Streptomyces cavourensis: CVT27_04880
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Entry
CVT27_04880 CDS
T07023
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
scav
Streptomyces cavourensis
Pathway
scav00270
Cysteine and methionine metabolism
scav00450
Selenocompound metabolism
scav00670
One carbon pool by folate
scav01100
Metabolic pathways
scav01110
Biosynthesis of secondary metabolites
scav01230
Biosynthesis of amino acids
scav04980
Cobalamin transport and metabolism
scav04981
Folate transport and metabolism
Module
scav_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
scav00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CVT27_04880 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
CVT27_04880 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
CVT27_04880 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
CVT27_04880 (metH)
04980 Cobalamin transport and metabolism
CVT27_04880 (metH)
Enzymes [BR:
scav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
CVT27_04880 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
DUF2497
Motif
Other DBs
NCBI-ProteinID:
ATY94878
LinkDB
All DBs
Position
complement(1106888..1110400)
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AA seq
1170 aa
AA seq
DB search
MASLPTPAPDSRTRAAALREALATRVVVADGAMGTMLQAQDPTLDDFEGLEGCNEILNLT
RPDIVRTVHEEYFAVGVDCVETNTFGANHSAANEYEIAHRIHELSESGARIAREVADEFA
AKDGRQRWVLGSIGPGTKLPSLGHITYDILRDGYQKNAEGLLAGGSDALIVETTQDLLQT
KASIIGARRAMDALGIDVPLICSLAFETTGVMLLGSEIGAALTALEPLGIDLIGLNCSTG
PDEMSEHLRYLARHSRTPLMCMPNAGLPVLTKDGAHFPLGPDGLADSQELFVRDYGLSLI
GGCCGTTPAHMKAVVERAQGLTPPEREPRPEPGAASLYQHVPFRQDTAYLAIGERTNANG
SKKFREAMLEARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMTELAGRFATASTLP
IVLDSTELDVLRAGLEQLGGRAVLNSVNYEDGDGPDSRFAQVSALAAEHGAALIALTIDE
EGQARTIEHKVAIAERLIADLTTNWGIRESDILIDTLTFTICTGQEESRGDGIATIGAIR
ELKKRHPDVQTTLGLSNISFGLNPAARVVLNSVFLDECVKAGLDSAIVHASKILPIARLE
EEQVKVALDLIYDRRAEGYDPLQKLMELFEGVNMKSMKAGKAEELMALPLDERLQRRIID
GEKNGLEADLDEALQTTPALDIVNNTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKSAVA
HLEPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILEA
AEEHRADVIGMSGLLVKSTVIMKENLQELNQRKMAADFPVILGGAALTRAYVEQDLHEIY
EGEVRYARDAFEGLRLMDALIGVKRGVPGAALPELKQRRVPKKDVPVLEVQEPEGSVRSD
VSTTNPIPEPPFWGTRVIKGIPLKEYASWLDEGALFKGQWGLKQARTGDGPTYEELVETE
GRPHLRGWLDHLQSNNLLEAAVVYGYFPCVSKGEDLILLHEDGSERTRFTFPRQRRGRRL
CLADFFRPEESGERDVIGLQVVTVGSRIGEATAELFAANSYRDYLELHGLSVQLAEALAE
YWHARVRSELGFGGEDPAEVEDMFALKYRGARFSLGYGACPDLEDRAKIADLLRPERIGV
ELSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3513 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgttgccgacacccgcccctgacagccggacccgcgcagccgccctgcgcgag
gcgctcgccacccgggtggtggtggccgacggtgccatgggcaccatgctccaggcgcag
gacccgaccctcgacgacttcgagggcctcgaaggctgcaacgagatcctcaacctgacc
cgcccggacatcgtgcgcacggtccacgaggagtacttcgcggtcggcgtcgactgcgtg
gagaccaacaccttcggtgccaaccactccgccgccaacgagtacgagatcgcgcaccgg
atccacgagctgtccgagtccggcgcccgcatcgcccgcgaggtcgcggacgagttcgcc
gccaaggacggccgccagcggtgggtcctcggctcgatcggccccggcaccaagctgccc
tcgctcggccacatcacgtacgacatcctgcgcgacggctaccagaagaacgccgaaggc
ctcctggcgggcggctccgacgccctgatcgtcgagaccacccaggacctgctccagacc
aaggccagcatcatcggcgcccgccgggccatggacgccctcggcatcgacgtgcccctg
atctgttccctggccttcgagaccaccggcgtcatgctgctcggctccgagatcggcgcc
gccctgaccgccctggagccgctcggcatcgacctgatcgggctgaactgctcgaccggc
cccgacgagatgagcgagcacctgcgctatctcgcccgccactcccgtacgcccctgatg
tgcatgcccaacgccggcctgcccgtcctcaccaaggacggcgcgcacttcccgctcggc
cccgacggcctcgcggactcccaggagctgttcgtccgcgactacggcctctccctgatc
ggcggctgctgcggtacgaccccggcccacatgaaggccgtcgtggagcgggcccagggg
ctcaccccgcccgagcgcgagccgcgccccgagcccggcgccgcctcgctctaccagcac
gtgccgttccgccaggacaccgcctacctggcgatcggggagcgcaccaacgccaacggc
tccaagaagttccgcgaggccatgctggaggcccgctgggacgactgcgtggagatggcc
cgcgaccagatccgcgagggcgcccacatgctcgacctctgcgtcgactacgtgggccgc
gacggcgtcgcggacatgaccgagctggccggccgcttcgccaccgcctccaccctgccg
atcgtgctggactccaccgagctggacgtcctgcgcgccgggctggagcagctcggcggc
cgggccgtgctcaactcggtcaactacgaggacggcgacggccccgactcccggttcgcg
caggtcagcgccctggccgccgagcacggcgccgccctgatcgcgctgacgatcgacgag
gagggccaggcccgcaccatcgagcacaaggtcgccatcgcggagcggctgatcgcggac
ctcaccaccaactggggcatccgcgagtccgacatcctcatcgacaccctgaccttcacc
atctgcaccggccaggaggagtcccggggcgacggcatcgccaccatcggggccatccgc
gagctgaagaagcgccacccggacgtccagaccacgctgggcctctccaacatctccttc
ggcctcaacccggccgcccgcgtcgtgctgaactccgtcttcctcgacgagtgcgtcaag
gcgggcctggactccgcgatcgtccacgcctccaagatcctgcccatcgcccggctggag
gaggagcaggtcaaggtcgccctcgacctgatctacgaccgccgcgccgagggctacgac
cccctccagaagctcatggagctgttcgagggcgtcaacatgaagtcgatgaaggcgggc
aaggccgaggagctgatggccctcccgctggacgagcggctccagcgccgcatcatcgac
ggcgagaagaacggcctggaggccgacctcgacgaggccctccagaccaccccggccctc
gacatcgtcaacaacaccctcctggagggcatgaaggtcgtcggtgagctgttcggctcc
ggccagatgcagctgccgttcgtcctccagtccgccgaggtcatgaagagcgcggtggcc
cacctggagccgcacatggagaagtccgacgacgagggcaagggcaccatcgtcctcgcc
accgtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctctccaac
aacggctacaacgtcgtcaacctcggcatcaagcagcccgtctccgcgatcctggaagcc
gccgaggagcaccgcgccgacgtcatcggcatgtccggtctcctggtcaagtccaccgtg
atcatgaaggagaacctccaggagctgaaccagcgcaagatggccgccgacttcccggtc
atcctcggcggcgccgcgctgacccgggcctacgtcgagcaggacctgcacgagatctac
gagggcgaggtgcgctacgcccgcgacgccttcgaggggctgcgcctcatggatgcgctc
atcggcgtcaagcgcggggtgccgggcgcggccctgcccgagctgaagcagcgccgggtc
cccaagaaggacgtccccgtgctggaggtccaggagcccgagggctcggtgcgctcggac
gtctccaccaccaacccgatccccgagccgccgttctggggcacccgcgtgatcaagggc
atcccgctcaaggagtacgcttcctggctggacgagggtgccctgttcaaggggcagtgg
ggcctcaagcaggccaggaccggggacggaccgacgtacgaggaactggtggagaccgag
ggccgcccgcacctgcgcggctggctcgaccacctccagtccaacaacctgctggaagcc
gccgtcgtctacggctacttcccctgcgtctccaagggcgaggacctgatcctcctccac
gaggacggctccgagcgcacccgcttcaccttcccgcgccagcgccgcggccgccgcctc
tgcctcgcggacttcttccgccccgaggagtccggcgagagggacgtcatcggcctccag
gtcgtcaccgtcggctcccggatcggggaggccaccgccgagctgttcgccgccaactcc
taccgggactacctggagctgcacggcctctccgtccagctcgcggaggccctggcggag
tactggcacgcccgggtccgcagcgagctgggcttcggcggcgaggacccggccgaggtg
gaggacatgttcgcgctgaagtaccggggcgcgcggttctcgctcggttacggggcctgc
cccgacctggaggaccgcgcgaagatcgcggacctgctgcggccggagcggatcggggtg
gagctgtccgaggagttccagctccacccggagcagtccaccgacgccatcgtcatccac
caccccgaggcgaagtacttcaacgcacggtaa
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