KEGG   Streptomyces castrisilvae: P8A18_24650
Entry
P8A18_24650       CDS       T10534                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
scat  Streptomyces castrisilvae
Pathway
scat03030  DNA replication
scat03410  Base excision repair
scat03420  Nucleotide excision repair
scat03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:scat00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    P8A18_24650 (ligA)
   03410 Base excision repair
    P8A18_24650 (ligA)
   03420 Nucleotide excision repair
    P8A18_24650 (ligA)
   03430 Mismatch repair
    P8A18_24650 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:scat03032]
    P8A18_24650 (ligA)
   03400 DNA repair and recombination proteins [BR:scat03400]
    P8A18_24650 (ligA)
Enzymes [BR:scat01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     P8A18_24650 (ligA)
DNA replication proteins [BR:scat03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     P8A18_24650 (ligA)
DNA repair and recombination proteins [BR:scat03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     P8A18_24650 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     P8A18_24650 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     P8A18_24650 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      P8A18_24650 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT Nlig-Ia HHH_5 HHH Zn_ribbon_TFIIB zf-IS66 DUF7575
Other DBs
NCBI-ProteinID: WLQ36423
LinkDB
Position
5634963..5637191
AA seq 742 aa
MAGEEQTAVPVEARDRHDLLAEQIEEHRFRYYVNDQPVVSDAEFDRLMRELEGLEEAHPS
LRSPDSPTQKVAGPYRTQFTSVEHREPMLSLDNAFDDEELSAWGERVARDVGRPGYHFLC
ELKIDGLAVNLTYENGVLTRAATRGDGRTGEDITPNVRTIADIPHRLKGDRIPPLVEIRG
EVFFPMEGFEELNARLVEADDKPFANPRNAAAGSLRQKDPKVTATRPLHMVVHGIGAREG
FDIDCLSHAYELLREWGLPTAKYNKVVDSLAGVREFIAYFGEHRHSVEHEIDGVVVKLDE
IPLQGRLGSTSRAPRWAIAWKYAPEEVNTKLVNIRVGVGRTGRVTPYAQVEPVVVAGSEV
EFATLHNQNVVRAKGVLIGDTVVLRKAGDVIPEILGPVVDLRDGTEQAFVMPTHCPECGK
ELKPMKEADVDVRCPNARSCPAQLRERVSYLAGRKCLDIDHFGYVVAAALTRPLEPAEPP
LRDEGDLFGLTVEELLPIRAYVLDQDSGLPKRDPKTGEEKTALVFANQQGEPKKNALAML
DAIAAAKQAPLARVLTGLSIRHVGPVAARELARQFRSIDRIEEATEQELADADGVGPIIA
ASVKQWFAEDWHREILRKWREAGVRMEDEGAGEDEGPRPLEGLTVVVTGTLTGHTRDGAK
EALQSRGAKVTGSVSKKTAFVVVGDNPGSKYDKAVQLKVPVLDETGFAVLLDQGPDAARE
AAVPAEGRAAEPAPEEDAAPGE
NT seq 2229 nt   +upstreamnt  +downstreamnt
atggccggcgaagagcagacagcggtgccagtggaggcgcgggatcggcacgatctcctc
gcggaacagatcgaggagcaccgcttccggtattacgtgaacgaccagccggtcgtcagc
gacgccgagttcgaccggctgatgcgcgagctggagggactggaggaggcccacccctcg
ctgcgctcgcccgactcgccgacccagaaggtcgccggcccctaccgcacgcagttcacc
tccgtcgagcaccgcgagccgatgctctccctggacaacgccttcgacgacgaggagctg
tccgcctggggcgagcgcgtcgcccgtgacgtgggccgccccggctaccacttcctgtgc
gagctgaagatcgacggcctcgccgtcaacctcacctacgagaacggcgtgctgacgcgg
gcggcgacccgcggcgacggccgcaccggcgaggacatcacgcccaacgtccgcaccatc
gccgacatcccgcaccggctgaagggcgaccggatcccgccgctggtcgagatccgcggc
gaggtcttcttcccgatggaagggttcgaggagctgaacgcccggctggtcgaggccgac
gacaagcccttcgccaacccgcgcaacgcggcggccggttcgctgcgccagaaggacccc
aaggtcaccgccacccgcccgctgcacatggtggtgcacggcatcggcgcccgcgagggc
ttcgacatcgactgcctctcgcacgcctacgagctgctgcgcgagtggggcctgcccacc
gccaagtacaacaaggtggtcgactccctcgccggcgtacgggagttcatcgcgtacttc
ggcgagcaccggcactccgtggaacacgagatcgacggcgtcgtcgtcaagctggacgag
atcccgctccagggccggctgggctccacctcgcgcgccccgcgctgggccatcgcctgg
aagtacgccccggaggaggtcaacaccaagctggtcaacatccgcgtcggcgtcggccgc
accggccgcgtcaccccgtacgcccaggtcgagccggtcgtggtggccggctccgaggtc
gagttcgccaccctccacaaccagaacgtggtccgcgccaagggcgtgctcatcggcgac
acggtggtgctccgcaaggccggtgacgtcatcccggagatcctcgggcccgtcgtcgac
ctccgcgacggcacggagcaggcgttcgtcatgccgacccactgccccgagtgcgggaag
gagctgaagcccatgaaggaggcggacgtcgacgtccgctgccccaacgcccgctcctgc
ccggcccagctgcgcgagcgcgtctcctacctcgccggccgcaagtgcctggacatcgac
cacttcggatacgtggtcgccgcggccctcacccggccgctggagcccgccgagccgccg
ctgcgcgacgagggggacctcttcgggctgaccgtggaggagctgctgccgatccgggcc
tacgtcctcgaccaggacagcgggctgcccaagcgcgacccgaagaccggcgaggagaag
acggccctggtcttcgccaaccagcagggcgagcccaagaagaacgccctcgccatgctg
gacgccatcgccgccgccaagcaggccccgctggcccgcgtcctcaccgggctctccatc
cgccacgtcggcccggtcgccgcccgtgagctggcccgtcagttccggtccatcgaccgc
atcgaggaggccaccgagcaggagctcgccgacgcggacggggtcgggccgatcatcgcc
gcctcggtcaagcagtggttcgccgaggactggcaccgcgagatcctgcgcaagtggcgc
gaggccggagtccggatggaggacgagggggccggcgaggacgaggggccccggccgctc
gaagggctcaccgtcgtcgtcacgggcacattgaccggccacaccagggacggcgcgaaa
gaggccctccagagccggggcgcgaaggtcaccggttccgtctcgaagaagaccgccttc
gtcgtggtcggcgacaaccccggctccaagtacgacaaggcggtgcagctgaaggtcccc
gtgctggacgagaccggcttcgccgtgctgctcgaccagggcccggacgcggcccgcgag
gcagcggtcccggccgagggccgggccgcggagcccgcgccggaggaggacgccgcaccc
ggagagtga

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