Streptomyces caniscabiei: IHE65_31545
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Entry
IHE65_31545 CDS
T08931
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
scae
Streptomyces caniscabiei
Pathway
scae00010
Glycolysis / Gluconeogenesis
scae00020
Citrate cycle (TCA cycle)
scae00620
Pyruvate metabolism
scae00785
Lipoic acid metabolism
scae01100
Metabolic pathways
scae01110
Biosynthesis of secondary metabolites
scae01120
Microbial metabolism in diverse environments
scae01200
Carbon metabolism
scae01210
2-Oxocarboxylic acid metabolism
Module
scae_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
scae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
IHE65_31545 (aceE)
00020 Citrate cycle (TCA cycle)
IHE65_31545 (aceE)
00620 Pyruvate metabolism
IHE65_31545 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IHE65_31545 (aceE)
Enzymes [BR:
scae01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
IHE65_31545 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
WEO27328
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All DBs
Position
complement(7104898..7107645)
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AA seq
915 aa
AA seq
DB search
MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIPTKAEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAFMLDRLDERQLDAFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIFQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEPESLGQLTIAAREHLDNLTFVVNCNLQRLDGPVRGNGKVIQELESVFRGA
GWNVIKLVWDRSWDPLLAQDRDGVLVNRMNTTPDGQYQTYATETGAYIRDHFFGDDHRLR
AMVENMTDDQILHLGRGGHDHRKIYAAYKAAYEHKGQPTVILAKTVKGWTLGPNFEGRNA
THQMKKLTVADLKGFRDRLHLPISDKELESGAPPYYHPGRDSEEIQYMHDRRKGLGGYVP
TRVVRAKPLPLPEDKTYASVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMSDQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAYGYEIAHIVKDGLRRMYGETADGKPGEDVFYYLTVYNEPIQH
PAEPADVDVEGILKGIHRHQAGEAGSIPAQIIASGVAVPWAVEAQRILAADWNVKADVWS
ATSWNELRREAVEVERHNLLHPEEEQQVPYVTKKLGSAEGPFVAVSDWMRSVPDQISRWV
PGTYQSLGADGFGFADTRGAARRFFHIDPQSIVVAVLTELAREGKVDRSVLKQAIDRYQL
LDVAAADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaatccgatcatcattggcggccttccgagtcaggtccct
gacttcgatcccgaggagacccaggagtggctcgactcgctcgacgccgccgtggacgag
cgcggccgtgagcgcgcgcgctacctgatgctccggctcatcgagcgggcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactatgtcaacaccatcccgaccaaggcc
gagccgttcttccccggcaacgaggagatcgagcggaagatcctcaacgcgacccgctgg
aacgccgccgtgatggtctcgcgcgcgcagcggcccgggatcggcgtcggcggtcacatc
gcgaccttcgcgtcctccgcctccctctacgacgtgggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccatgcctcgcccggcatc
tacgcccgcgcgttcatgctcgaccggctagacgagcggcagctggacgcgttccgccag
gagaagtccaaggcgccgtacgggctgtccagctacccgcacccgcgtctgatgccggac
ttctgggagttcccgacggtgtccatgggcctcggtccgctgggcgcgatcttccaggcg
cggatgaaccggtacatggaggcgcgcgggatcgcggacacctccaagtcgcatgtctgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctcggccagctcacgatcgcc
gcccgcgagcacctcgacaacctcaccttcgtcgtgaactgcaacctccagcgcctcgac
ggcccggtgcgcggcaacggcaaggtcatccaggagctggagtcggtcttccggggcgcc
ggctggaacgtgatcaagctggtctgggaccgctcctgggacccgctgctcgcacaggac
cgcgacggtgtgctggtcaaccggatgaacaccacgccggacggccagtaccagacgtac
gccacggagaccggggcgtacatccgcgaccacttcttcggtgacgaccaccggctgcgc
gcgatggtcgagaacatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
caccgcaagatctacgcggcgtacaaggcggcgtacgagcacaagggccagccgacggtc
atcctggcgaagacggtcaagggctggaccctcggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgccgacctcaagggcttccgcgaccgactgcac
ctgccgatctccgacaaggagctggagagcggggccccgccgtactaccaccccgggcgg
gactccgaggagatccagtacatgcacgaccgccgcaaggggctcggcgggtacgtcccg
acgcgtgtcgtgcgtgcgaagcctctgccgctgcccgaggacaagacgtacgcgagtgtg
aagaagggttccggtcagcagtcgatcgccacgaccatggcgttcgtacggttgctgaag
gacctcatgcgggacaaggagatcggcaagcggttcgtgctgatcgcccccgacgagtac
cgcaccttcggtatggactccttcttcccgagtgcgaagatctacaacccgctcggccag
cagtacgaggcggtcgaccgcgatctgctgctcgcgtacaaggagtcgccgaccgggcag
atgctgcacgacggcatctcggaggcgggctgcacggcgtcgctgatcgccgccggttcg
gcctacgccacgcacggcgagccgctcatcccggtctacgtcttctactcgatgttcggc
ttccagcgcaccggtgaccagttctggcagatgtccgaccagctggcccgcggcttcgtt
ctgggcgccaccgccggccgtacgaccctgaccggtgagggcctccagcacgcggacggg
cactcgcagctgctggcgtccaccaacccgggctgtgtcgcctacgacccggcgtacggg
tacgagatcgcgcacatcgtgaaggacggtctgcgccggatgtacggcgagaccgcggac
ggcaagccgggcgaggacgtcttctactacctcaccgtctacaacgagccgatccagcac
ccggccgagccggcggacgtggacgtggagggcatcctcaagggcatccaccgccaccag
gccggcgaggcgggctccatccccgcgcagatcatcgcctccggtgtcgcggtgccgtgg
gcggtggaggcccagcggatcctcgccgccgactggaacgtcaaggcggacgtctggtcg
gcgacctcctggaacgagctgcgccgcgaggccgtcgaggtggagcggcacaacctgctg
caccccgaggaggagcagcaggtcccctacgtgacgaagaagctcggcagcgccgagggg
ccgttcgtggccgtctccgactggatgcggtcggtgccggaccagatctcgcgctgggtg
ccgggcacgtaccagtcgctgggcgcggacggcttcggcttcgcggacacccggggtgcg
gcgcggcgtttcttccacatcgacccgcagtcgatcgtggtcgcggtgctgaccgagctg
gcccgcgagggcaaggtcgaccgctcggtgctcaagcaggccatcgaccggtaccagctg
ctcgacgtggccgcggcggacccgggagcggccggcggcgacgcctag
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