Streptomyces collinus: B446_12400
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Entry
B446_12400 CDS
T02787
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sci
Streptomyces collinus
Pathway
sci00010
Glycolysis / Gluconeogenesis
sci00020
Citrate cycle (TCA cycle)
sci00620
Pyruvate metabolism
sci00785
Lipoic acid metabolism
sci01100
Metabolic pathways
sci01110
Biosynthesis of secondary metabolites
sci01120
Microbial metabolism in diverse environments
sci01200
Carbon metabolism
sci01210
2-Oxocarboxylic acid metabolism
Module
sci_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sci00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
B446_12400 (aceE)
00020 Citrate cycle (TCA cycle)
B446_12400 (aceE)
00620 Pyruvate metabolism
B446_12400 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
B446_12400 (aceE)
Enzymes [BR:
sci01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
B446_12400 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AGS69302
UniProt:
S5VFH5
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All DBs
Position
2865179..2867815
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AA seq
878 aa
AA seq
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MDERGRERARYLMLRLIERAREKRVAVPEMRSTDYVNTIPTKSEPFFPGNEEIERKILNA
TRWNAAVMVSRAQRPGIGVGGHIATFASSASLYDVGFNHFFRGKDDGKGGDQVFFQGHAS
PGIYARAFLLDRLSAEQLDGFRQEKSKYPNGLSSYPHPRSMPDFWEFPTVSMGLGPLGAI
FQARMNRYMEARGIADTSDSHVWAFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQ
RLDGPVRGNGKIIQELESVFRGAGWNVIKLIWDRTWDPLLAQDRDGVLVNRMNTTPDGQF
QTYATESGSYIREHFFGDDLRLRAMVENMTDDQILHLGRGGHDHRKIYAAFKAAKEHKGQ
PTVILAKTVKGWTLGPNFEGRNATHQMKKLTVDDLKRFRDRLHLPISDKELESGAPPYYH
PGRETEEIQYMHDMRKACGGYVPTRVVRSQPLALPDDKTYATVKKGTGQQSIATTMAFVR
LLKDLMRDKEIGRRFVLIAPDEYRTFGMDSFFPSAKIYNPLGQQYESVDRELLLAYKESP
TGQMLHDGISEAGCTASLIAAGSAYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLSR
GFVLGATAGRTTLTGEGLQHADGHSQLLASTNPACVAYDPAYAYEIAHIVQDGLRRMYGG
DSEHPHGEDVFYYLTVYNEPIQHPAEPADVDVEGILKGLHRISAGTAGAVAVQIMASGVA
VPWALEAQRILAEDWNVRADVWSATSWNELRREAVAVEEHNLLHPEEEQRVPWVTQKLSG
AEGPFVAVSDWMRSVPDQIARWVPGTYQSLGADGFGFADTRGAARRFFHIDAPSIVVAVL
TELAREGKVDRSALKQAIDRYRLLDVSAADPGAAGGDA
NT seq
2637 nt
NT seq
+upstream
nt +downstream
nt
gtggacgagcgcggccgggagcgggcccgctatctcatgctgcgcctgatcgagcgggcc
cgcgagaagcgcgtggccgtgcccgagatgcgcagcacggactacgtcaacacgatcccc
accaagagcgagccgttcttcccgggcaacgaggagatcgagcgcaagatcctgaacgcc
acgcgctggaacgcggccgtgatggtctcccgcgcgcagcgccccggcatcggggtcggc
ggccacatcgccaccttcgcctcctccgcctcgctgtacgacgtcggcttcaaccacttc
ttccgcggcaaggacgacggcaaaggcggcgaccaggtcttcttccaggggcacgcctcc
cccggcatctacgcgcgcgcctttctgctcgaccggctcagcgccgagcagctcgacggc
ttccgccaggagaagtcgaagtacccgaacgggctctccagctacccgcacccgcgctcc
atgccggacttctgggagttcccgacggtctcgatgggcctcggcccgctcggtgcgatc
ttccaggcgcggatgaaccgctacatggaggcgcgcggcatcgccgacacctccgactcg
cacgtgtgggcgttcctcggggacggcgagatggacgagccggagtcgctcggccagctc
agcatcgccgcgcgcgagggcctggacaacctgaccttcgtcgtcaactgcaacctccag
cgcctggacggcccggtgcgcggcaacggcaagatcatccaggagctggagtcggtcttc
cggggcgccggctggaacgtgatcaagctgatctgggaccgcacctgggacccgctgctc
gcccaggaccgcgacggcgtcctggtgaaccggatgaacacgaccccggacgggcagttc
cagacgtacgccaccgagtccggctcctacatccgtgagcacttcttcggcgacgacctg
cggctgcgcgcgatggtcgagaacatgaccgacgaccagatcctgcacctgggccgcggc
ggtcacgaccaccgcaagatctacgcggcgttcaaggcggccaaggagcacaagggccag
cccacggtcatcctggccaagacggtcaagggatggacgctgggcccgaacttcgagggc
cgcaacgccacgcaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgac
cggctgcacctgccgatctccgacaaggagctggagtccggcgccccgccgtactaccac
ccgggccgggagacggaggagatccagtacatgcacgacatgcgcaaggcgtgcggcggg
tacgtcccgacgcgtgtcgtgcgctcccagccgctcgcgctgccggacgacaagacgtac
gccaccgtgaagaagggcaccggtcagcagtccatcgccaccacgatggcgttcgtccgg
ctgctcaaggacctcatgcgggacaaggagatcggcaggcggttcgtgctgatcgcgccg
gacgagtaccgcacgttcggcatggactcgttcttcccgagcgcgaagatctacaacccg
ctcggccagcagtacgagtcggtggaccgggagctgctgctcgcctacaaggagtcgccg
accggccagatgctgcacgacggcatctcggaggcgggctgcacggcctcgctgatcgcg
gcgggctccgcctacgccacgcacggcgagccgctgatcccggtctacgtcttctactcg
atgttcggtttccagcgcaccggtgaccagttctggcagatggccgaccagctctcgcgc
ggtttcgtcctgggcgcgaccgcgggccgtacgaccctgaccggtgaggggctgcagcac
gccgacgggcactcgcagctgctggcctccaccaacccggcgtgcgtcgcgtacgacccg
gcctacgcctacgagatcgcccacatcgtccaggacggcctgcgccggatgtacggcggc
gacagcgagcacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagccc
atccagcacccggccgagccggccgacgtggacgtcgagggcatcctcaagggcctccac
cggatctcggcgggcacggccggtgccgtcgcggtgcagatcatggcgtccggtgtcgcg
gtgccgtgggccctggaggcgcagcgcatcctcgccgaggactggaacgtccgggccgac
gtctggtcggcgacgtcgtggaacgagctgcgccgcgaggccgtcgccgtggaggagcac
aacctgctgcacccggaggaggagcagcgggtgccgtgggtgacgcagaagctgagcggg
gccgagggtccgttcgtggccgtgtccgactggatgcggtcggtcccggaccagatcgcc
cggtgggtgcccgggacgtaccagtcgctgggcgcggacggcttcggcttcgccgacacc
cggggcgcggcccgccgcttcttccacatcgacgccccgtcgatcgtggtggcggtgctg
accgagctggcccgggagggcaaggtcgaccggtcggcgctgaagcaggcgatcgaccgt
taccggctgctggacgtctcggcggcggacccgggggccgcgggcggcgacgcgtag
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