Streptomyces cadmiisoli: DN051_14020
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Entry
DN051_14020 CDS
T07301
Symbol
kgd
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scad
Streptomyces cadmiisoli
Pathway
scad00020
Citrate cycle (TCA cycle)
scad00630
Glyoxylate and dicarboxylate metabolism
scad00785
Lipoic acid metabolism
scad01100
Metabolic pathways
scad01110
Biosynthesis of secondary metabolites
scad01120
Microbial metabolism in diverse environments
scad01200
Carbon metabolism
scad01210
2-Oxocarboxylic acid metabolism
Module
scad_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scad_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
DN051_14020 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
DN051_14020 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DN051_14020 (kgd)
Enzymes [BR:
scad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
DN051_14020 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
DN051_14020 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
DN051_14020 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
DN051_14020 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AWW42440
UniProt:
A0A2Z4JBS8
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All DBs
Position
3341287..3345096
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AA seq
1269 aa
AA seq
DB search
MSPESPSNASSSATLRAGGASTTDTDSAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRA
WWDFFADYKPGAPAPAAAETPTAPAPAPVAPAAPAAPAAPKPAPAAPAPAQAAAPAAPAK
AAAPAPAPAAKPQPRAAAPAAPAAEAPQGPELITLRGPAAAVAKNMNASLELPTATSVRA
VPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWSFGQKDGKPTLVK
PPHINLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDNKLTMDDFTG
VTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGAMDYPAEFQGTSQDTLNKLGISKVMTLTS
TYDHRVIQGAASGEFLRQVANLLLGENGFYDDIFESLRIPYEPVRWLKDIDASHDDDVTK
AARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSL
MKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRIERPHTKPEREEQLRILRRLNAA
EAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANI
VGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLTANPSHLEAVD
PVLEGVARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHV
VINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKD
VVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQ
DYQGQLEKVFTEVREATSQPASVETPDTQAEFPVAVNTAVSSEIVKRIAESQVNIPDHIT
VHPRLLPQLQRRATMVEDGTIDWGMGETLAVGSLLLEGVPVRLAGQDSQRGTFGQRHAVI
IDRTTGDEYTPLQYLSEDQARLTVYNSLLSEYAAMGFEYGYSLARPDALVMWEAQFGDFV
NGAQTVVDEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAM
PTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKADEFTSGQFRPVIGDASVDP
AAVRKVVFCAGKVYYDLEAERQKRGATDTAIIRIERLYPLPGAELQAEIKKYPNAEKYLW
AQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQE
QLVREVFEA
NT seq
3810 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccagagtccccgagtaacgcatcgagttccgccacccttcgggcgggcggtgcc
tccacgaccgacaccgattcagcgggcaagaaccccgctgcggcgttcggtcccaatgag
tggctcgtcgatgagatctatcagcagtacctccaggacccgaattcggtagaccgtgcc
tggtgggacttcttcgccgactacaagccgggagcgcccgctccggcggccgcggagacc
ccgacggccccggcccccgccccggtggctccggccgcgcccgccgcacccgcggccccg
aagcccgccccggccgctccggcaccggcgcaggccgccgcaccggccgccccggcgaag
gccgcggcaccggctcccgcgccggccgccaagccgcagccccgggccgccgcccccgcc
gcgcccgcggccgaggcgccccagggccccgagctgatcacgctgcgcggccccgccgcc
gcggtcgccaagaacatgaacgcctcgctggagctgcccacggccacgtccgtgcgcgcg
gtcccggtgaagctgctgttcgacaaccgcatcgtgatcaacaaccacctcaagcgggcc
cggggcgggaagatctccttcacgcacctgatcggctacgcgatggtgcaggccatcaag
gccatgccgtcgatgaactggtcgttcggccagaaggacggcaagccgaccctcgtcaag
ccgccgcacatcaacctcggcctcgccatcgacctggtcaagccgaacggcgaccgccag
ctggtcgtcgcggcgatcaagaaggccgagaccctgaacttcttcgagttctggcaggcc
tacgaggacatcgtccgtcgcgcccgcgacaacaagctgacgatggacgacttcaccggt
gtcacggtctcactgaccaaccccggcggcctcggcaccgtccactcggtgccgcgtctg
atgcccggccagtcggtgatcatgggcgtcggcgccatggactacccggcggagttccag
ggcacctcgcaggacaccctgaacaagctcggcatctccaaggtcatgacgctcacgtcg
acctacgaccaccgggtgatccagggcgccgcctccggcgagttcctccgccaggtcgcg
aacctcctgctcggcgagaacggcttctacgacgacatcttcgagtcgctgcgcatcccc
tacgagccggtccgctggctcaaggacatcgacgccagccacgacgacgacgtcaccaag
gccgcccgggtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgac
accgacccgctggagtaccgccagcgcaagcaccccgacctggacatcaccgagcacggc
ctgaccctgtgggacctggagcgcgagttcgccgtcggcggcttcgccggcaagtccctg
atgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcgtc
gagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgcatcgagcgc
ccgcacaccaagccggagcgcgaggagcagctgcgcatcctgcgccgtctgaacgccgcc
gaggcgttcgagaccttcctccagacgaagtacgtcggccagaagcgcttctcgctggag
ggcggcgagtccgtcatcccgctgctggacgcggtgctggactcggcggccgagtcccgc
ctggacgaggtcgtcatcggcatggcccaccggggccgcctgaacgtcctcgcgaacatc
gtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcg
atgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggcctg
gacggcgagcagatcaaggtctcgctcaccgccaacccctcgcacctggaggcggtcgac
ccggttctggagggcgtcgcccgcgccaagcaggacatcatcaacaagggcggcacggac
ttcaccgtcctgccggtggccctgcacggcgacgcggccttcgcgggccagggcgtggtg
gccgagaccctgaacatgtctcagctgcgcggctaccgcaccggcggcacggtccacgtg
gtcatcaacaaccaggtcggcttcaccgcggcccccgagtcctcgcgctcctcgatgtac
gcgacggacgtggcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccg
gaggccgtggtccgcgtcgcgcggctggccttcgagttccgccaggcgttcaacaaggac
gtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggcc
ttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctac
accgagtccctgatcggtcgcggtgacatcaccctggaagaggccgagcaggcgctccag
gactaccagggccagctggagaaggtcttcacggaggtccgcgaggccacctcgcagccg
gcgtcggtggagaccccggacacccaggccgaattcccggtcgcggtgaacaccgccgtc
tcctcggagatcgtcaagcggatcgccgagtcccaggtcaacatccccgaccacatcacc
gtccacccgcgtctgctgccgcagctgcagcgccgggcgacgatggtcgaggacggcacc
atcgactggggcatgggcgagaccctcgcggtcggctccctcctgctggagggcgtcccg
gtccggctggcgggccaggactcgcagcgcggtacgttcggccagcggcacgcggtcatc
atcgaccgcaccacgggcgacgagtacacgccgttgcagtacctgtccgaggaccaggcg
cgcctgaccgtctacaactcgctgctctccgagtacgcggcgatgggcttcgagtacggc
tactcgctggcccgtccggacgcgctggtgatgtgggaggcgcagttcggcgacttcgtc
aacggcgcgcagacggtcgtggacgagttcatctcgtccgcggagcagaagtgggcccag
acgagcggcgtggtcctgctgctgccgcacggttacgagggccagggcccggaccactcg
tccgcccgcccggagcgcttcctccagctgtgcgcgcagaacaacatgacggtcgccatg
ccgaccctcccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccac
aagccgctggtggtcttcacgccgaagtcgatgctgcgtctgaaggccgcggcgtcgaag
gcggacgagttcacctcgggccagttccggccggtcatcggtgacgcgtcggtggacccg
gcggcggtcaggaaggtcgtcttctgcgccggcaaggtctactacgacctggaggccgag
cgtcagaagcgcggcgcgacggacaccgcgatcatccgtatcgagcgcctctacccgctg
ccgggtgcggagctccaggcggagatcaagaagtacccgaacgccgagaagtacctgtgg
gcgcaggaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgac
cacctggacctggcggtcggcgccgacgtcccgcacggcgagcgcctgcgccgcatctcg
cggccgcacggctcgtctcccgccgtcggttccgcgaagcggcaccaggcggagcaggag
cagctggtgcgtgaggtgttcgaggcatag
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