Streptomyces chartreusis: CP983_34730
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Entry
CP983_34730 CDS
T07157
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
scha
Streptomyces chartreusis
Pathway
scha00270
Cysteine and methionine metabolism
scha00450
Selenocompound metabolism
scha00670
One carbon pool by folate
scha01100
Metabolic pathways
scha01110
Biosynthesis of secondary metabolites
scha01230
Biosynthesis of amino acids
scha04980
Cobalamin transport and metabolism
scha04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
scha00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CP983_34730 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
CP983_34730 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
CP983_34730 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
CP983_34730 (metH)
04980 Cobalamin transport and metabolism
CP983_34730 (metH)
Enzymes [BR:
scha01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
CP983_34730 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
QEV71293
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Position
7875845..7879363
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AA seq
1172 aa
AA seq
DB search
MASLPPTPSADSRTRVSALREALATRVVVADGAMGTMLQAQEPTLEDFQNLEGCNEILNV
TRPDIVRSVHEAYYDAGVDCVETNTFGANYAAAAEYDIADRVYELSEAGARIARETADAF
GARDGRQRWVLGSIGPGTKLPTLGHIGYTTIRDAFQQNAEGLIAGGADALIVETTQDLLQ
TKAAVIGAQRARELAGLDVPIIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGMNCAT
GPAEMSEHLRYLSRHSRIPLSCMPNAGLPVLGKNGATYPLTAPELADAHETFVRDYGLSL
IGGCCGTTPEHLRQLVERVQGVTPTVRDPRPEPGAASLYQTVPFRQDTSYLAIGERTNAN
GSKKFREAMLEARWDDCVEMAREQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTL
PIVLDSTEVPVIRAGLEKLGGRAVINSVNYEDGDGPESRFAKVTELAQEHGAALIALTID
EEGQARTPEKKVAIAQRLIEDLTGNWGIHESDILIDTLTFTICTGQEESRKDGIATIEAI
RELKRRHPDVQTTLGLSNISFGLNPAARILLNSVFLDECVKAGLDSAIVHASKILPIARF
SEEEVQTALDLIHDRRSEGYDPLQKLMQLFEGATAKSLKAGKAEELAALPLEERLKRRII
DGEKNGLEADLDAALQDRPALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKAAV
AYLEPHMEKTDADGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILE
AAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLAADYPVILGGAALTRAYVEQDLHEI
YEGEVRYARDAFEGLRLMDALIGVKRGVPGVQLPELKQRRVRTAATAAVVDERPEEGHVR
SDVATDNPVPEPPFWGTRVIKGIQLKEYASWLDEGALFKGQWGLKEVRSGEGPSYQELVE
TEGRPRLRGLLDKLQTENLLEAAVVYGYFPCVSKDDDLILLDEHGNERTRFTFPRQRRGR
RLCLADFFRPQESGETDVVGLQVVTVGNRIGEETARLFESNSYRDYLELHGLSVQLAEAL
AEYWHARVRSELGFAGEDPAEMEDMFALKYRGARFSLGYGACPNLEDRSKIADLLQPERI
GVHLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3519 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgttgccaccgaccccttccgccgacagccggacccgtgtgtccgcactccgt
gaggcgctcgccacccgagtggtggtggccgacggagcgatgggcaccatgttgcaggcc
caggaacccaccctggaggactttcagaacctcgagggctgcaacgaaatcctgaacgtc
acccgtccggacatcgtccgctccgtccacgaggcgtactacgacgccggcgtggactgc
gtggagaccaacaccttcggcgccaattacgccgcggcggccgagtacgacatcgccgac
cgggtgtacgaactgtccgaggccggcgcccgtatcgcccgcgagaccgccgacgcgttc
ggggcccgggacggccgccagcgctgggtcctcggctccatcgggccgggcaccaagctg
cccacgctcggccacatcggctacaccacgatccgcgacgccttccagcagaacgccgag
ggcctgatcgcgggcggcgccgacgccctgatcgtggagaccacccaggacctgctccag
accaaggccgccgtgatcggcgcccagcgcgcccgcgagctcgccggcctggacgtgccg
atcatcgtctccgtcaccgtcgagaccaccggcaccatgctgctgggctccgagatcggc
gccgcgctcaccgcgctggagccgctcggcatcgacatgatcggcatgaactgcgcgacc
ggccccgccgagatgagcgagcacctgcgctacctctcccggcactcccgcatcccgctg
tcgtgcatgccgaacgcgggcctgccggtcctcggcaagaacggcgccacctacccgctc
accgccccggaactcgccgacgcccacgagaccttcgtacgggactacggcctctccctg
atcggcggctgctgcggcaccacccccgagcacctgcgccagctcgtcgagcgcgtccag
ggcgtcaccccgaccgttcgcgacccgcgccccgaacccggcgccgcctccctctaccag
acggttccgttccgccaggacacctcctacctggccatcggcgagcgcaccaacgccaac
ggctcgaagaagttccgcgaggccatgctggaggcccgctgggacgactgcgtggagatg
gcgcgcgaacagatccgcgagggcgcgcacatgctcgacctgtgcgtggactacgtcggc
cgcgacggcgtcgccgacatggaggagctcgccggccgcttcgccaccgcctccaccctg
ccgatcgtcctggactccaccgaggtgccggtcatccgggccggcctggagaagctcggc
ggccgcgcggtcatcaactccgtgaactacgaggacggcgacggccccgagtcccgcttc
gcgaaggtcaccgagctcgcccaggagcacggcgccgccctgatcgcgctgaccatcgac
gaggagggccaggcccgcaccccggagaagaaggtcgcgatcgcccaacggctgatcgag
gacctgaccggcaactggggcatccacgagtcggacatcctcatcgacaccctgaccttc
accatctgtaccggtcaggaggagtcgcgcaaggacggcatcgccaccatcgaggcgatc
cgcgaactcaagcgccgccacccggacgtccagaccaccctcggtctgtccaacatctcc
ttcggcctcaacccggccgcccgcatcctgctgaactccgtcttcctcgacgagtgcgtc
aaggcgggcctggactcggcgatcgtgcacgcctcgaagatcctgccgatcgcccgcttc
agcgaggaagaggtccagacggccctcgacctcatccacgaccgccgcagcgagggctac
gaccccctccagaagctgatgcagctcttcgagggcgccaccgccaagtccctgaaggcg
ggcaaggccgaggaactggccgccctcccgctggaggaacgcctcaagcgccgcatcatc
gacggcgagaagaacggcctggaggccgacctggacgccgcgctccaggaccgccccgcc
ctcgacatcgtcaacgacaccctcctggacggcatgaaggtcgtcggcgaactcttcggc
tccggccagatgcagctgccgttcgtcctccagtccgccgaggtcatgaaggccgccgtc
gcttacctcgaaccgcacatggagaagaccgacgccgacggcaagggcaccatcgtgctg
gccaccgtgcgcggcgacgtgcacgacatcggcaagaacctcgtggacatcatcctgtcc
aacaacggctacaacgtggtcaacctgggcatcaagcagcccgtctccgcgatcctggag
gccgccgaggagcaccgggccgacgtcatcggcatgtccggcctgctggtgaagtccacg
gtgatcatgaaggagaacctggaggagctcaaccagcgcggcctggcggcggactacccc
gtcatcctcggcggcgccgccctgacccgtgcctacgtcgagcaggacctgcacgagatc
tacgagggcgaagtccgctacgcccgcgacgcgttcgagggcctgcgcctgatggacgcc
ctcatcggcgtcaagcgcggcgtgcccggcgtccagctgcccgagctcaagcaacgccgc
gtgcggaccgccgccacggcggccgtggtggacgagcggcccgaggagggccacgtccgc
tccgacgtcgccaccgacaacccggtccccgagccccccttctggggcacccgcgtcatc
aagggcatccagctcaaggagtacgcctcctggctcgacgagggcgccctgttcaagggg
cagtggggcctcaaggaggtccgcagcggcgagggaccgtcgtaccaggaactcgtcgag
accgagggtcgcccgcggctgcgcggtctgctcgacaagctccagacggagaacctcctc
gaagcggccgtcgtctacggctacttcccgtgcgtctccaaggacgacgacctgatcctg
ctcgacgagcacggcaacgagcgcacccgcttcaccttcccgcgccagcgccgcggccgc
cggctgtgcctcgcggacttcttccgtccgcaggagtccggcgagaccgacgtcgtgggc
ctccaggtcgtcaccgtgggcaaccgcatcggcgaggagaccgcccggctcttcgagtcg
aactcctaccgcgactacctcgaactgcacggcctgtccgtgcagttggccgaggcgctc
gccgagtactggcacgcgcgcgtgcgttcggaactcggcttcgccggtgaggacccggcc
gagatggaggacatgttcgcgctgaagtaccggggtgcccgcttctcgcttggctacggc
gcctgcccgaacctggaggaccggtccaagatcgccgacctgctccagccggagcgcatc
ggcgtccacctgtccgaggagttccagctgcaccccgagcagtccacggacgcgatcgtg
atccaccacccggaggcgaagtacttcaacgcacggtga
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