Salicibibacter cibarius: HUG15_04075
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Entry
HUG15_04075 CDS
T07370
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scia
Salicibibacter cibarius
Pathway
scia00300
Lysine biosynthesis
scia00550
Peptidoglycan biosynthesis
scia01100
Metabolic pathways
scia01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scia00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HUG15_04075
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HUG15_04075
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HUG15_04075
Enzymes [BR:
scia01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HUG15_04075
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QQK74863
UniProt:
A0A7T6Z0T1
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Position
797882..799483
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AA seq
533 aa
AA seq
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MSNLLILLLIAAWAWYTIIRVKKNVHMLQLNAYRTERYFRWMKEHPEKAMYPRDVWPALA
LVFLLPFWGFSATWALTLAALWAIAAYGLLIVTRPKAAEKKKLVYTPRVKRLLVATGILY
VLILAIAWLIGVNAFVALLLLLVAANILAFFIVMIANVINLPVESQINQRYFNDAESIVE
SMPDLEVIGITGSFGKTSTKHILKAVLAAEYNVLMTPESYNTKMGVTRTIREHLKPYHDL
FIAEMGAKQENDIAEICELVHQKYGVLTAIGEQHLETFKTLENIKKTKFELVETLPEDGT
AFLNKDDENIRAYPQMNNCRTMYYGIDADDLHYRATEIAYSAKGTTFKVLKYDGSSVMIE
TKLLGRHNIYNILAAVAIGSEKNIPLEKIARAIKGVPPVPHRLELKKSSEKLTIIDDSFN
SNPTGSKMAVEVLGSMPEKKVLVTPGMIELGEKEYELNKTLAHHAAGVCDFIILVGKKQT
EPLQDGLTEAEYPQARYYVAADLQDALQKMREVTATEPSVVLLENDLPDTFNE
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgagtaacctattgattcttttacttattgccgcttgggcttggtatacgattatccgt
gtgaaaaagaacgtgcatatgctccaactcaatgcatatcgaacggagcggtatttccgc
tggatgaaagagcacccggaaaaagcaatgtatccgcgtgacgtgtggccggcgcttgcg
cttgttttcttgttgccgttctgggggttctcagctacttgggccttaacgcttgcggca
ttatgggcgatcgcggcctatggtttgctcatcgtcacgcggccgaaagccgcggagaaa
aagaagcttgtttatacaccgcgcgtgaaaaggctgttggtcgcaacgggcatcctttat
gtgcttatcctcgcgattgcatggctaattggcgttaatgccttcgtcgcccttttgctt
ttgttggttgcggctaatattcttgctttttttatcgttatgattgcaaatgtcatcaat
ttgccggtcgagtcgcagattaatcaacgttattttaatgatgccgaaagcatcgtggaa
tcgatgcccgatcttgaagtaatcggcatcacgggaagctttggaaaaacgagcacgaag
catattttaaaggctgtattggcagctgagtacaacgttctcatgactccggaaagctac
aatacgaaaatgggggttacaagaacgattcgggaacatttgaagccgtatcacgatctg
tttattgccgagatgggcgcgaaacaagagaatgatattgcagagatttgtgaacttgtt
catcaaaaatacggcgtgcttaccgcgatcggggaacagcatttagaaacgtttaaaacc
cttgaaaacataaaaaagacgaaatttgaactcgtggaaacactgccggaagatggaacg
gcttttctcaataaagatgatgaaaacatccgcgcgtatccgcaaatgaataattgccgc
acgatgtattacgggatcgatgccgatgatcttcattaccgtgcgacagaaatcgcgtat
tcggcaaaaggcaccacatttaaggtgctaaagtatgacggatcgagcgtgatgattgaa
acgaaattattgggcaggcataacatctataatattctcgcggctgtggcgattggatcg
gaaaagaacattccgctggaaaaaattgcccgggccattaaaggggttccgccggttccg
catcgtctcgaactgaaaaaatcgagcgaaaaactcactatcattgatgatagttttaat
tccaatccgaccggttcgaagatggccgtcgaggtgctgggatcgatgccggagaaaaaa
gtgctcgtcacgcccgggatgattgagttgggcgagaaagaatatgagcttaataaaaca
cttgcgcaccatgcggccggggtttgtgattttattattctcgttggcaaaaaacaaacc
gaaccgcttcaagacgggttaacggaagctgaatatccgcaggcgcgctattatgtggct
gcagatttgcaagatgcgttgcaaaaaatgcgcgaggtgacggcaacggaaccttccgtt
gtgctgctggaaaacgatttgccggatacgttcaatgaatag
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