Streptomyces coeruleorubidus: CP976_29020
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Entry
CP976_29020 CDS
T07302
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scoe
Streptomyces coeruleorubidus
Pathway
scoe00020
Citrate cycle (TCA cycle)
scoe00630
Glyoxylate and dicarboxylate metabolism
scoe00785
Lipoic acid metabolism
scoe01100
Metabolic pathways
scoe01110
Biosynthesis of secondary metabolites
scoe01120
Microbial metabolism in diverse environments
scoe01200
Carbon metabolism
scoe01210
2-Oxocarboxylic acid metabolism
Module
scoe_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scoe_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scoe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CP976_29020
00630 Glyoxylate and dicarboxylate metabolism
CP976_29020
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP976_29020
Enzymes [BR:
scoe01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CP976_29020
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CP976_29020
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CP976_29020
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CP976_29020
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QEV27755
UniProt:
A0A5J6IGF0
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All DBs
Position
complement(6238297..6242118)
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AA seq
1273 aa
AA seq
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MSPQSPSNSSISTDTDQAGKNPAASFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAASAPAGTAAAGAAGTTTAQPAAQAAPAQAAAPAPAAQQPAAAAPAPAPAKPAAQAP
AQAPAPAKAAPAAAKPAAAAKPKAEPAGEAPSGPEQVVLRGPAAAVAKNMDASLELPTAT
SVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPAMNYAFAKVDGKP
TLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMD
DFSGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVM
TLTSTYDHRVIQGAASGEFLRQVANLLLGENNFYDEIFEALRIPYEPVRWLKDIDASHDD
DVTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGGFA
GKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHSKPEREEQLRILRR
LNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVVGMAHRGRLNV
LANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHL
EAVDPVLEGVSRAKQDIIGKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGG
TVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQA
FNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAE
QALQDYQGQLEKVFTEVREATSQPAAAEPTDPQAEFPVAVNTAVTTEVVKRIAESQVNIP
DHITVHPRLLPQLQRRASMVEDGTIDWGMGETLAVGSLLLEGVPVRLAGQDSQRGTFGQR
HAVIIDRSTGDEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPEALVMWEAQF
GDFVNGAQTVVDEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQMCAQNNM
TVAMPTSPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFQPVIGDA
SVDAAAVKKVVFCAGKVYYDLEAERQKRGVTDTAIIRIERLYPLPGAELQAEIKKYPNAE
KYLWAQEEPANQGSWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQ
AEQEQLVREVFDA
NT seq
3822 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcggggaag
aaccctgccgcgtcgttcggtgccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggggcggctgccgcctcggctccggcgggtaccgcggccgcgggggccgcggggaccacc
accgctcagccggcggcccaggccgcccccgcccaggccgcggcccccgccccggcggcc
cagcagcccgcggccgccgcgccggctcccgctccggcgaagcccgccgcgcaggccccg
gctcaggctcccgctccggcgaaggcggctccggccgccgccaagccggccgccgccgcg
aagccgaaggccgagcccgccggcgaagccccctcgggtcccgagcaggtcgtgctgcgc
ggccccgccgccgcggtcgcgaagaacatggacgcctccctggagctgcccacggccacg
tccgtgcgcgcggtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccac
ctcaagcgggcgcgcggcgggaagatctccttcacgcacctcatcggctacgcgatggtc
caggccatcaaggcgatgccggcgatgaactacgcgttcgcgaaggtggacggcaagccg
accctggtcaagccggagcacgtcaacctcggcctcgccatcgacctggtcaagccgaac
ggcgaccgccagctggtcgtcgcggcgatcaagaaggccgagacgctgaacttcttcgag
ttctggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaagctgacgatggac
gacttctccggggtcacggtctccctgaccaaccccggcggcctcggcacggtccactcg
gtgccgcgtctgatgcccggccagtccgtgatcatgggcgtcggctccatggactacccg
gcggagttccagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatg
acgctcacgtcgacctacgaccaccgggtgatccagggcgccgcctccggcgagttcctg
cgccaggtcgcgaacctcctgctcggcgagaacaacttctacgacgagatcttcgaggcg
ctgcgcatcccctacgagccggtccgctggctcaaggacatcgacgcgagccacgacgac
gacgtcacgaaggccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccac
gtcatggccgacaccgacccgctggagtaccagcagcgcaagcaccccgacctggacatc
accgagcacggcctcacgctctgggacctggagcgcgagttcgccgtcggcggcttcgcc
ggcaagtcgatgatgaagctgcgcgacatcctcggcgtcctgcgcgactcgtactgccgc
accaccggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggatccaggac
cgtgtggagcgcccgcactccaagccggagcgcgaggagcagctgcgcatcctgcgccgt
ctgaacgcggccgaggccttcgagacgttcctccagaccaagtacgtcggccagaagcgc
ttctccctggagggcggcgagtccgtcatcccgctgctggacgcggtcctcgacagcgct
gcggagtcccgcctggacgaggtcgtcgtcggcatggcccaccgcggccgtctgaacgtc
ctggccaacatcgtcggcaagtcgtacgcccagatcttccgcgagttcgagggcaacctc
gacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcacc
ttcacgggcctcgacggcgagcagatcaaggtcagcctggtcgcgaacccgtcgcacctc
gaagccgtcgacccggtcctggaaggcgtctcccgcgccaagcaggacatcatcggcaag
ggcggcacggacttcacggtcctgccggtggcgatccacggcgacgcggccttcgcgggc
cagggcgtggtggccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggc
acggtccacatcgtcatcaacaaccaggtcggcttcaccgcggcccccgagtcctcgcgt
tcctccatgtacgcgacggacgtggcccgcatgatcgaggccccgatcttccacgtgaac
ggtgacgacccggaggccgtggtccgcgtggcccggctggccttcgagttccgccaggcg
ttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcg
gacaacccggccttcacccagcccctgatgtacgacctgatcgacaagaagcgctcggtg
cgcaagctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggccgag
caggcgctccaggactaccagggccagctcgagaaggtcttcacggaggtccgcgaggcc
acctcgcagccggccgccgcggagcccaccgacccgcaggccgagttcccggtcgccgtg
aacaccgcggtgaccacggaggtcgtcaagcggatcgccgagtcccaggtcaacatcccc
gaccacatcaccgtccacccgcgtctgctgccgcagctccagcgccgggcgtcgatggtc
gaggacggcacgatcgactggggcatgggcgagaccctcgcggtcggctccctcctcctg
gagggcgtcccggtccgcctggccggccaggactcgcagcgcggtacgttcggccagcgc
cacgcggtcatcatcgaccgcagcacgggcgacgagtacacgccgctgcagtacctctcc
gaggaccaggcgcgtctgaacgtctacaactccctcctctccgagtacgcggcgatgggc
ttcgagtacggctactcgctggcccgccccgaggcgctcgtgatgtgggaggcgcagttc
ggcgacttcgtcaacggcgcgcagacggtcgtggacgagttcatctcgtcggccgagcag
aagtgggcccagacctccggtgtggtcctgctcctcccgcacggctacgagggccagggc
ccggaccactcgtccgcccgcccggagcgcttcctccagatgtgcgcccagaacaacatg
acggtcgccatgccgacgtcgccgtcgaactacttccacctcctgcggtggcaggtgcac
aacccgcaccacaagccgctggtggtcttcactccgaagtcgatgctgcgtctgaaggcg
gcggcctcgaaggcggaggagttcacgaccggccagttccagccggtcatcggcgacgcg
tcggtggacgcggccgcggtcaagaaggtcgtcttctgcgccggcaaggtctactacgac
ctggaggccgagcgtcagaagcgcggcgtcacggacacggcgatcatccgcatcgagcgc
ctgtacccgctgccgggtgccgagctccaggcggagatcaagaagtacccgaacgccgag
aagtacctgtgggcccaggaggagccggcgaaccagggttcctggccgttcatcgcgctc
aacctgatcgaccacctggacctggcggtcggcgcggacgtcccgcacggcgagcgactg
cgccgcatctcgcgcccgcacagctcgtccccggcagtgggttccgcgaagcggcaccag
gccgagcaggagcagctggtgcgtgaggtgttcgacgcgtaa
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