Streptomyces cinnabarinus: STRCI_006121
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Entry
STRCI_006121 CDS
T08957
Name
(GenBank) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
KO
K05551
minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
scir
Streptomyces cinnabarinus
Pathway
scir00253
Tetracycline biosynthesis
scir01056
Biosynthesis of type II polyketide backbone
scir01100
Metabolic pathways
scir01110
Biosynthesis of secondary metabolites
Module
scir_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
scir00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
STRCI_006121
00253 Tetracycline biosynthesis
STRCI_006121
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
scir01004
]
STRCI_006121
01008 Polyketide biosynthesis proteins [BR:
scir01008
]
STRCI_006121
Enzymes [BR:
scir01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
STRCI_006121
2.3.1.260 tetracycline polyketide synthase
STRCI_006121
Lipid biosynthesis proteins [BR:
scir01004
]
Polyketide synthase
Component type
STRCI_006121
Polyketide biosynthesis proteins [BR:
scir01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
STRCI_006121
Nonaketide PKS
STRCI_006121
Decaketide PKS
STRCI_006121
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
WAZ24677
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All DBs
Position
6742454..6743713
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AA seq
419 aa
AA seq
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MTRRAVITGLGVVAPGGIGTKDYWALLTGGRAATRHITFFDAAGYRSRVAAEVDFDPAAA
GLGVREIHRMDRSAQFAVVSAWEAVADSGLALGGLDPLRTGVSIGSAVGAATSLDQAYPL
LSDEGRDWRTDTTYAVPQLYDYMVPSALAREVAWTVAAQGPVALVSTGCTSGLDALGHAA
GIIAEGSADVMLAGAAEAPVCAITAASFDAIKATTPYEGDDPAEACRPFDLTRDGFVLGE
GGAILVVEEKEHARRRGAHVYAEIAGFATRGNAFHMTGLRPDGTELAAAVGAALDEARLP
ADAVDYVNAHGSGTRQNDVHETNALKLSLGSHAYDVPVSSIKSMIGHSLGAIGSLEAAAC
ALALEHGAVPPTANLHTPDPECDLDYVPLTARAQPLNTVLSVGSGFGGLQSALVLRKPE
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
atgacccgacgcgcagtgatcacagggctgggtgtggtcgcccccggtggcatcggcacc
aaggactactgggcgctgctcaccggcggccgggccgcgacccggcacatcaccttcttc
gacgccgccggctaccgctcccgcgtcgccgccgaggtcgacttcgaccccgcggccgcc
ggactcggcgtccgggagatccaccgcatggaccgctcggcgcagttcgccgtggtcagc
gcctgggaggcggtcgcggacagcggactcgccctcggcggcctggacccgctgcgcacc
ggcgtcagcatcggcagcgccgtcggcgccgccaccagcctggaccaggcctacccgctg
ctcagcgacgagggccgggactggcgcaccgacaccacctatgccgtaccgcagctgtac
gactacatggtgccgagcgcgctcgcccgcgaggtcgcctggaccgtcgccgcgcaggga
ccggtcgcgctggtctccaccggctgcacctccggcctggacgccctcggccacgccgcc
gggatcatcgcggaggggtcggcggacgtgatgctggccggcgccgcggaggcgcccgtg
tgcgccatcaccgcggcctccttcgacgccatcaaggccaccaccccctatgaaggggac
gaccccgccgaggcctgccggcccttcgacctcacccgcgacggattcgtgctcggcgag
ggcggcgccattctcgtggtggaggagaaggagcacgcccgccgccgcggcgcgcacgtc
tacgccgagatcgccgggttcgccacccgcggcaacgccttccacatgaccggactgcgc
cccgacggcaccgaactggccgccgcggtcggggccgccctcgacgaggcccggctgccc
gccgacgccgtcgactacgtcaacgcgcacggctccgggacccggcagaacgacgtccac
gagaccaacgcgctcaagctgagcctcggctcgcacgcctacgacgtgccggtcagctcc
atcaagtcgatgatcggccactcgctcggcgcgatcggctcactggaggccgccgcctgc
gccctggccctggagcacggtgccgtcccgcccaccgcgaaccttcacaccccggacccg
gaatgcgatctcgactacgtacccttgaccgcgcgggctcagcccctcaacacagtgctc
agcgtgggcagtggcttcgggggcctgcagagcgccctcgtgctgaggaagcccgaatga
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