Streptomyces coelicolor: SCO2371
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Entry
SCO2371 CDS
T00085
Symbol
SCC8A.29
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sco
Streptomyces coelicolor
Pathway
sco00010
Glycolysis / Gluconeogenesis
sco00020
Citrate cycle (TCA cycle)
sco00620
Pyruvate metabolism
sco00785
Lipoic acid metabolism
sco01100
Metabolic pathways
sco01110
Biosynthesis of secondary metabolites
sco01120
Microbial metabolism in diverse environments
sco01200
Carbon metabolism
sco01210
2-Oxocarboxylic acid metabolism
Module
sco_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sco00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SCO2371 (SCC8A.29)
00020 Citrate cycle (TCA cycle)
SCO2371 (SCC8A.29)
00620 Pyruvate metabolism
SCO2371 (SCC8A.29)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SCO2371 (SCC8A.29)
Enzymes [BR:
sco01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SCO2371 (SCC8A.29)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
RL
Motif
Other DBs
NCBI-ProteinID:
CAB92847
Kitasato:
SCO2371
UniProt:
Q9KY19
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All DBs
Position
2539576..2542332
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AA seq
918 aa
AA seq
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MASASDRSDRSPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERA
REKRVAVPEMRSTDYVNTIPTKSEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVG
GHIATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAYLLDRLSEQHLDG
FRQEKSKAPYMLSSYPHPRSMPDFWEFPTVSMGLGPIGAIFQARMNRYMHARGIADTSKS
HVWAFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESVF
RGAGWNVIKLVWDRTWDPLLAQDRDGVLVNRMNTTPDGQFQTYATESGAYIRDHFFGDDH
RLRAMVENMTDDQILHLGRGGHDHRKIYAAYKAALEHKGQPTVILAKTIKGWTLGPNFEG
RNATHQMKKLTVDDLKRFRDRLHLPISDKELESGPPPYYHPGRDTEEMQYMHDRRLGCGG
YVPTRVVRSKPLALPDDKTYATVKKGSGQQSIATTMAFVRLLKDLMRDKEIGRRFVLIAP
DEYRTFGMDSFFPSAKIYNPLGQQYESVDRDLLLAYKEAPNGQMLHDGISEAGCTASLIA
AGSAYATHGEPLIPVYVFYSMFGFQRTGDQFWQMGDQLARGFVLGATAGRTTLTGEGLQH
ADGHSQLLASTNPACVAYDPAFGFEIAHIVKDGLRRMYGGDEQHPHGEDVFYYLTVYNEP
IRHPAEPENVDVEGILKGVYRFSEGTGGSIPAQIMASGVAVPWAVEAQRILAEEWNVRAD
VWSATSWNELRREAVACEEHNLLHPEEEQRVPWVTRKLAGAQGPFVAVSDWMRSVPDQIA
RWVPGTYQSLGADGFGFADTRGAARRFFHIDAQSIVVGVLSELAREGKVDRSVLKQAIDR
YRLLDVTAADPGAAGGDA
NT seq
2757 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccgcatccgatcgcagtgatcgcagtccgatcatcattggcggccttcccagt
caggttcctgacttcgaccccgaggaaacccaggagtggctcgactcgctcgacgccgcc
gtcgacgagcgcggccgggaacgggcccgctacctgatgctgcggctgatcgagcgggcc
cgcgagaagcgcgtggccgtgcccgagatgcgcagcacggactacgtcaacaccatcccg
accaagagcgagccgttcttccccggcaacgaggagatcgaacgcaagatcctcaacgcc
acccgctggaacgcggcggtgatggtctcgcgcgcgcagcggcccgggatcggcgtcggc
ggccacatcgcgaccttcgcctcctccgcatccctgtacgacgtgggcttcaaccacttc
ttccggggcaaggacgagggcgacggcggagaccaggtcttcttccaggggcacgcctcc
cccggcatctacgcgcgcgcgtacctgctggaccggctgagcgagcagcacctggacggc
ttccgccaggagaagtccaaggcgccgtacatgctgtcgtcgtacccgcatccgcggtcg
atgccggacttctgggagttcccgacggtctccatgggcctcggtccgatcggcgcgatc
ttccaggcgcggatgaaccgctacatgcacgcgcgcgggatcgcggacacctcgaagtcg
cacgtgtgggccttcctcggcgacggcgagatggacgagccggagtcgctgggccagttg
tccatcgccgcccgggagggcctggacaacctgaccttcgtggtcaactgcaacctccag
cgcctggacggcccggtacgcggcaacggcaagatcatccaggagctggagtcggtcttc
cggggcgccggctggaacgtgatcaagctggtctgggaccggacctgggacccgctgctg
gcccaggaccgcgacggcgtgctggtcaaccgcatgaacacgacgccggacggccagttc
cagacgtacgccaccgagtccggcgcctacatccgcgaccacttcttcggcgacgaccac
cggctgcgcgcgatggtcgagaacatgaccgacgaccagatcctgcacctgggccgcggc
ggtcacgaccaccgcaagatctacgcggcgtacaaggcggcgctggagcacaagggccag
ccgacggtcatcctggccaagacgatcaagggctggacgctgggcccgaacttcgagggc
cgcaacgccacgcaccagatgaagaagctgacggtcgacgacctgaagcgcttccgcgac
cggctgcacctgccgatctccgacaaggagctggagtccggcccgccgccgtactaccac
ccgggccgggacacggaggagatgcagtacatgcacgaccggcgcctgggctgcggcgga
tacgtgccgacccgggtcgtgcggtcgaagccgctcgcgctgccggacgacaagacgtac
gcgaccgtgaagaaggggtcgggccagcagtccatcgcgacgacgatggcctttgtgcgc
ctgttgaaagacctcatgcgggacaaggagatcggcaggcggttcgtgctgatcgcgccg
gacgagtaccgcacgttcggcatggactcgttcttcccgagcgcgaagatctacaacccg
ctcggccagcagtacgagtcggtggaccgcgatctgctgctcgcctacaaggaggcgccg
aacgggcagatgctgcacgacggcatctcggaggcgggctgcacggcctcgctgatcgcg
gcgggctcggcctacgccacgcacggcgagccgctcatcccggtgtacgtcttctactcg
atgttcggattccagcgcaccggtgaccagttctggcagatgggtgaccagctggcgcgt
ggtttcgtgctgggcgcgaccgccggccgtacgacgctgaccggtgagggcctccagcac
gcggacggacactcgcagttgctggcctcgaccaacccggcgtgcgtggcgtacgacccc
gccttcgggttcgagatcgcgcacatcgtcaaggacgggctgcgccggatgtacggcggc
gacgaacagcacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagccc
atccggcacccggccgagcccgagaacgtggacgtcgagggcatcctcaagggcgtctac
cgcttcagcgagggcaccggcggctcgatcccggcacagatcatggcgtccggcgtagcg
gtgccgtgggccgtggaggcgcagcggatcctcgccgaggagtggaacgtgcgcgccgac
gtctggtcggcgacctcctggaacgagctgcggcgcgaggccgtggcctgcgaggagcac
aacctgctgcatcctgaggaggagcagcgggtgccctgggtcacgcggaagctggcgggg
gctcaggggccgttcgtggcggtgtccgactggatgcggtcggtgccggaccagatcgcg
cggtgggtgccggggacgtaccagtcgctgggcgcggacgggttcggcttcgcggacacc
cggggtgcggcgcgccggttcttccacatcgacgcgcagtcgatcgtggtgggcgtgctg
agcgagctggcccgggaggggaaggtcgaccggtcggtgctgaagcaggcgatcgaccgg
taccggctgctcgacgtgaccgcggccgacccgggggcggccggcggggacgcctag
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