KEGG   Streptomyces coeruleorubidus: CP976_30305
Entry
CP976_30305       CDS       T07302                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
scoe  Streptomyces coeruleorubidus
Pathway
scoe03030  DNA replication
scoe03410  Base excision repair
scoe03420  Nucleotide excision repair
scoe03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:scoe00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    CP976_30305 (ligA)
   03410 Base excision repair
    CP976_30305 (ligA)
   03420 Nucleotide excision repair
    CP976_30305 (ligA)
   03430 Mismatch repair
    CP976_30305 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:scoe03032]
    CP976_30305 (ligA)
   03400 DNA repair and recombination proteins [BR:scoe03400]
    CP976_30305 (ligA)
Enzymes [BR:scoe01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     CP976_30305 (ligA)
DNA replication proteins [BR:scoe03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     CP976_30305 (ligA)
DNA repair and recombination proteins [BR:scoe03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     CP976_30305 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     CP976_30305 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     CP976_30305 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      CP976_30305 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT Nlig-Ia HHH_5 Zn_ribbon_TFIIB
Other DBs
NCBI-ProteinID: QEV27985
UniProt: A0A5J6IH35
LinkDB
Position
6521486..6523681
AA seq 731 aa
MAGDKQAETTTVPAEAREKHARLAEQIEEHRFRYYVKDAPVVSDAEFDELLRSLEALEEE
FPELRTPDSPTQKVAGSYETEFTAVEHRQRMLSLDNTFNDEEMAAWTERIARELGEQDYH
FLCELKVDGLAVNLTYERGRLTRAATRGDGRTGEDITPNVRTIAEIPERLKGDSVPDLVE
IRGEVYFPMEKFQELNARLVEAGDKPFANPRNAAAGSLRQKDPRVTATRPLHMVVHGIGA
LEGFSGLTRLSQAYDLLKTWGLPTSRHNKVVDGLDGVREFIAYFGENRHSVEHEIDGVVV
KLDEIPLQGRLGSTSRAPRWAIAYKYAPEEVNTKLVNIRVGVGRTGRVTPYAQVEPVTVA
GSEVEFATLHNQDVVKAKGVLIGDTVVLRKAGDVIPEILGPVADLRDGSEREFVMPAECP
ECGTALRPMKEGDVDLRCPNARTCPAQLRERLFYLAGRKALDIEHFGYVAAAALTKPLEP
EDPPLVDEGDLFDLTVEQLLPIKAYVLDADSGLPKRDPKTGEEKVATIFANQEGQPRKNA
LAMLENIAAAKQRPLARIITSLSIRHVGPVAAEALAREFRSIERIDQATEEELAVTEGVG
PTIAASLKQWFAEDWHREIIRKWKAAGVRMEEESTGEDEGPRPLEGLTVVVTGTLEHFTR
DGAKEALQSRGAKVTGSVSKKTSFVVVGDSPGSKYDKAMQLKVPVLNEEGFGVLLEQGPD
AAAEVALSAEE
NT seq 2196 nt   +upstreamnt  +downstreamnt
gtggccggcgacaagcaagcggagacgacgacggtgcccgccgaggcacgggagaagcac
gcgcgcctcgcggagcagatcgaagagcaccgcttccgctactacgtgaaggacgctccc
gttgtcagcgacgcggagttcgacgagctgctgcgttccctggaggcactggaggaggag
ttcccggagctgcgtaccccggactcgccgacccagaaggtcgccggttcgtacgagacg
gagttcacggcggtcgagcaccgccagcgcatgctctccctcgacaacaccttcaacgac
gaggagatggccgcctggacggagcgcatcgccagggaactgggcgagcaggactaccac
ttcctgtgcgagctgaaggtcgacggcctcgccgtgaacctcacctacgagcgcggccgt
ctcacgcgcgcggcgacccgcggcgacggccgcacgggcgaggacatcacaccgaacgtc
cggacgatcgcggagatccccgagcgcctcaagggcgactccgtccccgacctcgtggag
atccgcggcgaggtctacttcccgatggagaagttccaggagctgaacgcccgtctggtc
gaggccggtgacaagccgttcgccaacccgcgcaacgcggcggccggttcactgcgccag
aaggacccgcgggtcacggccacccgcccgctgcacatggtggtccacggcatcggcgcc
ctggagggcttcagcggcctgacccgcctgtcccaggcctacgacctgctgaaaacctgg
ggtctgcccacctcccggcacaacaaggtggtcgacggcctcgacggcgtacgggagttc
atcgcgtacttcggcgagaaccgccactccgtggagcacgagatcgacggcgtggtcgtc
aagctcgacgagatcccgctccagggccgcctcggctccacctcgcgcgccccgcgctgg
gcgatcgcgtacaagtacgcgccggaggaggtcaacaccaagctcgtcaacatccgcgtg
ggcgtgggccgcacgggcagggtcacgccgtacgcccaggtcgagccggtcacggtcgcg
ggctccgaggtcgagttcgccacgctgcacaaccaggacgtggtcaaggccaagggcgtc
ctcatcggtgacacggtggtgctgcgcaaggccggtgacgtcatcccggagatcctcgga
ccggtcgccgacctgcgtgacggcagcgagcgcgagttcgtgatgccggccgagtgcccc
gagtgcggtacggctctcaggccgatgaaggagggcgacgtcgacctgcgctgcccgaac
gcccgcacctgcccggcccagttgcgcgagcgcctgttctacctcgcgggccgcaaggcg
ctggacatcgagcacttcggctacgtcgccgccgccgcgctcaccaagccgctggagccc
gaggacccgccgctggtggacgagggcgacctgttcgacctcaccgtcgaacagctcctg
cccatcaaggcgtacgtcctcgacgccgacagcggtctgcccaagcgcgacccgaagacc
ggcgaggagaaggtcgccacgatcttcgccaaccaggagggccagccccgcaagaacgcg
ctcgccatgctggagaacatcgctgcggccaagcagcgtcccctcgcccggatcatcacc
agcctgtcgatccgtcacgtcggaccggtcgccgccgaggcactggcccgcgagttccgc
tcgatcgagcgcatcgaccaggccacggaggaggagctggcggtcaccgagggcgtcggc
ccgaccatcgccgcctctctcaagcagtggttcgccgaggactggcaccgcgagatcatc
cgaaagtggaaggccgccggcgtccgcatggaggaggagagcaccggcgaggacgaggga
ccccgcccgctcgaagggctcaccgtcgtcgtcacgggcaccctcgaacacttcacgcgc
gacggcgccaaggaggccttgcagagccgcggagcgaaggtgaccggctcggtttcgaaa
aagacgtcattcgtcgttgtgggtgacagtcctggatcgaaatacgacaaggcgatgcag
ctgaaggtcccggtcctgaacgaggagggtttcggggtcctgctggagcagggaccggac
gcggcggcggaagtcgccctttcggccgaggagtag

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