Streptomyces broussonetiae: GQF42_37630
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Entry
GQF42_37630 CDS
T07359
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
sbro
Streptomyces broussonetiae
Pathway
sbro00909
Sesquiterpenoid and triterpenoid biosynthesis
sbro01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
sbro00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
GQF42_37630 (shc)
Enzymes [BR:
sbro01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
GQF42_37630 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
GQF42_37630 (shc)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
TED_complement
PGM1_C
Motif
Other DBs
NCBI-ProteinID:
QHA08233
UniProt:
A0A6I6N5U3
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All DBs
Position
8247440..8249464
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AA seq
674 aa
AA seq
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MTATTDGSTGATLPSHAAAASDTTLSTPEAAGVHQAATRAARRATDFLLARQDAQGWWKG
DLETNVTMDAEDLLLRQFLGIRDEKTTQAAAMFIRSEQREDGTWASFYKGPGELSTTIEA
YVALRLAGDAPDEAHMAKASAWIRERGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPASPNPPRPLAPVTS
WEGAFQRLDKGLHQLRKVVPRRLRRAAMDSAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMREGIASLDRFAVWREDGSRMIEACQSPVWDTCLAAIALVDAGLPADHPQ
LVKAADWMLGEEIVRPGDWAVKRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVGHHD
PERMDKAIARAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQESNGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLESIQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGEQDSK
AVERGVQWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
GLLARKPHSEVKVG
NT seq
2025 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggggcgaccctgccgtcccacgcggccgcggcc
agcgacaccactctcagcacccccgaggcggccggggtacaccaagccgccacacgcgcc
gcccggcgcgccaccgacttcctgctggcacggcaggacgcccagggctggtggaagggc
gacctcgagaccaacgtcaccatggacgccgaggacctgctgctccgtcagttcctgggg
atccgtgacgagaagaccacgcaggccgccgcgatgttcatccgcagcgagcagcgcgag
gacggcacctgggcctccttctacaagggcccgggggaactgtccaccaccatcgaggcg
tacgtcgccctgcgcctggccggcgacgcgcccgacgaggcgcacatggcgaaagcatcc
gcctggatccgtgagcgtggcgggatcgccgcctcccgtgtcttcacccggatctggctc
gccctgttcggctggtggaagtgggaggacctgcccgaactcccgccggaactgatctac
ttcccgacctggatgccgctcaacatctacgacttcggctgctgggcccggcagacgatc
gtgccgctgaccgtcgtctcggccaagcgtccggtgcgcccggcgcccttcccgctggac
gagctgcacaccgacccggccagccccaacccgcccaggccgcttgctccggtgacgagt
tgggagggcgccttccagcggctggacaaggggctgcaccagctgcgcaaggtcgtcccg
cgcaggctgcgcagggcggcgatggactcggccgcccgctggatcatcgagcggcaggag
aacgacggctgctggggcggcatccagccgccggccgtgtactcggtcatcgccctgcac
ctgctcggctacgacctcgagcaccccgtgatgcgcgagggcatcgcctcgctggaccgt
ttcgccgtgtggcgcgaggacggctcccggatgatcgaggcctgccagtccccggtgtgg
gacacctgcctcgccgccatcgcgcttgtcgacgcggggctgcccgccgatcatccgcaa
ctggtcaaggcggccgactggatgctcggcgaggagatcgtccggcccggggactgggcc
gtgaagcgccccggactgccgccgggcggctgggcgttcgagttccacaacgacaactac
ccggacatcgacgacaccgccgaggtcgcgctcgcgctgcgccgggtcggccaccacgac
cccgagcgcatggacaaggccattgcgcgggcggtgcgctggaacctggggatgcagtcg
aagaacggcgcctggggcgccttcgacgtcgacaacaccagcccgttccccaaccggctg
ccgttctgcgacttcggcgaggtcatcgacccgccgtcggcggacgtcaccgcgcacgtc
gtggagatgctcgccgccgagggtctcgcccacgatccgcgcacccggcgcggcatcgac
tggctgctcgccgaacaggagtcgaacggctcgtggttcggccgctggggcgtcaactac
atctacggcaccgggtcggtggtccccgccctgaccgcagccgggctgcccggctcgcac
ccggcgatccggcgggccgtggcctggctggagagcatccagaacgacgacggcggctgg
ggcgaggacctgcgctcctacaagtacgtcaaggagtggagcggtcgtggcgcctccacc
gcctcgcagaccgcgtgggcgctcatggcgctgctcgcggcgggggagcaggactccaag
gccgtcgagcgcggtgtgcagtggctggccgacacccagcgggaggacggcagctgggac
gagccgtacttcacgggcaccggcttcccctgggacttctccatcaactaccacctgtac
cggcaggtcttcccgctcaccgcgctcggccggtacctgcacggcgacccgttcgagcgt
ggcctgctcgccagaaaaccccactccgaggtcaaggtgggctga
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