Streptomyces cavourensis: CVT27_23620
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Entry
CVT27_23620 CDS
T07023
Symbol
kgd
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scav
Streptomyces cavourensis
Pathway
scav00020
Citrate cycle (TCA cycle)
scav00630
Glyoxylate and dicarboxylate metabolism
scav00785
Lipoic acid metabolism
scav01100
Metabolic pathways
scav01110
Biosynthesis of secondary metabolites
scav01120
Microbial metabolism in diverse environments
scav01200
Carbon metabolism
scav01210
2-Oxocarboxylic acid metabolism
Module
scav_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scav_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CVT27_23620 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
CVT27_23620 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CVT27_23620 (kgd)
Enzymes [BR:
scav01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CVT27_23620 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CVT27_23620 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CVT27_23620 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CVT27_23620 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ATY98113
LinkDB
All DBs
Position
complement(5283930..5287754)
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AA seq
1274 aa
AA seq
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MSSQSPSNSSISTDQASPGTDPAAAFGANEWLVDEIYQQYLQDPSSVDRAWWDFFADYKP
GSSGTADKPAPGAAASGAAATQAPAATTPAQSAAPAAAPAPSPAKPAAAAPAAPAPAKAA
PAAAPAKPAAAKPAAAPAKPKAKADEATEAPAGPEYVTLRGPSAAVAKNMNASLELPTAT
SVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMNYSFAEKDGKP
TLVKPDHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARIGKLGMD
DFTGVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNKLGISKVM
TLTSTYDHRVIQGAASGEFLRIVSQLLLGQNEFYDEIFKALRIPYEPVRWLTDIDASHDN
DVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLERDFAVGGFA
GKSMMKLRDILGVLRESYCRTTGIEFMHIQDPKQRKWLQDRVERPRAQQPEREEQLRILR
RLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMAHRGRLN
VLANIVGKSYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSH
LEAVDPVLEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTG
GTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLAFEFRQ
AFNKDVVIDLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIGRGDITLEEA
EQALQDFQGQLEKVFAEVREATSQPAAPHVPEPQAAFPVAVDTAVSAEVIKRIAESQVNI
PESITVHPRLMPQMQRRAASVENGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQ
RHAVLVDQVTGEDYTPLLYLTEDQARYNVYDSLLSEYAAMGFEYGYSLARPESLVIWEAQ
FGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDN
MTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKIEEFTSGGFRPVIGD
DTVKAEDVRKVVFVSGKLFYDLDAEREKRGDTETALIRLERLYPLPGAEIQAEIAKYPNA
EKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRH
QAEQTQLVNEVFEA
NT seq
3825 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagcatctcgaccgaccaagccagcccgggtacc
gacccggccgccgctttcggcgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggatcccagttcggtcgatcgcgcctggtgggacttcttcgccgactacaagccg
ggttcctccggcacggcggacaagcccgctcccggcgccgcagcctcgggggctgcggca
acccaggccccggccgccaccaccccggcgcagtccgcggccccggccgccgctccggct
ccgtctccggcgaagcccgccgccgctgccccggcagccccggcaccggccaaggccgcc
ccggccgcggctccggcgaagcccgcggcggccaagcccgccgccgcgcccgccaagccg
aaggccaaggcggacgaggccaccgaggccccggccggaccggagtacgtgacgctgcgc
ggcccctccgccgccgtcgcgaagaacatgaacgcctcgctggagctgccgacggccacg
tccgtccgcgcggtaccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccac
ctcaagcgcgcccgcggcgggaagatctccttcacccacctcatcgggtacgcgatggtc
caggccctcaaggccatgccgtcgatgaactactccttcgcggagaaggacggcaagccc
accctggtcaagccggaccacgtcaacctgggtctggccatcgacctggtgaagccgaac
ggcgaccgccagctcgtcgtcgcggccatcaagaaggccgagacgctcaacttcttcgag
ttctggcaggcgtacgaggacatcgtccggcgcgcccgcatcggcaagctcggcatggac
gacttcaccggcgtcaccgcctcgctgaccaaccccggcggcatcggcaccgtccactcg
gtgccccgcctgatgcccggacagggcctcatcatgggcgtcggcgcgatggactacccg
gcggagttccagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatg
acgctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctg
cggatcgtctcgcagctcctgctcggccagaacgagttctacgacgagatcttcaaggcc
ctgcgcatcccgtacgagccggtccgctggctcacggacatcgacgcgtcgcacgacaac
gacgtgacgaaggccgcgcgcgtcttcgagctgatccactcctaccgggtccgcggccac
gtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctcgacatc
accgagcacggcctcaccctgtgggacctggagcgggacttcgcggtcggcgggttcgcc
ggcaagtcgatgatgaagctccgcgacatcctcggcgtgctgcgcgagtcgtactgccgc
accaccggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggctccaggac
cgggtggagcggccccgtgcccagcagcccgagcgcgaggagcagctgcgcatcctgcgc
cggctgaacgcggccgaggcgttcgagaccttcctccagaccaagtacgtcggtcagaag
cgcttctcgctggagggcggcgagtccgtgatcccgctgctcgacgcggtcatcgactcc
gccgccgaggcccgcctcgacgaggtcgtcatcggcatggcccaccgcggccgcctcaac
gtgctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaat
ctcgacccgcgctcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggc
accttcaccggtctggacggcgagcagatcaaggtctcgctggccgccaacccctcgcac
ctggaggcggtcgacccggtcctggagggcatcgcccgcgccaagcaggacatcatcaac
aagggcggcacggacttcacggtcctgcccgtcgcgctccacggcgacgcggccttcgcg
ggccagggcgtcgtcgccgagacgctcaacatgtcgcagctgcgcggctaccgcaccggc
ggcaccgtgcacgtggtgatcaacaaccaggtcggcttcaccgccgccccggagtcctcg
cgctcctcgatgtacgccaccgacgtggcgcgcatgatcgaggcgccgatcatccacgtc
aacggcgacgacccggaggccgtggtccgtgtcgcgcggctcgccttcgagttccggcag
gcgttcaacaaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgag
ggcgacaacccggagttcaccaacccgcagatgtacacgctgatcgacaagaagcgctcg
gtgcgcaagctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggcc
gagcaggcgctccaggacttccagggccagctggagaaggtcttcgccgaggtccgcgag
gccacctcgcagcccgccgccccgcacgtcccggagccgcaggccgcgttcccggtggcc
gtggacacggcggtctccgccgaggtcatcaagcggatcgccgagtcccaggtcaacatc
cccgagtcgatcaccgtccacccccgtctgatgccgcagatgcagcgtcgcgcggcctcg
gtggagaacggcacgatcgactggggcatgggcgagaccctggccatcggttcgctgctg
atggagggcaccccggtccggctcgcaggccaggacagccgccgcggcaccttcggccag
cgccacgcggtcctggtggaccaggtcaccggcgaggactacaccccgctgctgtacctc
accgaggaccaggcccggtacaacgtctacgactcgctgctcagcgagtacgcggcgatg
ggcttcgagtacggctactcgctggcccgcccggagtcgctggtcatctgggaggcccag
ttcggtgacttcgtcaacggcgcgcagaccgtcgtggacgagttcatctcctcggccgag
cagaagtggggccagacctccggcgtcacgctgctgctgccgcacggctacgagggccag
ggcccggaccactcgtccgcccgcccggagcgcttcctccagatgtgcgcgcaggacaac
atgacggtcgcgatgccgaccctcccctcgaactacttccacctgctgcgctggcaggtg
cacaacccgcaccacaagccgctcatcgtcttcaccccgaagtcgatgctgcgtctgaag
gcggcggcgtcgaagatcgaggagttcaccagcggcggcttccgtccggtgatcggcgac
gacaccgtcaaggcggaggacgtccgcaaggtcgtcttcgtctcgggcaagctcttctac
gacctggacgccgagcgggagaagcgcggcgacacggagaccgcgctcatccggctggag
cggctgtacccgctgccgggtgcggagatccaggccgagatcgccaagtacccgaacgcc
gagaagtacctgtgggcccaggaggagccggccaaccagggtgcgtggccgttcatcgcg
ctcaacctgatcgaccacctggacctggccgtgggcgcggacgtgccgcacggcgagcgc
ctgcgccgcatctcgcggccgcacggctcgtccccggcggtcggctcggccaagcgccac
caggcggagcagacgcagctggtcaacgaggtcttcgaggcctga
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