Streptomyces chengbuensis: QRN89_06385
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Entry
QRN89_06385 CDS
T10474
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sche Streptomyces chengbuensis
Pathway
sche00270
Cysteine and methionine metabolism
sche00450
Selenocompound metabolism
sche00670
One carbon pool by folate
sche01100
Metabolic pathways
sche01110
Biosynthesis of secondary metabolites
sche01230
Biosynthesis of amino acids
sche04980
Cobalamin transport and metabolism
sche04981
Folate transport and metabolism
Brite
Enzymes [BR:
sche01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
QRN89_06385 (metH)
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NCBI-ProteinID:
WJY49466
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Position
complement(1414149..1417700)
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AA seq
1183 aa
AA seq
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MASLPTPSADSPTSAGSGTSHDSRTRADALRRALATRVVVADGAMGTMLQAQDPTLDDFQ
DLEGCNEILNVTRPDIVRSVHSAYFEVGVDCVETNTFGANFAALGEYDIPERVFELSEAG
ARIAREVADEFTAATGRQRWVLGSMGPGTKLPTLGHAPYVTLRDAYQQNAEGMIAGGADA
LLVETTQDLLQTKAAILGARRAMEVAGLTVPLICSVTVETTGTMLLGSEIGAALTALEPL
GIDMIGLNCATGPAEMSEHLRYLARHSRVPLSCMPNAGLPVLGKDGAHYPLTAPELADAQ
ETFVREYGLSLVGGCCGTTPEHLRQVVERVRGLEPAERAPRPEPGAASLYQTVPFRQDTS
YLAIGERTNANGSKKFREAMLDARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEE
LAGRFATASTLPIVLDSTEVEVIRAGLEKLGGRAVINSVNYEDGDGPESRFAKVTELARE
HGAALIALTIDEEGQARTAEKKVEIAERLITDLTTNWGIHESDILIDTLTFTICTGQEES
RKDGIATIEAIRELKRRHPDVQTTLGLSNISFGLNPAARILLNSVFLDECVKAGLDSAIV
HASKILPIARFDEEQVTTALDLIHDRRSEGYDPLQKLMALFEGATAKSLKAGKAEELAAL
PLEERLKRRIVDGEKNGLEADLDAALADRPALDIVNDTLLDGMKVVGELFGSGQMQLPFV
LQSAEVMKSAVAYLEPHMEKSDAEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNL
GIKQPVSAILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRRLAADYPVILGGAALT
RAYVEQDLHEIYEGEVRYARDAFEGLRLMDALIAVKRGVPGAALPELKQRRVRSTATAVV
EERPEEQGAVRSDVAVDNPVPEPPFWGTRVVKGIQLKEYASWLDEGALFKGQWGLKQART
GDGPSYEELVETEGRPRLRGWLDQLHTQNLLEAAVVHGYFPCVSKGDDLIVLDEQGNERT
RFTFPRQRRGRRLCLADFFRPEESGETDVVGLQVVTVGSRIGEATAKLFASDSYRDYLEL
HGLSVQLAEALAEYWHARVRAELGFAGEDPAEIEDMFALKYRGARFSLGYGACPDLEDRA
KIAELLEPERIGVKLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3552 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgttgccgaccccttccgccgacagcccgacttccgcaggcagcggtacgtcc
cacgacagccggacccgagccgacgccctgcgccgcgcgctggccacccgtgtggtggtc
gccgacggtgcgatgggcacgatgctgcaggcgcaggaccccaccctcgacgacttccag
gatctcgagggctgcaacgagattctgaacgtgacccgcccggacatcgtccgttcggtc
cattcggcctacttcgaggtcggtgtggactgtgtggagacgaacacgttcggggcgaac
ttcgccgccctgggtgagtacgacatccccgagcgcgtcttcgagctgtcggaggcggga
gcgcgcatcgcgcgcgaggtggcggacgagttcaccgcggccacggggcggcagcggtgg
gtgctcgggtccatgggaccggggacgaagctgccgacgctcggccatgccccgtacgtc
acgctccgcgacgcctaccagcagaacgcggagggcatgatcgcgggcggcgcggacgcg
ctgctggtggagaccacacaggacctgctgcagacgaaggcggcgatcctgggtgcgcgc
agggcgatggaggtcgccggactcaccgtcccgttgatctgttcggtgacggtggagacg
acgggcacgatgctgctcggttcggagatcggcgcggcgctgacggcgctggagccgctc
ggcatcgacatgatcgggctgaactgcgcgaccgggccggcggagatgagtgaacacctg
cgctatctggcccgtcactcgcgcgtgcccctgtcctgcatgcccaacgcgggcctgccg
gtgctgggcaaggacggcgcgcactatccgctgaccgcaccggagctggcggacgcgcag
gagaccttcgtccgcgagtacgggctgtcgttggtgggcggctgctgcgggacgacgccg
gagcatctgcggcaggtcgtggagcgggtccgcggcctggagccggccgagcgcgccccg
cgtcccgagcccggtgccgcgtcgctgtaccagacggtgccgttccgccaggacacctcg
tacctggcgatcggggagcggacgaacgccaacgggtcgaagaagttccgcgaggccatg
ctggacgcccgctgggacgactgcgtggagatggcccgggaccagatccgcgagggtgcc
cacatgctcgacctgtgcgtcgactacgtcggccgggacggcgtggcggacatggaggag
ctggcgggccggttcgcgacggcctcgacgctgccgatcgtgctcgactccaccgaggtg
gaggtgatccgtgccggtctggagaagctgggtggccgggcggtgatcaactcggtgaac
tacgaggacggcgacggtcccgagtcgcggttcgcgaaggtcacggagctggcccgggag
cacggagcggcgctgatcgcgctcaccatcgacgaggagggccaggcccgcaccgccgag
aagaaggtcgagatcgccgagcggctcatcaccgacctcaccaccaactggggcatccac
gagtccgacatcctcatcgacaccctcaccttcacgatctgcacgggccaggaggagtcc
cgcaaggacggcatcgccaccatcgaggcgatccgcgagctgaagcggcgccacccggac
gtgcagacgacgctcggcctgtcgaacatctccttcgggctcaaccccgccgcgcggatc
ctcctcaactccgtcttcctcgacgagtgcgtcaaggccgggctggactcggcgatcgtg
cacgcctcgaagatcctgccgatcgcccgcttcgacgaggagcaggtcaccacggcgctg
gacctgatccacgaccggcgttccgagggctacgacccgctgcagaagctgatggccctg
ttcgagggcgccaccgccaagtccctgaaggccggcaaggccgaggagctggccgccctc
cccctggaggagcgtctcaagcggcgcatcgtcgacggcgagaagaacgggctggaggcc
gacctcgacgctgccctcgcggaccgcccggcgctcgacatcgtcaacgacaccctgctg
gacggcatgaaggtcgtcggcgaactgttcggctccggccagatgcagctgccgttcgtg
ctgcagtcggccgaggtgatgaagtcggcggtggcctatctggaaccgcacatggagaag
tccgacgcggaagggaagggcacgatcgtgctcgccaccgtccgcggcgacgtccacgac
atcggcaagaacctcgtggacatcatcctgtccaacaacggctacaacgtcgtcaacctc
gggatcaagcagcccgtctccgcgatcctggaggccgccgaggagcaccgggccgatgtg
atcggcatgtccgggctcctggtgaagtccaccgtgatcatgaaggagaacctggaggag
ctcaaccagcgcaggctcgccgccgactaccccgtcatcctcggcggagccgccctcacc
cgcgcctacgtcgaacaggacctccacgagatctacgagggcgaagtccgctacgcccgc
gacgccttcgagggcctccgcctcatggacgccctgatcgcggtcaagcgcggtgtcccc
ggcgccgcgctccccgagctgaagcagcgccgggtacggagcaccgccaccgcggtcgtc
gaggagcggccggaggaacagggtgccgtgcgctccgacgtcgccgtcgacaacccggtg
ccggagcccccgttctgggggacgagggtcgtcaagggcatccagctcaaggagtacgcc
tcctggctggacgagggtgcgctcttcaagggccagtggggactgaagcaggcccgcacc
ggcgacggaccgtcctacgaggagctggtggagaccgagggccgcccgcggctgcggggc
tggctcgaccagctccacacgcagaacctgctcgaggccgccgtcgtccacggctacttc
ccctgcgtctccaagggcgacgacctgatcgtcctcgacgagcagggcaacgagcgcacc
cgcttcaccttcccccggcagcgccgcggccgccggctgtgcctggccgacttcttccgc
ccggaggagtcgggcgagaccgacgtcgtcggcctccaggtggtcaccgtcggctcgagg
atcggcgaggccacggccaagctgttcgcctccgactcctaccgcgactacctcgagctc
cacggcctgtccgtccagctcgccgaggccctcgccgagtactggcacgcgcgggtccgc
gccgagctcgggttcgccggcgaggacccggcggagatcgaggacatgttcgccctgaag
taccgcggcgcccggttctccctcggctacggagcctgccccgacctcgaggaccgtgcc
aagatcgccgagctgctggagcccgagcggatcggcgtcaagctctcggaggagttccag
ctccaccccgagcagtccaccgacgccatcgtgatccatcacccggaggcgaagtacttc
aacgcgcggtga
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