Spermophilus citellus (European ground squirrel): 308632725
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Entry
308632725 CDS
T11988
Symbol
HK2
Name
(RefSeq) hexokinase-2
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
scil Spermophilus citellus (European ground squirrel)
Pathway
scil00010
Glycolysis / Gluconeogenesis
scil00051
Fructose and mannose metabolism
scil00052
Galactose metabolism
scil00500
Starch and sucrose metabolism
scil00520
Amino sugar and nucleotide sugar metabolism
scil00524
Neomycin, kanamycin and gentamicin biosynthesis
scil01100
Metabolic pathways
scil01200
Carbon metabolism
scil01250
Biosynthesis of nucleotide sugars
scil04066
HIF-1 signaling pathway
scil04910
Insulin signaling pathway
scil04930
Type II diabetes mellitus
scil04973
Carbohydrate digestion and absorption
scil05230
Central carbon metabolism in cancer
Module
scil_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
scil_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
scil_M01015
GDP-Man biosynthesis, Man => GDP-Man
Brite
KEGG Orthology (KO) [BR:
scil00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
308632725 (HK2)
00051 Fructose and mannose metabolism
308632725 (HK2)
00052 Galactose metabolism
308632725 (HK2)
00500 Starch and sucrose metabolism
308632725 (HK2)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
308632725 (HK2)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
308632725 (HK2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
308632725 (HK2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
308632725 (HK2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
308632725 (HK2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
308632725 (HK2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
308632725 (HK2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
scil04131
]
308632725 (HK2)
Enzymes [BR:
scil01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
308632725 (HK2)
Membrane trafficking [BR:
scil04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
308632725 (HK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
308632725
NCBI-ProteinID:
XP_081121174
LinkDB
All DBs
Position
13:complement(51614328..51674113)
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AA seq
917 aa
AA seq
DB search
MIASHMIACLFTELNHNQVQKVEQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAS
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDIMR
GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV
EGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGALNDIRTEFDREIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFQGKISPELLTTGSFETKDVSDIEDDKDGIRKAYQVLVRLG
LNPLQEDCVATHRICQIVSTRSANLCAATLAAVLRRIKENKGEDRLRSTIGVDGSVYKKH
PHFAKRLHKAVRRLVPDCDIRFLRSEDGSGKGAAMVTAVAYRLADQQRARQNTLEPLKLS
HEQLLEVKRRMKLEMERGLSKETHSIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDGEEGRMCVNMEWGAFGDNGCLDD
FRTEFDKAVDDLSLNPGKQKFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCEVSFLESEDGSGKG
AALITAVACRIREAGQR
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgattgcctcgcatatgatcgcctgcctcttcacggagctcaaccataaccaagtgcag
aaagttgagcagtatctctaccacatgcgtctctccgatgaaacccttttggagatttct
aagcggttccgcaaggagatggaaaaagggcttggagctaccacccaccccactgcttca
gtgaaaatgctaccaacttttgtgaggtccaccccagatgggacagaacatggagagttc
ctggctctggatcttggagggaccaacttccgtgtgctccgtgtgagagtaacggacaat
gggctccagaaggttgagatggagaaccagatctacgccatccctgaggacatcatgcga
ggcagtggcactcagctgtttgaccacattgctgaatgcctggccaacttcatggataag
ctccaaatcaaagacaagaagctcccattgggctttaccttctcattcccctgccaccag
actaagctagatgagagtttcctggtctcatggaccaaaggcttcaagtccagtggtgtg
gaaggcagggacgtggtggctctgatccggaaggccatccagcggagaggggactttgat
attgacattgtggctgtggtgaatgacacggttgggaccatgatgacttgtggttatgat
gaccagaactgtgagattggtctcattgtgggcactggcagcaatgcctgctacatggag
gaaatgcgccacatcgacatggtggagggcgacgaggggcggatgtgtatcaacatggag
tggggggcctttggggacgatggcgcgctcaatgacatccgcacggaatttgaccgagag
atcgacatgggctcgctgaatcctgggaagcaactgtttgagaagatgatcagtgggatg
tacatgggggagctggtaaggctcatcctggtgaagatggccaaggaagagctgctgttc
caggggaagatcagcccagaactgcttaccacaggcagcttcgaaaccaaagatgtctca
gatattgaagacgataaggatggcatccggaaggcctaccaggtgctggtgcggctgggt
ctgaatccattgcaggaggactgtgtggccactcaccggatctgccagattgtgtccaca
cgctcagccaacctgtgtgcagccaccctggctgctgtgctgcggcgtatcaaggagaac
aagggcgaggatcggctgcgctccaccattggggttgatggctccgtctacaagaaacac
cctcattttgccaagcgtcttcacaaggctgtacgtcggctggtgcctgactgcgacatt
cgcttcctccgctctgaggatggcagcggcaaaggggcagccatggtgaccgcagtggct
taccgactggctgatcaacaaagagcccgccagaataccctagagcctctaaaactgagc
catgagcagctgctggaggtcaagaggaggatgaagcttgaaatggagcgaggtctgagc
aaggagacgcactccatcgctcctgtgaagatgctgcccacctacgtgtgtgctaccccc
gatggcacagagaaaggggacttcttggccttggaccttggaggaaccaatttccgggtc
ctgctggtgcgtgtgcgaaatgggaagcggcgaggagtagagatgcacaacaagatctac
tccatcccacaggaggtcatgcatggcacaggcgaggagctctttgaccacatcgtccag
tgcatcgctgacttcctggagtacatgggcatgaagggtgtgtctctgcctctgggtttc
accttctccttcccctgccagcagaacagcttggatgagagtatcctccttaagtggacc
aaaggcttcaaggcatctggatgtgagggtgaggatgtggtcaccctgctgaaggaagcg
atccaccggcgagaggagtttgacctggacgtggtggctgtggttaatgacacagttgga
actatgatgacgtgtggctatgaagaccctcactgtgaggttggcctcattgttggcacg
ggtagcaacgcctgctacatggaggagatgcgcaacgtggagctggtggatggagaagag
gggcggatgtgcgtcaacatggaatggggggccttcggggacaatggatgcctggacgac
ttccgcacggaatttgacaaggctgtggatgatctttcgctcaacccgggcaaacagaag
tttgagaagatgatcagtggcatgtacttgggcgagattgttcgtaacatccttatcgat
ttcaccaagcgtgggctgctcttccgcggccgcatctcagagcggctcaagacaagggga
atctttgaaacaaagttcttgtctcagattgagagcgattgcttggccctgctgcaggtc
cgtgccatcctgcaccacttgggcctcgagagtacctgtgacgacagcatcatcgtcaag
gaggtgtgcaccgtggtggcacggcgggcagcccagctctgtggcgcaggcatggctgct
gttgtggacaagatacgggaaaaccgtgggctggacaccctcaaagtgacagtgggtgtg
gatgggaccctctacaagctacatcctcattttgccaaagtcatgcatgagacggtgaag
gacctggcccccaaatgtgaggtgtccttcctggagtcagaggacggcagtgggaagggg
gccgcgctcatcactgccgtggcctgtcgcatccgtgaggccggacagcgatag
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