KEGG   Streptomyces cavourensis: CVT27_04880
Entry
CVT27_04880       CDS       T07023                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
scav  Streptomyces cavourensis
Pathway
scav00270  Cysteine and methionine metabolism
scav00450  Selenocompound metabolism
scav00670  One carbon pool by folate
scav01100  Metabolic pathways
scav01110  Biosynthesis of secondary metabolites
scav01230  Biosynthesis of amino acids
scav04980  Cobalamin transport and metabolism
scav04981  Folate transport and metabolism
Module
scav_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:scav00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CVT27_04880 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CVT27_04880 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CVT27_04880 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    CVT27_04880 (metH)
   04980 Cobalamin transport and metabolism
    CVT27_04880 (metH)
Enzymes [BR:scav01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CVT27_04880 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2 DUF2497
Other DBs
NCBI-ProteinID: ATY94878
LinkDB
Position
complement(1106888..1110400)
AA seq 1170 aa
MASLPTPAPDSRTRAAALREALATRVVVADGAMGTMLQAQDPTLDDFEGLEGCNEILNLT
RPDIVRTVHEEYFAVGVDCVETNTFGANHSAANEYEIAHRIHELSESGARIAREVADEFA
AKDGRQRWVLGSIGPGTKLPSLGHITYDILRDGYQKNAEGLLAGGSDALIVETTQDLLQT
KASIIGARRAMDALGIDVPLICSLAFETTGVMLLGSEIGAALTALEPLGIDLIGLNCSTG
PDEMSEHLRYLARHSRTPLMCMPNAGLPVLTKDGAHFPLGPDGLADSQELFVRDYGLSLI
GGCCGTTPAHMKAVVERAQGLTPPEREPRPEPGAASLYQHVPFRQDTAYLAIGERTNANG
SKKFREAMLEARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMTELAGRFATASTLP
IVLDSTELDVLRAGLEQLGGRAVLNSVNYEDGDGPDSRFAQVSALAAEHGAALIALTIDE
EGQARTIEHKVAIAERLIADLTTNWGIRESDILIDTLTFTICTGQEESRGDGIATIGAIR
ELKKRHPDVQTTLGLSNISFGLNPAARVVLNSVFLDECVKAGLDSAIVHASKILPIARLE
EEQVKVALDLIYDRRAEGYDPLQKLMELFEGVNMKSMKAGKAEELMALPLDERLQRRIID
GEKNGLEADLDEALQTTPALDIVNNTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKSAVA
HLEPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILEA
AEEHRADVIGMSGLLVKSTVIMKENLQELNQRKMAADFPVILGGAALTRAYVEQDLHEIY
EGEVRYARDAFEGLRLMDALIGVKRGVPGAALPELKQRRVPKKDVPVLEVQEPEGSVRSD
VSTTNPIPEPPFWGTRVIKGIPLKEYASWLDEGALFKGQWGLKQARTGDGPTYEELVETE
GRPHLRGWLDHLQSNNLLEAAVVYGYFPCVSKGEDLILLHEDGSERTRFTFPRQRRGRRL
CLADFFRPEESGERDVIGLQVVTVGSRIGEATAELFAANSYRDYLELHGLSVQLAEALAE
YWHARVRSELGFGGEDPAEVEDMFALKYRGARFSLGYGACPDLEDRAKIADLLRPERIGV
ELSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggcctcgttgccgacacccgcccctgacagccggacccgcgcagccgccctgcgcgag
gcgctcgccacccgggtggtggtggccgacggtgccatgggcaccatgctccaggcgcag
gacccgaccctcgacgacttcgagggcctcgaaggctgcaacgagatcctcaacctgacc
cgcccggacatcgtgcgcacggtccacgaggagtacttcgcggtcggcgtcgactgcgtg
gagaccaacaccttcggtgccaaccactccgccgccaacgagtacgagatcgcgcaccgg
atccacgagctgtccgagtccggcgcccgcatcgcccgcgaggtcgcggacgagttcgcc
gccaaggacggccgccagcggtgggtcctcggctcgatcggccccggcaccaagctgccc
tcgctcggccacatcacgtacgacatcctgcgcgacggctaccagaagaacgccgaaggc
ctcctggcgggcggctccgacgccctgatcgtcgagaccacccaggacctgctccagacc
aaggccagcatcatcggcgcccgccgggccatggacgccctcggcatcgacgtgcccctg
atctgttccctggccttcgagaccaccggcgtcatgctgctcggctccgagatcggcgcc
gccctgaccgccctggagccgctcggcatcgacctgatcgggctgaactgctcgaccggc
cccgacgagatgagcgagcacctgcgctatctcgcccgccactcccgtacgcccctgatg
tgcatgcccaacgccggcctgcccgtcctcaccaaggacggcgcgcacttcccgctcggc
cccgacggcctcgcggactcccaggagctgttcgtccgcgactacggcctctccctgatc
ggcggctgctgcggtacgaccccggcccacatgaaggccgtcgtggagcgggcccagggg
ctcaccccgcccgagcgcgagccgcgccccgagcccggcgccgcctcgctctaccagcac
gtgccgttccgccaggacaccgcctacctggcgatcggggagcgcaccaacgccaacggc
tccaagaagttccgcgaggccatgctggaggcccgctgggacgactgcgtggagatggcc
cgcgaccagatccgcgagggcgcccacatgctcgacctctgcgtcgactacgtgggccgc
gacggcgtcgcggacatgaccgagctggccggccgcttcgccaccgcctccaccctgccg
atcgtgctggactccaccgagctggacgtcctgcgcgccgggctggagcagctcggcggc
cgggccgtgctcaactcggtcaactacgaggacggcgacggccccgactcccggttcgcg
caggtcagcgccctggccgccgagcacggcgccgccctgatcgcgctgacgatcgacgag
gagggccaggcccgcaccatcgagcacaaggtcgccatcgcggagcggctgatcgcggac
ctcaccaccaactggggcatccgcgagtccgacatcctcatcgacaccctgaccttcacc
atctgcaccggccaggaggagtcccggggcgacggcatcgccaccatcggggccatccgc
gagctgaagaagcgccacccggacgtccagaccacgctgggcctctccaacatctccttc
ggcctcaacccggccgcccgcgtcgtgctgaactccgtcttcctcgacgagtgcgtcaag
gcgggcctggactccgcgatcgtccacgcctccaagatcctgcccatcgcccggctggag
gaggagcaggtcaaggtcgccctcgacctgatctacgaccgccgcgccgagggctacgac
cccctccagaagctcatggagctgttcgagggcgtcaacatgaagtcgatgaaggcgggc
aaggccgaggagctgatggccctcccgctggacgagcggctccagcgccgcatcatcgac
ggcgagaagaacggcctggaggccgacctcgacgaggccctccagaccaccccggccctc
gacatcgtcaacaacaccctcctggagggcatgaaggtcgtcggtgagctgttcggctcc
ggccagatgcagctgccgttcgtcctccagtccgccgaggtcatgaagagcgcggtggcc
cacctggagccgcacatggagaagtccgacgacgagggcaagggcaccatcgtcctcgcc
accgtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctctccaac
aacggctacaacgtcgtcaacctcggcatcaagcagcccgtctccgcgatcctggaagcc
gccgaggagcaccgcgccgacgtcatcggcatgtccggtctcctggtcaagtccaccgtg
atcatgaaggagaacctccaggagctgaaccagcgcaagatggccgccgacttcccggtc
atcctcggcggcgccgcgctgacccgggcctacgtcgagcaggacctgcacgagatctac
gagggcgaggtgcgctacgcccgcgacgccttcgaggggctgcgcctcatggatgcgctc
atcggcgtcaagcgcggggtgccgggcgcggccctgcccgagctgaagcagcgccgggtc
cccaagaaggacgtccccgtgctggaggtccaggagcccgagggctcggtgcgctcggac
gtctccaccaccaacccgatccccgagccgccgttctggggcacccgcgtgatcaagggc
atcccgctcaaggagtacgcttcctggctggacgagggtgccctgttcaaggggcagtgg
ggcctcaagcaggccaggaccggggacggaccgacgtacgaggaactggtggagaccgag
ggccgcccgcacctgcgcggctggctcgaccacctccagtccaacaacctgctggaagcc
gccgtcgtctacggctacttcccctgcgtctccaagggcgaggacctgatcctcctccac
gaggacggctccgagcgcacccgcttcaccttcccgcgccagcgccgcggccgccgcctc
tgcctcgcggacttcttccgccccgaggagtccggcgagagggacgtcatcggcctccag
gtcgtcaccgtcggctcccggatcggggaggccaccgccgagctgttcgccgccaactcc
taccgggactacctggagctgcacggcctctccgtccagctcgcggaggccctggcggag
tactggcacgcccgggtccgcagcgagctgggcttcggcggcgaggacccggccgaggtg
gaggacatgttcgcgctgaagtaccggggcgcgcggttctcgctcggttacggggcctgc
cccgacctggaggaccgcgcgaagatcgcggacctgctgcggccggagcggatcggggtg
gagctgtccgaggagttccagctccacccggagcagtccaccgacgccatcgtcatccac
caccccgaggcgaagtacttcaacgcacggtaa

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