Streptomyces clavuligerus: BB341_08105
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Entry
BB341_08105 CDS
T04717
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sclf
Streptomyces clavuligerus
Pathway
sclf00020
Citrate cycle (TCA cycle)
sclf00630
Glyoxylate and dicarboxylate metabolism
sclf00785
Lipoic acid metabolism
sclf01100
Metabolic pathways
sclf01110
Biosynthesis of secondary metabolites
sclf01120
Microbial metabolism in diverse environments
sclf01200
Carbon metabolism
sclf01210
2-Oxocarboxylic acid metabolism
Module
sclf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sclf_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sclf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
BB341_08105 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
BB341_08105 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BB341_08105 (kgd)
Enzymes [BR:
sclf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
BB341_08105 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
BB341_08105 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
BB341_08105 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
BB341_08105 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ANW18191
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All DBs
Position
2105856..2109719
Genome browser
AA seq
1287 aa
AA seq
DB search
MSSQSPSNSSSPSLRPGGAPTTDESAQGAGPAAAFGPNEWLVDEIYQQYLQDPNSVDRAW
WDFFADYKPGAQNTAATGAEPTAEAPAAAPAPTAPAPRASANGATVPAAPAAPAAPAVAA
APAPAPAAPKPVPAAAPAPAPAPVAAPKPAAAPAPAAEAPAGPELITLRGPAAAVAKNMN
ASLEMPTATSVRAVPVKLLFDNRIVINNHLKRARGGKVSFTHLIGYAMVRALKAMPSMNW
SFALKDGKPTLVKPEHVNFGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRR
ARGNKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTL
NKLGISKVMTLTSTYDHRVIQGAASGEFLRVVANSLLGEDGFYDDIFEALRIPYEPVRWL
KDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLE
REFAVGGFAGKSLMKLRDVLGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHAKPER
EEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIG
MAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKV
SLVANPSHLEAVDPVLEGVVRAKQDVINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMS
QLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEACVRVA
RLAFEFRQTFNKDVVIDLICYRRRGHNEGDNPQFTNPQMYNLIDKKRSVRKLYTESLIGR
GDITLEEAEQALQDFQGQLEKVFAEVREATSLPAPAQVPDPQAEFPVAVTTAVSQEIVKR
IAESQVNIPDNVAVHPRLLPQLQRRASSVEDGTIDWGMGETLAIGSLLMEGTPVRLSGQD
TRRGTFGQRHAVLVDQETGEDYTPLLYLTEEQARYNVYDSLLSEYAAMGFEYGYSLARPD
ALVVWEAQFGDFVNGAQTVVDEFISSAEQKWGQHSGVTLLLPHGYEGQGPDHSSARPERF
LQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAQSKTEEFLTG
GFRPVIGDTGVDAGTVDPAGVRKVVFTSGKVYYDLDAERKKRGTQDTAIIRLERLYPLPG
AELQAEIAKFPNAEKYIWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRP
HGSSPAVGSKKRHEQEQEQLVNEVFDA
NT seq
3864 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactccagctcgcccagcctccggccgggtggtgccccc
acgaccgacgaaagcgcgcagggcgccggtcccgccgccgctttcgggcccaatgagtgg
cttgtcgacgagatctaccagcagtacctccaggacccgaactcggtcgaccgggcctgg
tgggacttcttcgccgactacaagcccggcgcgcagaacaccgccgccaccggggccgag
cccaccgcggaggctcccgccgcggcccccgcgccgaccgctcccgccccccgggcgagc
gccaacggtgccaccgtgcccgccgccccggccgcccccgcggccccggccgtggctgcg
gcaccggctccggcccccgcagcgccgaagcccgtgcccgccgccgccccggccccggcc
ccggccccggtcgccgcgccgaagccggccgcggctcccgcgccggccgccgaggcaccc
gcgggtcccgagctgatcaccctgcgcggcccggccgccgccgtcgcgaagaacatgaac
gcctcgctggagatgcccacggccacgtccgtgcgcgccgtcccggtgaagctgctcttc
gacaaccgcatcgtcatcaacaaccatctgaagcgcgcccggggcgggaaggtctccttc
acccacctcatcggctacgcgatggtgcgggccctcaaggccatgccgtcgatgaactgg
tccttcgcgctgaaggacggcaagccgacgctggtcaagccggagcatgtgaacttcggc
ctcgccatcgacctggtcaagcccaacggcgaccgccagctcgtcgtcgcggccatcaag
aaggccgagacgctcaacttcttcgagttctggcaggcgtacgaggacatcgtccgccgc
gcccggggcaacaagctcacgatggacgacttcaccggggtcacggtctccctgaccaac
cccggcggcctcggcaccgtccactccgtgccgcggctgatgcccggccagtccgtgatc
atgggcgtcggctccatggactacccggccgagttccagggcacctcccaggacaccctg
aacaagctgggcatctccaaggtcatgacgctgacctcgacctacgaccaccgggtcatc
cagggcgcggcctccggcgagttcctgcgggtcgtggccaactcgctgctgggcgaggac
ggcttctacgacgacatcttcgaggcgctgcgcatcccgtacgagccggtccgctggctc
aaggacatcgacgcctcccacgacgacgacgtcaccaaggccgcccgggtcttcgagctg
atccactcctaccgggtccgcggccatgtcatggccgacaccgacccgctggagtaccgc
cagcgcaagcaccccgacctggacatcaccgagcacggcctcaccctgtgggacctggag
cgcgagttcgcggtcggcggcttcgcgggcaagtccctgatgaagctgcgcgacgtcctc
ggcgtgctgcgggactcgtactgccgcaccaccggcatcgagttcatgcacatccaggac
cccaagcagcgcaagtggatccaggaccgggtggagcgcccgcacgccaagccggagcgc
gaggagcagttgcgcatcctgcgccggctcaacgcggccgaggcgttcgagaccttcctc
cagacgaagtacgtcggtcagaagcggttctcgctggagggcggcgagtccgtcatcccg
ctgctggacgcggtcatcgactcggcggccgagtcccgcctcgacgaggtcgtcatcggc
atggcccaccgcggccggctgaacgtcctcgccaacatcgtcggcaagtcgtacgcgcag
atcttccgggagttcgagggcaacctcgacccgaagtcgatgcacggctccggtgacgtc
aagtaccacctgggcgccgaggggaccttcaccggtctcgacggtgagcagatcaaggtc
tccctggtcgccaacccctcccacctggaggccgtcgacccggtcctggagggtgtcgtc
cgcgccaagcaggacgtcatcaacaagggcggcacggacttcaccgtgctgccggtcgcc
ctccacggcgacgcggccttcgcgggccagggcgtggtcgccgagacgctgaacatgtcg
cagctccgcggctaccgcaccggcggcaccgtccatgtcgtcatcaacaaccaggtcggc
ttcaccgccgccccggagtcctcccgctcctcgatgtacgccaccgacgtggcccgcatg
atcgaggcgccgatcttccacgtcaacggcgacgacccggaggcgtgcgtccgggtggcg
cggctcgccttcgagttccgccagacgttcaacaaggacgtggtgatcgacctcatctgc
taccgccgccgcggtcacaacgagggcgacaacccgcagttcaccaacccgcagatgtac
aacctgatcgacaagaagcgttcggtgcgcaagctgtacaccgagtcgctgatcggccgg
ggggacatcacgctggaggaggccgagcaggccctccaggacttccagggccagttggag
aaggtcttcgccgaggtccgcgaggccaccagcctgcccgccccggcgcaggtccccgac
ccgcaggccgagttccccgtggcggtgaccacggcggtctcccaggagatcgtcaagcgg
atcgccgagtcccaggtgaacatcccggacaacgtcgccgtccacccgcggctgctgccg
cagctccagcggcgcgcctcctccgtcgaggacggcacgatcgactggggcatgggcgag
accctggccatcggctcgctgctgatggagggcaccccggtgcgcctctccggccaggac
acccgccgcggcaccttcggccagcgccacgcggtcctcgtcgaccaggagaccggcgag
gactacaccccgctgctctacctcaccgaggagcaggcccgttacaacgtgtacgactcg
ctgctcagcgagtacgcggcgatgggcttcgagtacggctactcgctggcccgcccggac
gcgctggtcgtgtgggaggcccagttcggtgacttcgtcaacggcgcccagaccgtcgtc
gacgagttcatctcctcggccgagcagaagtggggccagcactccggtgtgacgctgctg
ctgccgcacggctacgagggccagggcccggaccactcctcggcccgcccggagcgcttc
ctccagctctgcgcgcagaacaacatgacggtcgcgatgccgacgctgccgtcgaactac
ttccatctgctgcgctggcaggtgcacaacccgcaccacaagccgctgatcgtcttcacc
ccgaagtcgatgctccggctgaaggcggcgcagtcgaagacggaggagttcctgaccggc
ggcttccgcccggtgatcggggacaccggcgtcgacgcgggcacggtggacccggcgggc
gtgcgcaaggtcgtcttcacctccggcaaggtctactacgacctcgacgcggagcggaag
aagcgcggtacgcaggacaccgcgatcatccggctggagcggctgtacccgctgccgggt
gccgagctccaggccgagatcgccaagttcccgaacgcggagaagtacatctgggcccag
gaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccacctg
gacctggccgtcggcgcggacgtcccgcacggcgagcggctgcggcggatctcccgtccg
cacggctcgtccccggcggtgggctccaagaagcgtcatgagcaggagcaggagcagctc
gtcaacgaggtcttcgacgcctga
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