KEGG   Streptomyces coeruleorubidus: CP976_09370
Entry
CP976_09370       CDS       T07302                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
scoe  Streptomyces coeruleorubidus
Pathway
scoe00270  Cysteine and methionine metabolism
scoe00450  Selenocompound metabolism
scoe00670  One carbon pool by folate
scoe01100  Metabolic pathways
scoe01110  Biosynthesis of secondary metabolites
scoe01230  Biosynthesis of amino acids
scoe04980  Cobalamin transport and metabolism
scoe04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:scoe00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CP976_09370 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CP976_09370 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CP976_09370 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    CP976_09370 (metH)
   04980 Cobalamin transport and metabolism
    CP976_09370 (metH)
Enzymes [BR:scoe01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CP976_09370 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: QEV24339
UniProt: A0A5J6HVF5
LinkDB
Position
complement(1991445..1994966)
AA seq 1173 aa
MASLPPTPSADSRTRVSALREALATRVVVADGAMGTMLQAQDPTLEDFENLEGCNEILNV
TRPDIVRSVHDAYFAVGVDCVETNTFGANHTAAAEYEISDRVHELSEAGARIAREVADEY
AAGDGRQRWVLGSIGPGTKLPTLGHVTYSLIRDGYQANAEGLLAGGADALLVETTQDLLQ
TKASILGARRAMEATGVEVPLLCSMAFETTGTMLLGSEIGAALTALEPLGIDMIGLNCST
GPAEMSEHLRYLTRHSRIPLLCMPNAGLPILTKDGAHFPLDPEGLADAQQNFVRDYGLSL
VGGCCGTTPEHLRQLVERVREATPTERSPQPEPGAASLYQSVPFRQDTAYLAIGERTNAN
GSKKFREAMLEGRWDDCVEMAREQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTL
PIVLDSTEVEVIRAGLEKLGGRAVINSVNYEDGDGPESRFAKVTQLAREHGAALIALTID
EEGQARTAEKKVEIAERLIEDLTGNWGIHEEDILVDCLTFTICTGQEESRKDGIATIEGI
RELKRRHPKVQTTLGLSNISFGLNPAARMLLNSVFLDECVKAGLDSAIVHASKILPIARF
SEEEVQTALDLIYDRRAEGYDPLQKLMQLFEGATAKSLKAGKAEELAALPLDERLKRRII
DGERNGLEADLDEALESRPALDIVNETLLEGMKVVGELFGSGQMQLPFVLQSAEVMKTAV
AHLEPHMEKVEGDEAGKGTIVLATVRGDVHDIGKNLVDIILTNNGYNVVNLGIKQPVSAI
LEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRDLAAKYPVILGGAALTRAYVEQDLH
EIYQGEVRYARDAFEGLRLMDALIGVKRGVPGAKLPELKQRRVRATAQAAVEERPEEGHV
RSDVAIDNPVPEPPFRGTRVIKGIQLKEYASWLDEGALFKGQWGLKQARTGEGPSYEELV
ETEGRPRLRGLLDKLQTENLLEAAVVYGYFPCVSKDDDLIILDEQGNERTRFTFPRQRRG
RRLCLADFFRPEESGETDVVGLQVVTVGSRIGEETARLFESNAYRDYLELHGLSVQLAEA
LAEYWHARVRSELGFAGEDPDEMQGMFELKYRGARFSLGYGACPNLEDRAKIADLLQPER
IGVHLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3522 nt   +upstreamnt  +downstreamnt
atggcctcgttgccaccgaccccttccgcagacagccggacccgcgtgtccgccctccga
gaggccctggccacccgcgtggtcgtggccgacggagccatgggcaccatgctccaggcc
caggacccgacgctcgaggacttcgagaatctcgaaggctgtaacgagatcctcaacgtg
acccggccggacatcgtccgttccgtccacgacgcgtacttcgcggtcggcgtcgactgc
gtcgagaccaacacgttcggcgccaaccacacggccgcggccgagtacgagatctccgac
cgggtgcacgagctgtccgaggcgggtgcccggatcgcccgcgaggtggccgacgagtac
gccgccggagacggccggcagcgctgggtgctcggctcgatcggccctggcaccaagctg
cccacgctcggccacgtcacctacagcctcatccgcgacggctaccaggccaacgccgag
ggcctgctcgccggcggcgcggacgcgctgctcgtggagaccacgcaggacctgctccag
acgaaggcctccatcctcggcgcccgccgggccatggaggccaccggcgtcgaggtgccc
ctgctgtgctcgatggccttcgagaccaccggcaccatgctgctgggctccgagatcggc
gcggcgctgaccgcgctggagccgctcggcatcgacatgatcgggctgaactgctccacc
ggcccggccgagatgagcgagcacctgcgctatctgacgcgccactcgcgcatcccgctg
ctgtgcatgccgaacgccggcctgccgatcctcaccaaggacggcgcccacttcccgctc
gaccccgagggcctggccgacgcccagcagaacttcgtccgcgactacggcctgtccctg
gtcggcggctgctgcggcaccacccccgagcacctgcgccagctcgtcgagcgcgtccgg
gaggccaccccgaccgagcgcagcccgcagcccgagccgggtgcggcgtcgctgtaccag
tcggtgccgttccggcaggacaccgcgtacctggcgatcggtgagcggacgaacgccaac
gggtcgaagaagttccgtgaggccatgctggagggccgctgggacgactgtgtggagatg
gcccgggagcagatccgtgagggcgcgcacatgctcgatctgtgcgtggactatgtcggc
cgggacggtgtggccgacatggaggagctggccgggcgtttcgccaccgcttcgacgctg
ccgatcgtgctggactccaccgaggtggaggtgatccgagccggtctggagaagctcggc
ggccgggcggtgatcaactcggtgaactacgaggacggtgacggtccggagtcgcgcttc
gcgaaggtcacgcagctggcgcgggagcatggtgccgcgctgatcgcgttgacgatcgac
gaggagggccaggcccgcacggccgagaagaaggtcgagatcgccgagcggctgatcgag
gacctgaccgggaactggggcatccacgaggaggacatcctcgtggactgtctgacgttc
acgatctgcaccggtcaggaggagtcccgcaaggacggcatcgccacgatcgagggcatc
cgcgagttgaagcggcgtcatccgaaggtgcagacgacgctgggtctgtcgaacatctcc
ttcggtctgaacccggccgcgcggatgctgctgaactcggtgttcctggacgagtgtgtg
aaggcgggcctcgactcggcgatcgtgcacgcgagcaagatcctgccgatcgcccgtttc
agcgaggaggaggtccagacggctctggacctgatctacgaccgccgcgccgagggctac
gacccgctgcagaagctcatgcagctgttcgagggtgcgacggccaagtccctcaaggcc
ggcaaggccgaggaactggccgcgctgccgctggacgagcgcctcaagcggcgcatcatc
gacggcgagcgcaacggcctcgaagccgacctggacgaggcgctcgagtcccggccggcc
ctggacatcgtcaacgagacgctgctggagggcatgaaggtcgtcggtgagctgttcggc
tccggtcagatgcagctgccgttcgtgctccagtcggccgaggtgatgaagacggccgtg
gcccatctcgaaccgcacatggagaaggtcgagggcgacgaggccggcaagggcacgatc
gtgctggccaccgtgcgcggcgatgtgcacgacattggcaagaacctggtcgacatcatc
ctgacgaacaacggctacaacgtcgtcaacctcggcatcaagcagccggtctcggcgatc
cttgaggccgccgaggagcacagggccgatgtgatcggcatgtccgggctgctggtcaag
tccacggtgatcatgaaggagaacctggaggagctgaaccagcgcgacctggcggcgaag
tacccggtcatcctgggcggtgccgccctcacccgcgcctatgtcgagcaggacctgcac
gagatctaccagggcgaggtccgctacgcccgcgacgccttcgagggactgcgcctgatg
gacgccctgatcggcgtcaagcggggtgtgcccggcgcgaagctgcccgagctgaagcag
cgccgggtccgggccaccgcccaggccgccgtggaggagcgccccgaggaggggcacgtc
cgctccgacgtcgccatcgacaaccccgtgcccgagccgcccttccgcgggacccgcgtg
atcaagggcatccagctcaaggagtacgcgagctggctcgacgagggcgccctgttcaag
ggccagtggggcctcaagcaggcccgcaccggcgagggcccgtcgtacgaggaactggtc
gagaccgagggccggccccggctgcgcgggctgctggacaagctccagacggagaacctg
ctggaggcggccgtggtctacggctacttcccgtgcgtctccaaggacgacgacctgatc
atcctggacgagcagggcaacgagcgcacccgcttcaccttcccgcgccagcgccgcggc
cggcgcctgtgcctggccgacttcttccgcccggaggagtccggcgagacggacgtcgtg
ggcctccaggtcgtcaccgtcggctcgcgcatcggcgaggagaccgcgcgtctgttcgag
tccaacgcctaccgcgactacctcgaactgcacggcctgtccgtgcagttggccgaggcg
ctcgccgagtactggcacgcgcgcgtgcgctccgaactcggcttcgccggtgaggacccg
gacgagatgcagggcatgttcgagctgaagtaccggggcgcccgcttctccctcggctac
ggcgcctgccccaacctggaggaccgcgccaagatcgcggacctgctccagccggagcgc
atcggcgtccacctgtccgaggagttccagctccaccccgagcagtccacggacgccatc
gtgatccaccacccggaggcgaagtacttcaacgcccgctga

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