Streptomyces coeruleorubidus: CP976_12620
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Entry
CP976_12620 CDS
T07302
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
scoe
Streptomyces coeruleorubidus
Pathway
scoe00010
Glycolysis / Gluconeogenesis
scoe00020
Citrate cycle (TCA cycle)
scoe00620
Pyruvate metabolism
scoe00785
Lipoic acid metabolism
scoe01100
Metabolic pathways
scoe01110
Biosynthesis of secondary metabolites
scoe01120
Microbial metabolism in diverse environments
scoe01200
Carbon metabolism
scoe01210
2-Oxocarboxylic acid metabolism
Module
scoe_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
scoe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP976_12620 (aceE)
00020 Citrate cycle (TCA cycle)
CP976_12620 (aceE)
00620 Pyruvate metabolism
CP976_12620 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP976_12620 (aceE)
Enzymes [BR:
scoe01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP976_12620 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
QEV24930
UniProt:
A0A5J6I2X1
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All DBs
Position
2710242..2712944
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AA seq
900 aa
AA seq
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MTDPNAIQPSELDQLPDRDPEETAEWQASLDAVTEAAGPHRAAYLMRRTLERAEGAGIAL
PKLLETDYVNSIPTAAEPAVPGDEAMEQRITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFKGKEADGSGDQLYIQGHASPGIYARAFLDGRLNEEQLDNFRRESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDTSASHVWAFLGDGEM
DEPESTAALALAAREELDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVIKTL
WGTAWDELFRLDTTGALVRRLRQVPDAQIQTYQTRDAAYIRQDFFGGDPALAEMAKLLSD
DKILECFHFSRGGHEARKVYAAYKAAVEHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLTVDEFKNMRDLLGLPIKDSDFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
PVAPLPAPAEKAFASFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEARNGQILNEGITEAGSMADFIAASTSYAT
HGETMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEVAAIVKEGLRRMYGEAAPGEDQNVFYYLTVYNEPLPQPAKPS
VDGIDEGIVKGLYRFNTAESAGITPPANAPRIQLLGSGTAIHWALKAQQLLAEEWGVAAD
VWSATSWSELRRDALEADEALLRGEERMPFVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDWSSLGADGFGLSDTREAARRHFGVDAESIVVAALAQLAKRGEVKATAVKEARAKYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgagctcgaccagctcccggaccgggacccg
gaggagaccgccgaatggcaggcctccctggacgcggtgaccgaggcggccgggccgcac
cgtgccgcgtatctgatgcggcgcacgctggagcgcgccgagggcgccggcatcgcgctg
ccgaagctcctggagacggactacgtcaactccatccccaccgccgccgagccggccgtg
cccggtgacgaggcgatggagcagcggatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacccggggcagcaagtacggcgtcggcggccacatcgccaccttcgcctccgcc
gcctggctgtacgagaccggcttcaaccacttcttcaaaggcaaggaggccgacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgcgttcctc
gacggccgtctgaacgaggagcaactcgacaacttccgccgcgagtcgggcggcaacggc
ctgccctcctacccgcacccgcgccgactgccctggctgtgggagttcccgaccgtctcc
atgggtctgggcccgctctccgccatctaccaggcgcgcttcaaccgctacctcaccaac
cgcggcatcaaggacacctccgcctcgcacgtgtgggcgttcctcggtgacggcgagatg
gacgagcccgagtcgacggcggccctcgcgctggcggcccgtgaggagctggacaacctc
acgttcgtcatcaactgcaacctccagcgcctcgacggcccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcatcaagacgctg
tggggcacggcctgggacgagctgttccggctggacaccacgggcgcgctcgtacgccgc
ctgcgccaggtaccggacgcgcagatccagacgtaccagacccgcgacgccgcctacatc
cgccaggacttcttcggcggcgacccggcgctggcggagatggcgaagctgctgagcgac
gacaagatcctcgagtgcttccacttctcgcgcggcggtcacgaggcgcgcaaggtgtac
gccgcgtacaaggcggccgtcgagcacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaagaacatgcgcgacctgctcggcctgccgatcaaggac
agcgacttcgtcgacggcgtggtgccctacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcggcgtgccgccctcggcggtccggccccggcccgccgcgtccac
ccggtcgcgccgctgcccgccccggcggagaaggcgttcgcctccttcgacaagggctcc
ggctcgcagaacgtggccaccaccatggcgttcgtccgcctggtgaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtcccggacgaggcgcgcaccttcggt
atggagagcctcttcccgtccctgggcatctactcgcccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggcccgcaacggccagatcctcaacgag
gggatcaccgaggccggttcgatggccgacttcatcgccgcttcgacgtcgtacgcgacg
cacggcgagacgatgatcccgttctacatcttctactccatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctcggccgcggtttcctcgtgggcgccacg
gcgggccgtacgacgctgaccggtgagggcctccagcacgccgacggccactcccccgtc
atcgccgcgacgaacccggcggcgctgacgtacgacccggcgttcgcgtacgaggtcgcg
gccatcgtcaaggagggcctgcgccggatgtacggcgaggcggccccgggtgaggaccag
aacgtcttctactacctgaccgtctacaacgagccgctgccgcagcccgcgaagccgtcc
gtcgacggcatcgacgagggcatcgtcaagggcctgtaccgcttcaacacggcggagtcg
gcgggcatcacgcccccggccaacgccccgcggatccagctgctcggctccggtacggcg
atccactgggcgctcaaggcccagcagctccttgccgaggagtggggcgtggcggccgac
gtctggtcggcgacctcgtggagcgagctgcgccgggacgccctggaggcggacgaggcg
ctgctgcgcggcgaggagcggatgccgttcgtccggcaggcgctccagggcgccgagggc
ccggtgctggcggtctccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactggtcctcgctgggcgccgacggcttcggcctctcggacacccgcgaggcg
gcccgccgccacttcggcgtcgacgccgagtcgatcgtcgtcgcggccctggcccagctc
gccaagcgcggcgaggtcaaggccacggccgtgaaggaagcgcgcgcgaagtacggtctg
taa
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