Streptomyces coelicolor: SCO5281
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Entry
SCO5281 CDS
T00085
Symbol
SCCB12.05c
Name
(GenBank) putative 2-oxoglutarate dehydrogenase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sco
Streptomyces coelicolor
Pathway
sco00020
Citrate cycle (TCA cycle)
sco00630
Glyoxylate and dicarboxylate metabolism
sco00785
Lipoic acid metabolism
sco01100
Metabolic pathways
sco01110
Biosynthesis of secondary metabolites
sco01120
Microbial metabolism in diverse environments
sco01200
Carbon metabolism
sco01210
2-Oxocarboxylic acid metabolism
Module
sco_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sco_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sco00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SCO5281 (SCCB12.05c)
00630 Glyoxylate and dicarboxylate metabolism
SCO5281 (SCCB12.05c)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SCO5281 (SCCB12.05c)
Enzymes [BR:
sco01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SCO5281 (SCCB12.05c)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SCO5281 (SCCB12.05c)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SCO5281 (SCCB12.05c)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SCO5281 (SCCB12.05c)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Trypco1
Motif
Other DBs
NCBI-ProteinID:
CAC04496
Kitasato:
SCO5281
UniProt:
Q9FBR4
LinkDB
All DBs
Position
complement(5749846..5753664)
Genome browser
AA seq
1272 aa
AA seq
DB search
MSPQSPSNSSISTDTDQAGTAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFAD
YKPGAAATPTAAGTVPTDAGSTPPAAPAPRAQAPAQPQAAAPAPAPAKPAAAAPAAPAAP
ATKPAAAPAKPAAKPQAKAAAPAKDAGAAPEGPELVTLRGPAAAVAKNMNASLELPTATS
VRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPTMNHSFGEKDGKPT
LVKPAHINLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDNKLTMDD
FTGVTVSLTNPGGLGTVHSVPRLMPGQSVILGVGSMDYPAEFQGTSQDTLNKLGISKVMT
LTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDDIFKALRIPYEPVRWLKDIDASHDDD
VTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGGFAG
KSLMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRIERSHTKPEREEQLRILRRL
NAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVL
ANVVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLE
AVDPVLEGVSRAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGT
VHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAF
NKDVVIDLICYRRRGHNETDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQ
ALQDYQGQLEKVFTEVREAVSQPASAEPSEPQAEFPVAVNTAITAETVKRIAESQVNIPD
HITVHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLDGVPVRLTGQDSQRGTFGQRH
AVVIDRETGDEFTPLLYLSEDQARYNVYNSLLSEYAVMGFEYGYSLARPDALVMWEAQFG
DFVNGAQTVVDEFISSAEQKWNQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMT
VAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDDS
VDPAAVKKVVFTAGKVYYDLDAERKKRGLTDTAIIRIERLYPLPGAELQAEIAKYPNAEK
YLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQA
EQEQLVREVFEA
NT seq
3819 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcgggcacc
gcgggaaagaaccccgcggccgcgttcggtgccaatgagtggctcgtcgacgagatctat
cagcagtacctccaggacccgaactccgtggaccgagcctggtgggacttcttcgccgac
tacaagcccggagcggcggcgaccccgaccgccgccggcaccgtgcccacggacgccggc
agcacgccaccggccgcccccgccccgcgggcgcaggccccggcgcagccgcaggccgcc
gccccggcgcccgcccccgcgaagcccgccgccgccgcccccgcggctccggccgctccg
gccaccaagcccgccgccgcgccggccaagccggccgccaagccgcaggcgaaggccgcc
gcgcccgccaaggacgccggcgccgcccccgagggccccgagctggtgaccctgcgcggc
ccggccgccgcggtcgcgaagaacatgaacgcctcgctggagctgcccacggccacgtcc
gtgcgcgcggtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctc
aagcgcgcccggggcgggaagatctccttcacgcacctgatcggctacgcgatggtgcag
gccatcaaggccatgccgacgatgaaccactcgttcggcgagaaggacggcaagccgacc
ctggtcaagccggcccacatcaacctcggcctcgccatcgacctggtcaagcccaacggc
gaccgccagctggtcgtcgcggcgatcaagaaggccgagacgctgaacttcttcgagttc
tggcaggcctacgaggacatcgtccgtcgcgcccgcgacaacaagctgacgatggacgac
ttcaccggcgtcacggtctccctgaccaaccccggcggcctcggcaccgtccactccgtg
ccgcgcctgatgcccggccagtcggtcatcctgggcgtcggctccatggactacccggcg
gagttccagggcaccagccaggacaccctgaacaagctcggcatctcgaaggtcatgacg
ctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcgc
caggtcgccaacctgctgctgggcgagaacggcttctacgacgacatcttcaaggcgctg
cgcatcccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgacgac
gtcaccaaggccgcccgcgtcttcgagctgatccactcctaccgggtgcgcggccacgtc
atggccgacaccgacccgctggagtaccagcagcgcaagcaccccgacctggacatcacc
gagcacgggctcaccctgtgggacctggagcgcgagttcgcggtcggcggcttcgccggc
aagtccctgatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcacc
accggcgtcgagttcatgcacatccaggacccgaagcagcgcaagtggatccaggaccgc
atcgagcgctcgcacaccaagccggagcgcgaggagcagctgcgcatcctgcgccggctg
aacgccgccgaggcgttcgagaccttcctccagaccaagtacgtcggccagaagcggttc
tccctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactcggcggcc
gagtcccgcctggacgaggtcgtcatcggcatggcccaccgcggccggctgaacgtgctg
gccaacgtggtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaatctcgac
ccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttc
accggtctggacggcgagcagatcaaggtctcgctggtcgccaacccctcgcacctggag
gcggtggacccggtcctggagggcgtctcgcgcgccaagcaggacatcatcaacaagggc
ggcacggacttcacggtcctgccggtggcgatccacggcgacgcggccttcgcgggccag
ggcgtggtggccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggcacg
gtccacgtcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcctcgcgctcc
tcgatgtacgccaccgacgtggcccgcatgatcgaggccccgatcttccacgtgaacggc
gacgaccccgaggccgtcgtccgcgttgcccggctggccttcgagttccgccaggcgttc
aacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagaccgac
aacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgc
aagctgtacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggccgagcag
gcgctccaggactaccagggccagctggagaaggtcttcaccgaggtccgcgaggccgtc
tcgcagccggcgtcggcggagccctcggagccgcaggcggagttcccggtcgccgtgaac
accgcgatcaccgccgagaccgtcaagcgcatcgccgagtcccaggtcaacatccccgac
cacatcaccgtgcacccgcggctgctgccgcagttgcagcgccgcgcggcgatggtcgag
gacggcacgatcgactggggcatgggcgagaccctcgccgtcggctccctcctgctggac
ggcgtgccggtccggctgaccggccaggactcgcagcgcggcaccttcggccagcgccac
gcggtcgtcatcgaccgtgagacgggcgacgagttcaccccgctgctgtacctgtccgag
gaccaggcccggtacaacgtctacaactccctcctctccgagtacgcggtgatgggcttc
gagtacggctactcgctggcccgcccggacgcgctggtgatgtgggaggcgcagttcggc
gacttcgtcaacggcgcgcagacggtcgtggacgagttcatctcgtcggccgagcagaag
tggaaccagacctccggcgtcaccctgctcctgccgcacggctacgagggccagggcccg
gaccactcctcggcccgcccggagcgcttcctccagctgtgcgcgcagaacaacatgacg
gtcgcgatgccgaccctgccgtcgaactacttccacctcctgcggtggcaggtgcacaac
ccgcaccacaagccgctggtggtcttcaccccgaagtcgatgctgcgcctcaaggcggcg
gcctcgaaggcggaggagttcacgacgggccagttccgcccggtcatcggcgacgactcg
gtcgacccggccgccgtcaagaaggtcgtcttcacggccggcaaggtctactacgacctc
gacgccgagcggaagaagcgcggcctgacggacacggccatcatccgcatcgagcgcctg
tacccgctgccgggtgccgagctccaggcggagatcgccaagtacccgaacgccgagaag
tacctgtgggcccaggaggagccggcgaaccagggcgcttggccgttcatcgcgctcaac
ctgatcgaccacctggacctggcggtcggcgccgacgtcccgcacggcgagcgcctgcgc
cgcatctcgcggccgcacggctcgtccccggccgtcggttccgccaagcggcaccaggcc
gagcaggagcagctggtgcgtgaggtgttcgaggcgtga
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