Streptomyces cinereoruber: CP977_23420
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Entry
CP977_23420 CDS
T07115
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scin
Streptomyces cinereoruber
Pathway
scin00020
Citrate cycle (TCA cycle)
scin00630
Glyoxylate and dicarboxylate metabolism
scin00785
Lipoic acid metabolism
scin01100
Metabolic pathways
scin01110
Biosynthesis of secondary metabolites
scin01120
Microbial metabolism in diverse environments
scin01200
Carbon metabolism
scin01210
2-Oxocarboxylic acid metabolism
Module
scin_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scin_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scin00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CP977_23420
00630 Glyoxylate and dicarboxylate metabolism
CP977_23420
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP977_23420
Enzymes [BR:
scin01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CP977_23420
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CP977_23420
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CP977_23420
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CP977_23420
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QEV34752
UniProt:
A0AAV4KDE0
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All DBs
Position
complement(5161236..5165060)
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AA seq
1274 aa
AA seq
DB search
MSSQSPSTPSSPTDQDGQGQNPATAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GASETPAAPAPTQSTPSAPAAQQTGPAQAAPAAPASVPAPAPAPAAQKPAAAPAAPAAVK
AAPAAAKPAAAQAAPAAAKPAAKAAPASETPAGPELVTLRGPAAAVAKNMNASLEVPTAT
SVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNHSFAEKDGKP
TLVKPEHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVKRARVGKLTME
DFSGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVM
TLTSTYDHRVIQGAASGEFLRIVANLLLGEEGFYDEIFKALRIPYEPVRWLRDIDASHDD
DVTKAARVFELIHSYRVRGHVMADTDPLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFA
GKSMMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRVERPHSRVEREEQLRILRR
LNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNV
LANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHL
EAVDPVLEGVVRAKQDVINKGGTDFTVLPIALHGDAAFAGQGVVAETLNMSQLRGYRTGG
TVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQT
FNKDVVIDLICYRRRGHNEGDNPSFTNPQMYNLIDKKRSVRKLYTESLIGRGDITLEEAE
QSLQDFQGQLEKVFAEVREATTASSAPVHVPDAQAEFPVSVTTAVSQEVVKRIAESQVNV
PDRITVHPRLLPQMQRRAASIDDGTIDWGFGETLAIGSLLMEGTPVRLSGQDSRRGTFGQ
RHAVLVDQETGEDHTPLLYLAEDQAHYNVYDSLLSEYAAMGFEYGYSLARPDALVVWEAQ
FGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDN
MTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKVEEFTTGGFRPVIGD
DTVDPAAVRKVVFCAGKVYYDLEAERQKRGVTDTAIIRLERLYPLPGAELQAEIAKYPNA
EKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADIPAGERLRRISRPHSSSPAVGSAKRH
QAEQQQLVDEVFDA
NT seq
3825 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaccccgagctccccgaccgaccaagacgggcagggccag
aaccctgcgaccgccttcggtgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaattcggtcgatcgtgcctggtgggacttcttcgccgactacaagccc
ggagcgtcggagaccccggccgccccggcgcccacccagagcacgccgagcgcccccgcc
gcgcagcagacgggccccgcacaggccgcgcctgccgctccggcctccgtgcccgcgccc
gctccggctcccgccgcacagaagccggccgcggctcccgccgccccggccgcggtgaag
gcggcccccgcggccgccaagccggccgccgcacaggccgctccggccgccgcgaagccc
gccgccaaggccgccccggcttccgagaccccggccggtcccgagctggtcacgctgcgc
ggccccgccgccgcggtcgcgaagaacatgaacgcctccctggaggtgccgacggccacg
tccgtccgcgccgtcccggtgaagctgctcttcgacaaccggatcgtgatcaacaaccac
ctgaagcgcgcccggggcgggaagatctccttcacccacctcatcggctacgcgatggtg
caggccatcaaggccatgccgtccatgaaccactccttcgcggagaaggacggcaagccg
accctggtcaagccggagcacgtgaacttcggcctcgcgatcgacctggtgaagcccaac
ggcgaccgccagctcgtcgtcgcgggcatcaagaaggccgagacgctcaacttcttcgag
ttctggcaggcgtacgaggacatcgtcaagcgcgcccgcgtgggcaagctgacgatggag
gacttctccggcgtcaccgtctccctgaccaaccccggcggcctcggcacggtccactcc
gtgccgcgtctgatgcccggacagtcggtcatcatgggcgtcggctcgatggactacccg
gccgagttccagggcacctcccaggacaccctgaacaagctgggcatctccaaggtcatg
accctgacctcgacgtacgaccaccgcgtgatccagggcgccgcctccggcgagttcctg
cggatcgtcgcgaacctcctcctcggcgaggagggcttctacgacgagatcttcaaggcc
ctgcgcatcccctacgagccggtccgctggctccgcgacatcgacgcctcccacgacgac
gacgtcaccaaggccgcgcgcgtcttcgagctgatccactcctaccgggtccgcggccac
gtcatggccgacaccgacccgctggagtacaagcagcgcaagcaccccgacctggacatc
accgagcacggcctcaccctgtgggacctggagcgcgagttcgcggtcggcggcttcgca
ggcaagtcgatgatgaagctccgcgacatcctcggcgtgctccgcgactcgtactgccgc
accaccggcgtcgagttcatgcacatccaggacccgaagcagcgcaagtggatccaggac
cgcgtcgagcgcccgcactcccgcgtggagcgcgaggagcagctgcggatcctgcgccgc
ctgaacgcagccgaggccttcgagaccttcctgcagaccaagtacgtcggccagaagcgc
ttctccctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactcggcc
gccgagtcgcgcctcgacgaggtcgtcatcggcatggcccaccgcggccggctgaacgtc
ctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctc
gacccgaagtcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggcacc
ttcacgggcctggacggcgagcagatcaaggtctccctggtcgccaacccctcgcacctg
gaggcggtcgacccggtcctggagggtgtcgtccgcgccaagcaggacgtcatcaacaag
ggcggcacggacttcaccgtcctgccgatcgccctccacggcgacgcggccttcgccggc
cagggcgtcgtcgccgagacgctgaacatgtcgcagctgcggggctaccgcaccggcggc
acggtccacatcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcctcgcgt
tcctcgatgtacgcgaccgacgtggcccgcatgatcgaggcgccgatcttccacgtgaac
ggcgacgacccggaggccgtggtccgcgtcgcgcggctcgccttcgagttccgccagacg
ttcaacaaggacgtcgtgatcgacctcatctgctaccgccgccgcggccacaacgagggc
gacaacccctcgttcaccaacccgcagatgtacaacctgatcgacaagaagcgttcggtg
cgcaagctgtacaccgagtcgctcatcggtcgcggggacatcaccctggaggaggcggag
cagtcgctccaggacttccagggccagctggagaaggtgttcgcggaggtccgcgaggcc
accaccgcctcctcggctccggtgcacgtcccggacgcccaggccgagttcccggtctcc
gtcaccaccgcggtctcccaggaggtcgtgaagcggatcgccgagtcccaggtcaacgtc
ccggaccggatcacggtccacccgcgtctgctcccgcagatgcagcgccgcgccgcgtcc
atcgacgacggcaccatcgactggggcttcggcgagaccctcgccatcggctccctgctg
atggagggcaccccggtccggctctccggccaggactcccgccgcggcaccttcggccag
cgccacgcggtcctggtggaccaggagaccggcgaggaccacaccccgctgctctacctg
gccgaggaccaggcccactacaacgtctacgactcgctgctcagcgagtacgcggcgatg
ggcttcgagtacggctactcgctggcccgcccggacgccctggtcgtctgggaggcccag
ttcggcgacttcgtcaacggcgcgcagaccgtcgtcgacgagttcatctcctccgccgag
cagaagtggggccagacctccggcgtcacgctgctcctgccgcacggctacgagggccag
ggcccggaccactcgtccgcgcgcccggagcgcttcctccagatgtgcgcccaggacaac
atgacggtcgccatgccgacgctgccgtcgaactacttccacctcctgcgctggcaggtg
cacaacccgcaccacaagccgctcatcgtcttcaccccgaagtcgatgctgcgcctgaag
gccgcggcgtccaaggtggaggagttcaccaccggcggcttccgcccggtgatcggcgac
gacacggtcgacccggccgccgtccgcaaggtcgtcttctgcgcgggcaaggtctactac
gacctggaggccgagcgtcagaagcgcggtgtcacggacacggcgatcatccgactggag
cgcctgtacccgctgccgggtgccgagctccaggccgagatcgccaagtacccgaacgcc
gagaagtacctgtgggcccaggaggagccggcgaaccagggtgcctggccgttcatcgcg
ctcaacctgatcgaccacctcgacctggcggtcggcgcggacatcccggcgggcgagcgc
ctgcgccggatctcgcgtccgcactcctcctccccggcggtcggctcggccaagcgccac
caggcggagcagcagcagctcgtcgacgaggtcttcgacgcctga
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