Streptomyces changanensis: NRO40_07535
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Entry
NRO40_07535 CDS
T09753
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
schg
Streptomyces changanensis
Pathway
schg00010
Glycolysis / Gluconeogenesis
schg00020
Citrate cycle (TCA cycle)
schg00620
Pyruvate metabolism
schg00785
Lipoic acid metabolism
schg01100
Metabolic pathways
schg01110
Biosynthesis of secondary metabolites
schg01120
Microbial metabolism in diverse environments
schg01200
Carbon metabolism
schg01210
2-Oxocarboxylic acid metabolism
Module
schg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
schg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NRO40_07535 (aceE)
00020 Citrate cycle (TCA cycle)
NRO40_07535 (aceE)
00620 Pyruvate metabolism
NRO40_07535 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NRO40_07535 (aceE)
Enzymes [BR:
schg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NRO40_07535 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
UUS30699
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Position
1712142..1714835
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AA seq
897 aa
AA seq
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MTDPTRIQPSELDQLPDRDPEETAEWQASLDAVTAAAGPHRAAYLMRRTLERAEGAGLAL
PKLLETDYVNTIPTSAEAGYGFDGDEEMEARITAWNRWNAAAMVTRGAKYGVGGHIATFA
SAAWLYETGFNHFFHGKERDGSGDQLFIQGHASPGIYARAFLDGRLTEAQLDNFRQESGG
NGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDVSASHVWAFLGDG
EMDEPESTAALALAAREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVK
SLWGTAWDELFRLDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALVEMAKLL
SDDKIVECFHTSRGGHEARKVFAAYKAALGHRGAPTVILAQTVKGHTLGRGFASKNANHQ
MKKLSVDEFKDMRDLLGLPIPDSAFADGQVPYGHPGADAPEVRYLQERRAALGGPAPARR
VHPVAPLPAPAEKVFTAFDKGSGSQSVATTMAFVRLVKDLVRDKETGRRWVPIVPDEART
FGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAVNGQILNEGITEAGSMADFIAASTAY
STHGEPMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHS
PVIAATNPAALSYDPAFAYEVAVIVKDGLRRMYGEGAPGEDPNVFYYLTVYNEPMPQPAK
PAVEGIDEAIVKGLYRFREGSGAEDAPRIQLLSSGTAIHWALQAQQTLAADWGVTADVWS
ATSWTELRRDALEADAALLRGEERVPYVRQALADARGPVLAVSDYMRQVPDQIAQWVEQD
YSSLGADGFGLSDTREAARRHFGVDAPSIVVAALAQLAKRGEVPASAVKDARERYGL
NT seq
2694 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacccgacccgcatccagccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgagtggcaggcgtccctcgacgccgtgaccgccgcggcggggccgcac
cgcgccgcgtacctgatgcgccgcaccctggagcgggcggagggcgccggtctggcgctg
ccgaagctgctggagaccgactacgtcaacaccatccccacctccgccgaggccggctac
ggcttcgacggcgacgaggagatggaagcccgcatcaccgcctggaaccggtggaacgcc
gccgccatggtgacccgcggcgcgaagtacggcgtcggcggtcacatcgccaccttcgcg
tcggccgcgtggctctacgagaccggcttcaaccacttcttccacggcaaggagcgggac
ggctccggcgaccagctgttcatccagggccacgcctcccccggcatctacgcccgcgcc
ttcctcgacggacggctcaccgaggcgcagctggacaacttccgtcaggagtccggcggc
aacggcctgccctcctacccgcacccgcggcgcctgccgtggctgtgggagttccccacg
gtctccatgggcctgggccccctctccgcgatctaccaggcgcggttcaaccgctacctc
accaaccgcggcatcaaggacgtctccgcctcgcacgtgtgggccttcctcggcgacggc
gagatggacgagccggagtcgaccgccgcactcgcgctcgccgcgcgtgagggcctcgac
aacctcaccttcgtcatcaactgcaacctgcagcgcctcgacggccccgtccgtgccaac
ttcaagatcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtgaag
tcgctgtggggcaccgcgtgggacgagctgttccggctcgacaccaccggcgcgctcgtc
cgccgcctccgcgaggtgccggacgcgcaggtgcagacgtaccagacccgtgacgccgcc
tacatccgcgaggacttcttcggcaaggacccggcgctcgtcgagatggcgaagctgctg
tccgacgacaagatcgtcgagtgcttccacacctcgcgcggcggccacgaggcccgcaag
gtcttcgccgcgtacaaggccgcgctcggccaccggggcgcgccgacggtgatcctcgcc
cagacggtgaagggccacaccctcggccgcggcttcgcctccaagaacgccaaccaccag
atgaagaagctctcggtggacgagttcaaggacatgcgcgacctgctcggcctgcccatc
ccggacagcgccttcgccgacggccaggtgccctacggccacccgggcgccgacgccccc
gaggtccgctacctccaggagcgccgcgccgccctcggcggccccgccccggcccgccgc
gtccaccccgtcgcgccgctgccggccccggcggagaaggtgttcaccgccttcgacaag
ggctccggctcccagtcggtcgccacgacgatggcgttcgtccggctggtgaaggacctg
gtccgcgacaaggagaccggccgccgctgggtcccgatcgtcccggacgaggcccgcacg
ttcggcatggagtcgctcttcccctcgctcggcatctactcgccgaagggccagacgtac
gagccggtcgaccgcgaccagctgatgtactacaaggaggccgtcaacggccagatcctg
aacgagggcatcaccgaggccggctcgatggccgacttcatcgccgcgtcgaccgcgtac
tcgacgcacggcgagccgatgatccccttctacatcttctactcgatgttcggctggcag
cggaccgccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggc
gccacggccggccgcaccacgctgaccggtgagggcctccagcacgccgacggccactcc
cccgtcatcgcggcgaccaacccggcggcgctcagctacgacccggcgttcgcctacgag
gtcgccgtgatcgtcaaggacggtctgcgccggatgtacggcgagggcgccccgggcgag
gacccgaacgtcttctactacctgaccgtgtacaacgagccgatgccgcagcccgccaag
ccggccgtcgagggcatcgacgaggccatcgtcaagggcctgtaccggttccgcgagggc
tcgggcgccgaggacgcgccgcgcatccagctgctgtcctccggcacggcgatccactgg
gcgctccaggcccagcagacgctggccgccgactggggcgtgaccgccgacgtgtggtcc
gcgacctcctggacggagctgcggcgcgacgcgctggaggccgacgcggccctgctgcgc
ggcgaggagcgggtgccgtacgtgcgccaggcgctggccgacgcccggggcccggtcctg
gcggtcagcgactacatgcgccaggtaccggaccagatcgcgcagtgggtcgagcaggac
tacagctcgctcggcgccgacggcttcggcctgtcggacacccgtgaggccgcccgccgc
cacttcggcgtggacgccccctcgatcgtggtcgccgccctggcccagctcgccaagcgc
ggcgaggtcccggcctccgcggtgaaggacgcccgggagcgctacggcctgtag
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