Streptomyces chromofuscus: IPT68_00680
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Entry
IPT68_00680 CDS
T07378
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
schf
Streptomyces chromofuscus
Pathway
schf00010
Glycolysis / Gluconeogenesis
schf00020
Citrate cycle (TCA cycle)
schf00620
Pyruvate metabolism
schf00785
Lipoic acid metabolism
schf01100
Metabolic pathways
schf01110
Biosynthesis of secondary metabolites
schf01120
Microbial metabolism in diverse environments
schf01200
Carbon metabolism
schf01210
2-Oxocarboxylic acid metabolism
Module
schf_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
schf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
IPT68_00680 (aceE)
00020 Citrate cycle (TCA cycle)
IPT68_00680 (aceE)
00620 Pyruvate metabolism
IPT68_00680 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IPT68_00680 (aceE)
Enzymes [BR:
schf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
IPT68_00680 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
QOV44599
UniProt:
A0A7M2T8Z4
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Position
175710..178391
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AA seq
893 aa
AA seq
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MTEDTLGRPSEPGQSPDLDPEETAEWAASVDAVAAAAGPHRASYLMRRTLEHAERVGLVL
PKLLESDYVNSIPTAAEPSFPGDEEMERRITAWNRWNAAAMVTRGSRYGLGGHIATFASA
AWLYETGFNHFFRGKDADGSGDQLFLQGHASPGIYARAFLDGRLTEEQLDRFRQETGRGG
LPSYPHPRRLPWLWEFPTVSMGLGPLTAIHQARFNRYLRHRGIKDTSLSHVWAFLGDGEM
DEPESTAALALAGREGLDNLTFVVNCNLQRLDGPVRANFKIVQELEAQFRAAGWHVVKAL
WGTAWDDLLTLDTTGALVRRLREVPDGQFQTYATRDAAYIRQHFFGADPDLVEMARVLTD
AQIIDCFHTSRAGHEPRKVHAAYRAAVEHRGAPTVVLAQTVKGHTLGSGFESRNANHQMK
KLTGREFRALRDLLDLPIPDSRLDGDLVPYVHPGTDSAEVRYLHERRAALGGPAPARRFH
PVALPSPSARHFQALAQGSGTQEIATTTALVRLLKDLMREADTGRRWVPIVPDEARTFGM
ESFFPAFGIYSPVGQNYEPVDRDQLLYYREAQDGQVLNEGITEAGSMASFTAAATSYATH
GEPMIPFYIFYAMFGWQRTADQMWALADQLGRGFLVGATAGRTTMTGEGLQHGDGHSHLI
ASTNPAAVAYDPAFAYEIAVIVREGLRRMYGPDAEDVFYYLTVYNEPRIQPAMPLEPGVE
EGILKGLYRFRQAESHHPSANVPRLQLLASGTAIHWVLEAQRLLAEDWGVAADVWSATSW
SELRRDALECDAARLRGEERVPYVTRALAGAPGPVLAVSDWMRTVPDQISQWVPQEWHSI
GTDGFGLSGTREDVRRHFGVDAQSIVVAALSALAQTGQVKPDAVREARARYGR
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaggacacacttggccggccgagcgaaccgggtcagagtcccgacctcgacccc
gaggagaccgccgagtgggcggcgtccgtcgacgccgtcgccgcagccgccgggccacac
cgcgcctcgtacctcatgcggcgcaccctcgagcacgccgagcgtgtcggcctggtcctg
ccgaagcttctggaaagcgattacgtcaacagcattcccacggcagctgagccgtccttt
cccggcgacgaggagatggagcggcgcatcaccgcgtggaaccgctggaacgcggccgcg
atggtgacccgtggaagtcgctacgggctcggtggccacatagccaccttcgcctccgcc
gcgtggctctacgaaaccggcttcaaccacttcttccggggcaaggacgcggacggttcg
ggcgaccagctcttcctccaggggcacgcctcccccggcatctatgcgcgcgccttcctc
gacggcagactcaccgaggagcagctggaccgcttccggcaggagacgggacgcggaggc
ctgccgtcctacccgcacccgcgccggctcccctggttgtgggagttcccgacggtttcg
atgggcctgggcccgctcaccgcgatccaccaggcacgcttcaaccgctacctgcgccac
cgcggcatcaaggacacctccctttcgcacgtgtgggcgttcctcggcgacggcgagatg
gacgaacccgagtcgaccgctgccctggctctcgcgggccgcgaaggactggacaacctc
accttcgtcgtcaactgcaaccttcagcgactcgacggaccggtgcgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgtgcggcgggctggcacgtcgtgaaggcgctg
tggggcaccgcctgggacgatctgctcactctggacaccacgggcgccctcgtacggcgc
ctgcgcgaggttcccgacgggcagttccagacgtacgcgacgcgggacgcggcgtacatc
cgtcagcacttcttcggcgcggatccagacctggtcgagatggcgagggtgctgaccgat
gcgcagatcatcgactgcttccacacctcgcgggccgggcacgaaccacgcaaggtccac
gccgcgtaccgtgcggccgtcgaacaccggggcgcgccgacggtggtgctcgcccagacg
gtcaagggccacacgcttggcagcggattcgagtcacgcaacgccaatcaccagatgaag
aagctgacgggcagggaattccgcgcgctgcgagacctgctcgacctgccgatcccggac
agcaggctggacggcgacctggtcccgtacgtccacccgggcaccgactctgccgaggtc
cgctacctccacgagcgccgggcggcactgggtggtcccgctccggcacgcaggttccac
cccgtggcactgccctccccctcggccagacacttccaggcgctggcccagggatcgggg
acccaggagatcgcgaccaccacggcactcgtccgtctgctcaaggacctgatgcgggag
gcagacaccggcaggcgatgggtgccgatcgtgccggacgaggcccgcaccttcggcatg
gagtccttctttcccgccttcggtatttactccccggtcgggcagaactacgagccggtc
gaccgtgaccaattgctctactacagggaggctcaggacggccaagttctcaacgagggc
attaccgaggccggttccatggcctccttcacggccgccgccacctcgtacgcgacacac
ggcgaaccgatgatccccttctacatcttctatgcgatgttcggctggcagcgcacagcc
gaccagatgtgggcgctggccgaccaactcggccgcggcttcctcgtcggggccaccgcc
ggccgcaccaccatgaccggcgaaggccttcagcacggtgacggtcattcccacctgatc
gcctccaccaacccggcagcggtcgcctatgaccccgccttcgcttacgagatcgccgtc
atcgtccgcgagggactacgccgcatgtacggcccggacgcggaggacgtgttctactac
ctcaccgtctacaacgagcccaggatccagccggccatgccgttggagcccggcgtggag
gagggcatcctcaagggtctgtaccgcttccggcaggccgagagccaccacccgtcggcg
aacgtcccgcgcctgcaactccttgcctccggaaccgccattcactgggtgctggaagcg
cagcggttgctcgccgaggactggggcgtggccgccgacgtgtggtccgccacttcctgg
agcgagctgcggcgcgacgcactggagtgtgacgcggcacggctgcggggagaggagcgg
gtgccatacgtcacgcgtgcgctggccggagcgccgggacccgtgctggcggtcagcgac
tggatgcgaacggtcccggaccagatcagccagtgggtgccccaggagtggcattcgatc
ggcacggacgggttcggcctgtccggcacccgggaggacgtacgccgccacttcggggtc
gacgcccagtcgatcgtcgtcgcggcgctctccgccctcgcccagaccggccaggtcaag
ccggacgcggtgcgagaggcccgagcacggtacggccggtga
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