Streptomyces collinus: B446_11440
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Entry
B446_11440 CDS
T02787
Name
(GenBank) 2-oxoacid dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sci
Streptomyces collinus
Pathway
sci00010
Glycolysis / Gluconeogenesis
sci00020
Citrate cycle (TCA cycle)
sci00620
Pyruvate metabolism
sci00785
Lipoic acid metabolism
sci01100
Metabolic pathways
sci01110
Biosynthesis of secondary metabolites
sci01120
Microbial metabolism in diverse environments
sci01200
Carbon metabolism
sci01210
2-Oxocarboxylic acid metabolism
Module
sci_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sci00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
B446_11440
00020 Citrate cycle (TCA cycle)
B446_11440
00620 Pyruvate metabolism
B446_11440
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
B446_11440
Enzymes [BR:
sci01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
B446_11440
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AGS69110
UniProt:
S5VL07
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Position
2658143..2660845
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AA seq
900 aa
AA seq
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MTDPNAIQPSALDQLPDRDPEETAEWQASLDAVAREAGPHRAAYLMRRTLERAEAGGIAL
PKLLETDYVNTIPTSAEPGLPGDPEMEARITAWNRWNAAAMVTRGAKHGVGGHIATFASA
AWLYETGFNHFFKGKEGDGSGDQLYIQGHASPGIYARAFLDGRLNEAHLDNFRQEAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTSRGIKDVSASHVWAFLGDGEM
DEPESTAAIALAAREELDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKTL
WGTAWDELFQLDTTGALVRRLREVPDAQVQTYQTRSAAYIREDFFGKDPALAEMAKLLSD
DKILECFHLSRGGHEARKVYAAYKAAVEHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLSVDEFKAMRDLLGLPIKDSDFTDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRTH
ALAPLPAPAEKAFASFDKGSGSQNVATTMAFVRLVKDLVRDKETGRRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTAYAT
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALSYDPAFAYEIAVIVREGLRRMYGEAKPGEDQNVFYYLTVYNEPMPQPAKPQ
GLGIDEGIVKGLYRFNTAESAGVTVPANAPRIQLLGSGTAIHWTLEAQRMLADEWGVAAD
VWSATSWTELRRDALEADAALLRGEERLPYVRQALTGAEGPVLAVSDYMRQVPDQIAQWV
EQEWSSLGADGFGLSDTREAARRHFGVDAPSIVVAALAQLAKRGEVKATAVKEAREKYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgcgctcgaccagctcccggaccgcgacccg
gaggagaccgccgaatggcaggcctccctggacgccgtcgcgcgggaggccgggccgcac
cgcgccgcgtacctgatgcggcgcacgctggaacgcgccgaggcgggcggcatcgcgctg
ccgaagctcctcgagaccgactacgtcaacaccatccccacctccgcggagccgggcctg
cccggtgacccggagatggaggcccggatcaccgcctggaaccgctggaacgcggccgcc
atggtgacccgcggtgccaagcacggcgtcggcggccacatcgccaccttcgcctccgcc
gcctggctgtacgagaccggcttcaaccacttcttcaagggcaaggagggcgacggctcc
ggcgaccagctgtacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccgcctgaacgaggcgcacctggacaacttccgccaggaggccggcggcaacggc
ctgccgtcgtacccgcacccgcgccggctgccctggctctgggagttcccgaccgtctcc
atgggcctcggcccgctgtcggcgatctaccaggcgcgcttcaaccgctacctcaccagc
cgcggcatcaaggacgtctccgcctcgcacgtgtgggccttcctcggcgacggcgagatg
gacgagccggagtcgacggcggccatcgcactggccgcgcgtgaggaactggacaacctc
acgttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtcaagacgctg
tggggcaccgcctgggacgagctgttccagctcgacaccaccggcgcgctcgtacgccgg
ctgcgcgaggtaccggacgcccaggtccagacgtaccagacgcgcagcgccgcctacatc
cgcgaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctgctgagcgac
gacaagatcctcgagtgcttccacctctcgcgcggcggtcacgaggcccgcaaggtctac
gccgcgtacaaggccgccgtcgagcacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctctcggtggacgagttcaaggcgatgcgcgacctgctcggcctgccgatcaaggac
agcgacttcaccgacggcgtggtgccctacggtcacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgcggccctcggcggcccggccccggcccgccgcacccac
gcgctggccccgctgcccgcccccgcggagaaggcgttcgcctccttcgacaagggctcc
ggctcgcagaacgtggccaccaccatggccttcgtccgtctggtcaaggacctggtccgc
gacaaggagacgggcaggcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagagcctcttcccgtccctgggcatctactcccccaagggccagacgtacgagccg
gtcgaccgcgaccagctcatgtactacaaggaggccaagaacggccagatcctcaacgag
gggatcaccgaggccggttccatggccgacttcatcgccgcgtccaccgcgtacgcgacg
cacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggcgcgacg
gccggccgcacgaccctgacgggcgagggcctccagcacgccgacggccactccccggtg
atcgcggccaccaacccggcggcgctgtcgtacgaccccgcgttcgcctacgagatcgcg
gtgatcgtccgcgagggtctgcgccggatgtacggcgaggccaagccgggcgaggaccag
aacgtcttctactacctgacggtctacaacgagccgatgccgcagcccgcgaagccgcag
ggcctcggcatcgacgagggcatcgtcaaggggctgtaccgcttcaacacggcggagtcc
gcgggcgtgaccgtcccggccaacgccccgcgcatccagttgctgggctccggcacggcg
atccactggacccttgaggcgcagcgcatgctcgccgacgagtggggcgtggccgccgac
gtctggtccgccacctcgtggacggagctgcgccgcgacgcgctcgaggccgacgcggcc
ctgctgcgcggcgaggagcggctgccgtacgtccgccaggccctgaccggtgccgagggc
ccggtcctcgcggtctccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggagtggtcgtcgctgggcgccgacggcttcggtctgtcggacacccgtgaggcc
gcccgccgccacttcggcgtcgacgccccgtcgatcgtcgtcgcggccctggcccagctc
gccaagcgcggcgaggtcaaggcgacggcggtgaaggaagcccgggagaagtacgggctg
tag
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