacgatggaactgcggccctcggggcgggaggcggcgggagcagctgcagcggcagctcg
ggagttggtgaggctggggaggacctgagctacggggacgggcccccaggacccacattc
aaagaggtctggcaggtgatcctgaagcccaagggcctgggtcagacaaagaacctgatt
ggtatctaccgcctctgcctgacaagcaagaccatcagcttcgtgaagctgaactcggag
gtagcggctgtggtgctgcagctgatgaacatcaggcgctgcggccactcggagaacttc
ttctttatcgaggtgggtcgttctgccgtgacggggcccggggaattctggatgcaggtg
gatgactccgtggtggcccagaacatgcacgaaaccatcctggaggccatgcgggccatg
agcgatgagttccgtcctcgcagcaagagccagtcctcgtccaattgctctaaccccatc
agcgtccccctgcgccggcaccatctcaacaacctcccgcccagccaggtagggctgacc
cgccgatcacgcaccgagagcatcaccgccacctccccggccagcatggtgggtgggaag
ccaggctccttccgtgtccgcgcctccagcgacggtgaaggcaccatgtcccgcccggcc
tcggtggacggcagccctgtgagtcccagcaccaacagaacccacgcccaccggcatcgg
ggcagcgcgcggctgcaccccccgctcaaccacagccgctccatccccatgccagcttcc
cgctgctcgccttcggccaccagcccggtcagtctgtcatccagcagcaccagtggccat
ggctccacctcagattgtctcttcccacggcggtctagtgcttcggtgtctggttccccc
agcgatggcggtttcgtctcctcggatgagtatggctccagtccctgcgatttccggagt
tccttccgcagtgtcactccggattccgtgggtcacaccccaccggcccgcggtgaggag
gagctgagcaactatatctgcatgggcggcaaggggccctccaccctgaccgcccccaac
ggtcactatattttgtctcggggtggcaatggccaccgctacaccccaggaacaggcttg
ggcacgagtccagccttggctggggatgaagcagccagtgctgccgatctggataatcgg
ttccgaaagagaactcactcggcaggcacatccccttccatttcccaccagaagaccccg
tctcagtcctcagtggcttccattgaggagtatacagagatgatgcctgtctacccacca
ggaggtggcagtggaggccgactgccgggacacaggcactccgccttcgtgcccacccat
tcctaccctgaggagggtctggaaatgcacctcttggagcgtcgggggggccaccatcgc
ccagaaagctccaccctccacagtgatgatggctacatgcccatgtccccaggggtggcc
ccagtgcccagcagccgaaagggcagtggagactatatgcccatgagccccaagagcgtg
tctgccccacagcagatcatcaaccccatcagacgccatccccagagagtggaccccaat
ggctacatgatgatgtcccccagcagcagctactcccctgacattggaggtggccctggc
agcagcagcagcagggctgtcccttctgggagcagctatggaaagctgtggacaaacggg
gtagggggccaccacgctcatgtcttgcctcaccccaaaccccctgtggaaagcagcagt
ggcaagctcttgccttgcacaggtgactacatgaacatgtcgccagtgggggactccaac
accagcagcccctctgactgctactacggccctgaggacccccagcacaagccagtcctc
tcctactactcattgccaagatcctttaagcacacccagctccctggggagctggaggag
ggtgcccgacatcagcaccttcgcctttccgctagctctggtcgccttctctatgctgca
acagtggaagattcttcctcctccaccagcagcgatagcctgggtgggggatattgtggg
gctaggatggagcccagccttccacattcccaccatcaggttctgcagcctcatctgcct
cgaaaggtggactcagctgctcagaccaatagccgcctggcccggcccacgaggctgtcc
ctgggggatcccaaggccagcaccttacctcgggctggagagcagcagcagcagcagcag
cagcagcagcccctgctgcaccctccggagcccaagagcccaggggaatatgtgaatatt
gaatttgggagtgatcagcctggctacttgtctggccctgtggcctcccacagctcacct
tctgtcaggtgtccatcccaactccagccagctcccagagaggaagagactggcactgag
gagtacatgaagatggacttgaggccaggccggagggcagcctggcaggagagcactggg
gttgaggtgggcagagtgggccctgcaccttctggggctgctagcatttgcaggcctacc
cgagcagtgcccagcagccggggtgactacatgaccatgcagatgggttgtccccgtcag
agctacgtggacacctcaccagttgcccctgtgagctatgctgacatgcggacaggcatt
gctgcagaggaggttagcctgcccagggccaccatggctgctgcctcctcagcctcagca
gcctctgcctcccctgctgggcctcaaggggcagcagagctggctgcccaatcatccctg
ctgggggaaccgcaaggacctgggggcatgagtgcctttaccccggtgaacctcagtcct
aaccgcaaccagagtgccaaagtgatccgtgcagacgcacaagggtgccggaggaggcat
agctccgagaccttctcctcaacacccagtgccacccgggtgggcaacacggtgcccttt
ggagcaggggcagcaggagggggcagtggcggtagcagcagcagcaaggatgtaaaacgc
cacagctctgcttcctttgagaacgtgtggctgaggcctggggagcttgggggagccccc
aaggagccagcccaactgtgcggggctgccggggatttggagaatggtcttaattacata
gacctggatttggtcaaggacatcaaacaatgccctcaggagcgaacccctcaaccacag
cctcccccacccccatccccaccctctcatcaacccctgggcagcggtgagaacagctcc
accccccgctccagtgaggatttaagcacctatgccagcatcagtttccagaagcagcca
gaggaccgtcagtag

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