Streptomyces chengbuensis: QRN89_23345
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Entry
QRN89_23345 CDS
T10474
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sche Streptomyces chengbuensis
Pathway
sche00020
Citrate cycle (TCA cycle)
sche00630
Glyoxylate and dicarboxylate metabolism
sche00785
Lipoic acid metabolism
sche01100
Metabolic pathways
sche01110
Biosynthesis of secondary metabolites
sche01120
Microbial metabolism in diverse environments
sche01200
Carbon metabolism
sche01210
2-Oxocarboxylic acid metabolism
Module
sche_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sche_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sche00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
QRN89_23345
00630 Glyoxylate and dicarboxylate metabolism
QRN89_23345
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
QRN89_23345
Enzymes [BR:
sche01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
QRN89_23345
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
QRN89_23345
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
QRN89_23345
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
QRN89_23345
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WJY52483
LinkDB
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Position
complement(5251185..5254988)
Genome browser
AA seq
1267 aa
AA seq
DB search
MSSQSPSNSSTSTDPDGQGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGGAAGEAAPTPSAATATETPGTAQAPAPAAPAAQAPAAPAQAPAAPAQPAASAPAPAKP
AAPAKPAAAAPAKPAAKAAPAAGTPDGPEMLPLRGPSAAVAKNMNASLELPTATSVRAVP
VKLLFDNRIVINNHLKRARGGKISFTHIIGYAMVQAIKAMPSMNWSYGEKDGKPVLVKPP
HVNLGLAIDLVKPNGDRQLVVAAIKKAETMNFFEFWQAYEDIVRRARSNKLTMDDFTGVT
VSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTY
DHRVIQGAASGEFLRIVANLLLGEDGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTKAA
RVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFGGKSMMK
LRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHAKPEREEQLRILRRLNAAEA
FETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVG
KSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPV
LEGVVRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVI
NNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEACVRVARLAFEFRQTFNKDVV
IDLICYRRRGHNEGDNPQFTNPQMVNLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDF
QGQLEKVFAEVREATSHPAPAHVPDAQAEFPVSVTTGISQEVVKRIAESQVNIPDNITVH
PRLLPQLQRRAASVEDGTIDWGMGETLAIGSLLMEGTPVRLAGQDTRRGTFGQRHAVLVD
QETNEDYTPLLYLAEDQARYNVYDSLLSEYAAMGFEYGYSLARPESLVMWEAQFGDFVNG
AQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPT
LPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKVEEFTTGGFRPVIGDDSVNAAD
VRKVVFCSGKVYYDLEAERQKRGATDTAIIRLERLYPLPGAELQAEIAKFPNTEKYLWVQ
EEPANQGAWPFIALNLIDHLDLAVGADIPHGERLRRISRPHSSSPAVGSAKRHQAEQQQL
VNEVFEA
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagtacttcgaccgaccccgacgggcaggggaag
aaccccgctgccgcgttcggggccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaattcggtcgaccgcgcctggtgggacttcttcgccgactacaagccg
ggcggcggggccgccggcgaggccgcgccgacgccgtcggccgcgacggccacggagacg
ccgggcaccgcacaggctccggctcccgcggcccccgcggcgcaggctcccgcagccccg
gcccaggcgccggccgcccccgcgcagcccgccgcctcggccccggcccccgcgaagccc
gccgcccccgcgaagcccgccgccgctgctccggcgaagcccgccgccaaggccgcaccg
gctgccgggactcccgacggccccgagatgctgccgctgcgcggcccctccgccgcggtc
gcgaagaacatgaacgcctcgctggagctgccgacggccacgtccgtccgcgccgtcccg
gtgaagctgctcttcgacaaccggatcgtcatcaacaaccacctgaagcgcgcccggggc
gggaagatctccttcacgcacatcatcgggtacgcgatggtgcaggcgatcaaggccatg
ccgtcgatgaactggtcgtacggcgagaaggacggcaagccggtcctggtcaagcccccg
cacgtgaacctcggcctcgccatcgacctggtgaagccgaacggcgaccggcagctcgtg
gtcgcggccatcaagaaggccgagaccatgaacttcttcgagttctggcaggcctacgag
gacatcgtccgccgcgcccgcagcaacaagctgacgatggacgacttcaccggcgtcacc
gtctcgctgaccaaccccggcggtctcggcaccgtccactccgtgccgcggctgatgccc
ggacagtcggtgatcatgggtgtcggctcgatggactacccggcggagttccagggcacg
tcccaggacaccctgaacaagctgggcatctccaaggtcatgaccctgacctcgacgtac
gaccaccgggtcatccagggtgccgcctccggcgagttcctgcggatcgtcgccaacctc
ctcctcggcgaggacggcttctacgacgacatcttcgaggcgctgcgcatcccctacgag
ccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcc
cgggtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgac
ccgctggagtaccgccagcgcaagcacccggacctggacatcaccgagcacgggctcacc
ctgtgggacctggagcgcgagttcgcggtcggcggcttcggcggcaagtcgatgatgaag
ctgcgcgacatcctcggcgtcctgcgcgactcgtactgccgcaccaccggcatcgagttc
atgcacatccaggacccgaagcagcgcaagtggatccaggaccgcgtggagcgcccgcac
gccaagccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgcggcggaggcc
ttcgagaccttcctgcagaccaagtacgtcggccagaagcgcttctcgctggagggcggc
gagtccgtcatcccgctgctcgacgcggtcatcgactcggccgccgagtcccgcctcgac
gaggtcgtcatcggcatggcccaccgcggccggctgaacgtcctggcgaacatcgtgggc
aagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcac
ggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggactcgacggc
gagcagatcaaggtgtcgctggtcgccaacccgtcgcacctggaggcggtcgacccggtc
ctcgagggcgtcgtccgcgccaagcaggacatcatcaacaagggcggcacggacttcacc
gtcctgccggtcgccctgcacggtgacgcggcgttcgccggccagggtgtcgtcgccgag
accctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtcatc
aacaaccaggtcggcttcaccgccgccccggagtcgtcgcgttcgtcgatgtacgcgacc
gacgtggcgcgcatgatcgaggcgccgatcttccacgtcaacggcgacgacccggaggcg
tgcgtccgagtggcgcggctcgccttcgagttccgccagacgttcaacaaggacgtcgtg
atcgacctcatctgctaccgccgccgcggtcacaacgagggcgacaacccgcagttcacc
aacccgcagatggtgaacctgatcgacaagaagcgctcggtccgcaagctctacaccgag
tcgctcatcggtcgcggcgacatcacgctggaagaggccgagcaggccctgcaggacttc
cagggccagctggagaaggtcttcgcggaggtccgcgaggccaccagccacccggccccg
gcccatgtcccggacgcccaggccgagttcccggtgtccgtcaccacggggatctcccag
gaggtcgtcaagcggatcgccgagtcccaggtcaacatccccgacaacatcaccgtccac
ccgcgactgctgccgcagctgcagcgccgcgcggcctcggtcgaggacggcacgatcgac
tggggcatgggcgagaccctcgccatcggctcgctgctcatggagggcaccccggtccgg
ctcgccggccaggacacccgccggggcaccttcggccagcgccacgcggtgctggtggac
caggagaccaacgaggactacaccccgctgctctacctggccgaggaccaggcccgctac
aacgtctacgactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcg
ctggcccgcccggagtcgctggtcatgtgggaggcccagttcggcgacttcgtcaacggc
gcccagaccgtcgtcgacgagttcatctcctcggccgagcagaagtggggccagacctcc
ggcgtcacgctgctcctgccgcacggctacgagggccagggcccggaccactcgtccgcc
cggccggagcgcttcctccagctgtgcgcgcagaacaacatgacggtcgccatgccgacg
ctgccgtcgaactacttccacctgctgcgctggcaggtccacaacccgcatcacaagccg
ctcatcgtcttcaccccgaagtcgatgctgcgtctgaaggcagcggcgtccaaggtggag
gagttcacgaccggcggcttccgcccggtcatcggcgacgactcggtgaacgccgccgac
gtccgcaaggtcgtcttctgctccggcaaggtctactacgacctggaggccgagcggcag
aagcgcggtgccacggacacggcgatcatccgcctggagcgcctgtacccgctgccgggt
gcggaactgcaggccgagatcgccaagttcccgaacaccgagaagtacctgtgggtccag
gaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccacctg
gacctggcggtcggcgcggacatcccgcacggcgagcgcctgcgccgcatctcccgcccc
cactcgtcgtccccggccgtgggctcggcgaagcggcaccaggcggagcagcagcagctg
gtgaacgaggtcttcgaggcctga
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