Streptomyces cyaneochromogenes: EJ357_31235
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Entry
EJ357_31235 CDS
T06811
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scya
Streptomyces cyaneochromogenes
Pathway
scya00020
Citrate cycle (TCA cycle)
scya00630
Glyoxylate and dicarboxylate metabolism
scya00785
Lipoic acid metabolism
scya01100
Metabolic pathways
scya01110
Biosynthesis of secondary metabolites
scya01120
Microbial metabolism in diverse environments
scya01200
Carbon metabolism
scya01210
2-Oxocarboxylic acid metabolism
Module
scya_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scya_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scya00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
EJ357_31235
00630 Glyoxylate and dicarboxylate metabolism
EJ357_31235
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EJ357_31235
Enzymes [BR:
scya01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
EJ357_31235
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
EJ357_31235
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
EJ357_31235
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
EJ357_31235
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AZQ37373
UniProt:
A0A3Q9EWZ6
LinkDB
All DBs
Position
complement(6819894..6823682)
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AA seq
1262 aa
AA seq
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MSPQSPSNSSISTDADQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GVGAAAPAGTAAAGAAATTTAPAAPAAPAAPSVPAPAPAAPKPAAAAPAAAAPAPAAKPA
APAPAAKPAQPKKAEPAAAADGPELVTLRGPAAAVAKNMNASLEVPTATSVRAVPVKLLF
DNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKDGKPTLVKPEHINFG
LAIDLVKPNGERQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLGMDDFTGVTVSLTN
PGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVI
QGAASGEFLRIVANFLLGEGNFYDEIFEALRIPYEPVRWLKDIDASHDDDVTKAARVFEL
IHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSLMKLRDIL
GVLRDSYCRTTGIEFMHIQDPKQRKWIQDRIERGHTKPEREEQLRILRRLNAAEAFETFL
QTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQ
IFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLTANPSHLEAVDPVLEGVA
RAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVG
FTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLIC
YRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQGQLE
KVFTEVREATSQPAAVEPSDPQAEFPVAVNTAVTTETVKRIAESQVNIPDHITVHPRLLP
QLQRRASMVEDGTIDWGMGETLAIGSLLLEGVPVRLAGQDSQRGTFGQRHAVIIDRETGE
EYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVMWEAQFGDFVNGAQTVV
DEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTSPANY
FHLLRWQSHNPHHKPLVVFTPKSMLRLKAAASKAEEFTSGQFQPVIGDASVDPAAVKKVV
FCAGKVYYDIEAERKKRGITDTAIIRIERLYPLPGAELQAEIAKYPNAEKYLWAQEEPAN
QGAWPFIALNLIDHLDLAVGAEVPHGERLRRISRPHGSSPAVGSAKRHQAEQEQLVREVF
EA
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacgccgaccaagcgggcaag
aaccccgctgccgcgttcggcccgaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggaccccaattcggtggaccgtgcctggtgggacttcttcgccgactacaagccg
ggcgttggcgccgcggctccggcgggtactgcggccgcgggggccgcagccaccaccacc
gctccggccgctcccgccgccccggctgctccgtcggtcccggcgccggccccggccgcc
ccgaagcccgcggccgccgcacccgccgccgcggctccggctccggctgcgaagcccgcc
gcccccgccccggccgcgaagcccgctcagccgaagaaggccgagcccgccgctgccgcc
gacggccccgagctggtcacgctgcgcggccccgccgccgcggtcgcgaagaacatgaac
gcctcgctggaggtgcccacggccacgtccgtgcgcgcggtcccggtgaagctgctcttc
gacaaccgcatcgtcatcaacaaccacctcaagcgcgcccggggcgggaagatctccttc
acgcacctgatcggctacgcgatggtgcaggccatcaaggccatgccatcgatgaactac
tccttcgcggagaaggacggcaagccgaccctggtcaagccggagcacatcaacttcggc
ctcgccatcgacctggtcaagcccaacggcgaacgccagctcgtggtcgcgggcatcaag
aaggccgagaccctgaacttcttcgagttctggcaggcctacgaggacatcgtccgccgc
gcccgcgacggcaagctgggcatggacgacttcaccggcgtgacggtctccctgaccaac
cccggtggcctcggcaccgtccactcggtcccgcgtctgatgcccggccagtcggtgatc
atgggcgtcggctccatggactacccggcggagttccagggcacctcccaggacaccctg
aacaagctcggcatctcgaaggtcatgacgctcacgtcgacctacgaccaccgggtcatc
cagggcgccgcctccggcgagttcctgcggatcgtcgcgaacttcctcctcggcgagggc
aacttctacgacgagatcttcgaggcgctgcgcatcccctacgagccggtccgctggctc
aaggacatcgacgcgtcgcacgacgacgacgtcaccaaggccgcgcgcgtcttcgagctg
atccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctggagtaccgc
cagcgcaagcaccccgacctggacatcaccgagcacggcctcaccctgtgggacctcgag
cgcgagttcgcggtcggcggcttctccggcaagtccctgatgaagctgcgcgacatcctc
ggcgtgctgcgcgactcgtactgccgcaccaccggcatcgagttcatgcacatccaggac
ccgaagcagcgcaagtggatccaggaccgcatcgagcgcgggcacaccaagcccgagcgt
gaggagcagctgcgcatcctgcgccggctgaacgcggcggaggccttcgagaccttcctg
cagaccaagtacgtcggccagaagcgcttctcgctggagggcggcgagtccgtcatcccg
ctgctcgacgccgtgctggactcggccgccgagtcccgcctggacgaggtcgtcatcggc
atggcccaccgcggccgcctgaacgtcctcgccaacatcgtcggcaagtcgtacgcccag
atcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtg
aagtaccacctgggcgccgagggcaccttcaccggcctggacggcgagcagatcaaggtc
tcgctcaccgccaacccctcgcacctggaggcggtggacccggtcctggagggcgtcgcc
cgcgccaagcaggacatcatcaacaagggcggcacggacttcacggtcctgccggtggcc
ctgcacggcgacgcggccttcgcgggccagggcgtggtggccgagaccctgaacatgtcg
cagctgcggggctaccgcaccggcggcacggtccacgtggtcatcaacaaccaggtcggc
ttcacggcggcgccggagtcctcgcgctcgtcgatgtacgccaccgacgtggcccgcatg
atcgaggccccgatcttccacgtgaacggcgacgaccccgaggcggtcgtccgcgttgcc
cgcctggccttcgagttccgccaggcgttcaacaaggacgtcgtgatcgacctcatctgc
taccgccgccgcggtcacaacgagtcggacaacccggccttcacccagccgctgatgtac
gacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctcatcggtcgc
ggcgacatcaccctggaagaggccgagcaggcgctgcaggactaccagggccagctggag
aaggtcttcacggaggtccgcgaggccacctcgcagccggccgccgtggagccctcggac
ccgcaggccgagttcccggtcgccgtcaacacggcggtgaccacggagaccgtcaagcgg
atcgccgagtcccaggtcaacatccccgaccacatcaccgtccacccgcgtctgctgccg
cagctgcagcgccgggcgtcgatggtcgaggacggcaccatcgactggggcatgggcgag
accctcgcgatcggctccctgctgctggagggcgtcccggtccggctggccggccaggac
tcgcagcgcggtacgttcggccagcgtcacgcggtgatcatcgaccgcgagacgggcgag
gagtacacgccgctgcagtacctctccgaggaccaggcgcggctgaacgtctacaactcc
ctgctgtccgagtacgcggccatgggcttcgagtacggctactcgctggcccgccccgac
gcgctcgtgatgtgggaggcgcagttcggcgacttcgtcaacggcgcccagacggtcgtg
gacgagttcatctcgtcggccgagcagaagtgggcccagacctccggcgtcgtcctgctc
ctgccgcacggctacgagggccagggcccggaccactcctcggcccgcccggagcggttc
ctgcagctgtgcgcgcagaacaacatgacggtcgcgatgccgacgtccccggcgaactac
ttccacctcctgcggtggcagtcgcacaacccgcaccacaagccgctggtcgtcttcacc
ccgaagtcgatgctgcgtctgaaggccgcggcctcgaaggcggaggagttcacgagcggc
cagttccagccggtcatcggcgatgcgtcggtcgacccggccgcggtcaagaaggtcgtc
ttctgcgccggcaaggtctactacgacatcgaggccgagcggaagaagcgcggcatcacg
gacacggcgatcatccgcatcgagcgcctgtacccgctgccgggtgccgagctccaggcg
gagatcgccaagtacccgaacgccgagaagtacctgtgggcccaggaggagccggcgaac
cagggtgcgtggccgttcatcgcgctcaacctgatcgaccacctggacctggcggtcggc
gccgaggtcccgcacggcgagcgtctgcggcggatctcccgtccgcacggctcgtccccg
gccgtcggttccgccaagcggcaccaggccgagcaggagcagctggtgcgtgaggtgttc
gaggcctga
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