Streptomyces cinereoruber: CP977_10725
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Entry
CP977_10725 CDS
T07115
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
scin
Streptomyces cinereoruber
Pathway
scin00010
Glycolysis / Gluconeogenesis
scin00020
Citrate cycle (TCA cycle)
scin00620
Pyruvate metabolism
scin00785
Lipoic acid metabolism
scin01100
Metabolic pathways
scin01110
Biosynthesis of secondary metabolites
scin01120
Microbial metabolism in diverse environments
scin01200
Carbon metabolism
scin01210
2-Oxocarboxylic acid metabolism
Module
scin_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
scin00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP977_10725 (aceE)
00020 Citrate cycle (TCA cycle)
CP977_10725 (aceE)
00620 Pyruvate metabolism
CP977_10725 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP977_10725 (aceE)
Enzymes [BR:
scin01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP977_10725 (aceE)
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Ortholog
Paralog
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QEV32591
UniProt:
A0AAV4KR64
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All DBs
Position
2416033..2418765
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AA seq
910 aa
AA seq
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MAPGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRARARYLMLRLIERAREK
RVAVPEMRSSDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAYLLDRLNEAQLDGFRQ
ERSKFPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEVESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESIFRGN
GWNVIKLIWDRSWDPLLAQDRDGILVNKLNTTPDGQFQTYATETGGYIRDHFFGDDHRLR
AMVEGMSDQQVLHLGRGGHDHRKIYAAYAAAKAHAGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHIPITDKQLEEGLPPYYHPGRDSEEIQYMHDRRKALGGYVP
TRVVRAEPLELPDDKAYAAAKKGSGQQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSHLLASTNPACIAYDPAFGFEIAHIVKDGLRRMYGPEAEDVFYYLTVYNEPIQHPAEPE
DVDVEGILQGIHRFKPAESGTIPAQILASGVGVPWAIEAQRILAEEWNVRADVWSATSWT
ELRREAVAVEEHNLLHPDEEQRVPYVTRKLQGAEGPFVAVSDWMRAVPDQISRWVPGTYT
SLGADGFGFADTRGAARRYFHIDAQSIVLAVLTELAREGKVERSVLKQAVDRYQLLDVAA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggctcccggatccgatcgcaacccgatcatcattggcggccttcccagccaggtcccg
gacttcgatccggaagagacccaggaatggctcgactccctcgacgctgccgtcgacgag
cggggccgggcacgcgcccgctacctcatgctccgcctgatcgagcgcgcccgcgagaag
cgcgtggccgtgcccgagatgcgcagctcggactacgtcaacaccatcgccaccaaggac
gagcccttcttccccggcaacgaggagatcgagcgcaaggtcctcaacgccacccggtgg
aacgcggccgtgatggtctcgcgcgcccagcgcccgggcatcggcgtcggtggccacatc
gccaccttcgcctcctccgcctccctctacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctcccccggcatc
tacgcccgcgcgtacctgctggaccggctgaacgaggcccagctcgacggcttccgccag
gagaggtcgaagttcccgaacggcctctcctcctatccgcacccgcggctgatgccggac
ttctgggagttcccgacggtgtcgatgggcctcggcccgctcggcgcgatctaccaggcc
cggatgaaccgctacatggaggctcgcggcatcgccgacacctccaagtcgcacgtgtgg
gcgttcctcggcgacggcgagatggacgaggtggagtccctcggccagctgtccatcgcg
gcccgcgagggcctggacaacctcaccttcgtcgtcaactgcaacctccagcggctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgatcttccggggcaac
ggctggaacgtcatcaagctgatctgggaccgctcctgggacccgctgctcgcgcaggac
cgggacggcatcctggtcaacaagctgaacaccaccccggacgggcagttccagacgtac
gccacggagaccggcggctacatccgggaccacttcttcggcgacgaccaccggctgcgg
gccatggtcgagggcatgtcggaccagcaggtcctgcacctgggccgcggcggccacgac
caccggaagatctacgcggcctacgcggcggcgaaggcccacgccggccagccgaccgtg
atcctcgcgcagaccgtcaagggctggacgctcggcccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccggctgcac
atcccgatcacggacaagcagctggaggagggcctgcccccgtactaccacccgggccgg
gactccgaggagatccagtacatgcacgaccgccgcaaggcgctcggcgggtacgtgccg
acccgggtcgtgcgggcggagccgctggagctccccgacgacaaggcctacgcggcggcc
aagaagggctcgggccagcagtcgatcgccaccaccatggcgttcgtccgcatcctgaag
gacctcatgcgggacaaggagatcggcaagcgcttcgtgctgatcgcccccgacgagtac
cgcaccttcggcatggacgcgttcttcccgagcgccaagatctacaacccgctgggccag
cagtacgaggcggtggaccgcgaactcctcctcgcctacaaggagtcgccgaccggccag
atgctgcacgacggcatctcggaggccggctgcacggcctcgctgatcgccgccggctcc
gcgtacgccacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggc
ttccagcggaccggcgaccagttctggcagatggccgaccagctggcgcgcggcttcgtc
ctcggcgccaccgccggccgcacgacgctgaccggcgagggcctccagcacgcggacgga
cactcccacctcctcgcttccaccaaccctgcctgcatcgcctacgacccggcgttcggc
ttcgagatcgcgcacatcgtcaaggacggcctgcgccggatgtacggccccgaggccgag
gacgtcttctactacctgaccgtctacaacgagccgatccagcacccggccgagccggag
gacgtggacgtggagggcatcctccagggcatccaccgcttcaagccggccgagtcgggc
acgatccccgcgcagatcctggcctccggcgtcggcgtgccgtgggcgatcgaggcccag
cggatcctcgccgaggagtggaacgtgcgggccgacgtctggtccgccacctcctggacc
gagctgcgccgcgaggccgtggccgtcgaggagcacaacctgctccacccggacgaggag
cagcgcgtcccgtacgtgacgcgcaagctccagggcgccgagggcccgttcgtggcggtc
tcggactggatgcgcgcggtgccggaccagatctcccgctgggtccccggcacgtacacc
tcgctgggcgcggacggcttcggcttcgcggacacgcggggcgcggcccgtcgctacttc
cacatcgacgcccagtcgatcgtgctcgcggtgctgaccgagctggcccgcgagggcaag
gtcgagcggtcggtcctgaagcaggccgtggaccgctaccagctgctcgacgtggcggcg
gcggacccgggcgcggcgggcggcgacgcgtga
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