Streptomyces cyaneofuscatus: R2B67_10100
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Entry
R2B67_10100 CDS
T09646
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scye
Streptomyces cyaneofuscatus
Pathway
scye00020
Citrate cycle (TCA cycle)
scye00630
Glyoxylate and dicarboxylate metabolism
scye00785
Lipoic acid metabolism
scye01100
Metabolic pathways
scye01110
Biosynthesis of secondary metabolites
scye01120
Microbial metabolism in diverse environments
scye01200
Carbon metabolism
scye01210
2-Oxocarboxylic acid metabolism
Module
scye_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scye_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scye00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
R2B67_10100
00630 Glyoxylate and dicarboxylate metabolism
R2B67_10100
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2B67_10100
Enzymes [BR:
scye01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
R2B67_10100
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
R2B67_10100
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
R2B67_10100
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
R2B67_10100
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WOP08893
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Position
2434447..2438271
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AA seq
1274 aa
AA seq
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MSSQSPSNSSISTDQASPGTNPAAAFGANEWLVDEIYQQYLQDPSSVDRAWWDFFADYKP
GSSGTADKPVPGAAASGAAATETPAAAAPAQAAAPATTAAAPAPAKAAPAKAEQAEAKAA
PAPAPAKPAAAKPATAPAKAKPKADDSTEAPAGPEYVTLRGPSAAVAKNMNASLELPTAT
SVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMNYSFAVKDGKP
TLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARIGKLGMD
DFSGVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNKLGISKVM
TLTSTYDHRVIQGAASGEFLRVLSQLLLGQNDFYDEIFKALRIPYEPVRWLTDIDASHDN
DVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLERDFAVGGFA
GKSMMKLRDILGVLRESYCRTTGIEFMHIQDPKQRKWLQDRVERPRTQQPEREEQLRILR
RLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMAHRGRLN
VLANIVGKSYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSH
LEAVDPVLEGIARAKQDIINKGGTDFTVLPIALHGDAAFAGQGVVAETLNMSQLRGYRTG
GTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLAFEFRQ
AFNKDVVIDLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIGRGDITLEEA
EQALQDFQGQLEKVFAEVREATSQPAAPHIPEPQAAFPVAVETAVSAEVVKRIAESQVNI
PESITVHPRLMPQMQRRAASVENGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQ
RHAVLVDQVTGEDYTPLLYLTEDQARYNVYDSLLSEYAAMGFEYGYSLARPESLVIWEAQ
FGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDN
MTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKIEEFTVGGFRPVIGD
DSVKAENVRKVVFVSGKLYYDLDAEREKRGDTETAIIRLERLYPLPGAEIQAEIAKYPNA
EKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRH
QAEQTQLVNEVFEA
NT seq
3825 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagcatctcgaccgaccaagccagcccgggcacc
aacccggccgccgctttcggcgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggatcccagttcggtcgatcgcgcctggtgggacttcttcgccgactacaagccg
ggttcctccggcacggcggacaagcccgttcccggcgccgcagcctcgggggctgcggcg
accgagaccccggccgccgccgcaccggcgcaggccgcggctccggccaccaccgcagcc
gctccggctccggcgaaggcggccccggccaaggccgagcaggccgaggccaaggccgcc
ccggctccggccccggcgaagcccgcggcagcgaagcccgccaccgcgcccgccaaggcc
aagccgaaggccgacgactccaccgaagccccggccggccccgagtacgtgacgctgcgc
ggcccctcggccgccgtcgcgaagaacatgaacgcctcgctggagctgccgacggccacg
tccgtccgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccac
ctcaagcgcgcccgtggcgggaagatctccttcacgcacctcatcgggtacgcgatggtg
caggccctcaaggccatgccgtcgatgaactactccttcgcggtgaaggacggcaagccg
accctggtcaagccggagcacgtcaacctcggtctcgccatcgacctggtgaagccgaac
ggcgaccgccagctggtcgtcgcggccatcaagaaggccgagacgctcaacttcttcgag
ttctggcaggcgtacgaggacatcgtccggcgcgcccgcatcggcaagctcggcatggac
gacttctccggcgtcaccgcctcgctgaccaaccccggcgggatcggcaccgtccactcg
gtgccccgcctgatgcccggacagggcctcatcatgggcgtcggcgcgatggactacccg
gcggagttccagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatg
acgctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctg
cgggtcctgagccagctgctgctcggccagaacgacttctacgacgagatcttcaaggcc
ctgcgcatcccgtacgagccggtccgctggctcacggacatcgacgcgtcgcacgacaac
gacgtgacgaaggccgcgcgggtcttcgagctgatccactcctaccgggtccgcggccac
gtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctcgacatc
accgagcacggcctcaccctgtgggacctggagcgggacttcgcggtcggcgggttcgcc
ggcaagtcgatgatgaagctccgcgacatcctcggcgtgctgcgtgagtcgtactgccgc
accaccggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggctccaggac
cgcgtggagcggccccgcacccagcagcccgagcgcgaggagcagctgcgcatcctgcgc
cggctgaacgcggccgaggcgttcgagacgttcctgcagaccaagtacgtcggtcagaag
cggttctcgctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactcc
gcagccgaggcccgcctcgacgaggtcgtcatcggcatggcccaccgtggccggctgaac
gtgctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaac
ctcgacccgcgctcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggc
accttcaccggtctggacggcgagcagatcaaggtctcgctggccgccaacccctcgcac
ctggaggcggtcgacccggtcctggagggcatcgcccgcgccaagcaggacatcatcaac
aagggcggcacggacttcacggtcctgccgatcgcgctccacggcgacgcggccttcgcg
ggccagggcgtcgtcgccgagacgctcaacatgtcgcagctgcgcggctaccgcaccggc
ggcaccgtgcacgtggtgatcaacaaccaggtcggcttcaccgccgccccggagtcctcg
cgctcctcgatgtacgccaccgacgtggcgcgcatgatcgaggcgccgatcatccacgtc
aacggcgacgacccggaggccgtggtccgcgtcgcgcggctcgccttcgagttccggcag
gcgttcaacaaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgag
ggcgacaacccggagttcaccaaccctcagatgtacaccctgatcgacaagaagcgctcg
gtgcgcaagctctacaccgagtccctcatcggtcgcggcgacatcacgctggaagaggcg
gagcaggcgctccaggacttccagggtcagctggagaaggtcttcgccgaggtccgcgag
gccacctcgcagccggccgccccgcacatcccggagccgcaggccgccttcccggtcgcc
gtggagaccgcggtctccgccgaggtcgtgaagcggatcgccgagtcccaggtcaacatc
cccgagtcgatcaccgtccacccccgtctgatgccgcagatgcagcgtcgcgcggcctcg
gtggagaacggcacgatcgactggggcatgggcgagaccctggccatcggttcgctgctg
atggagggcaccccggtccggctcgccggccaggacagccgccgcggcacgttcggccag
cgccacgcggtgctggtggaccaggtcaccggcgaggactacaccccgctgctgtacctc
accgaggaccaggcccgttacaacgtctacgactcgctgctcagcgagtacgcggcgatg
ggcttcgagtacggctactcgctggcccgcccggagtcgctggtcatctgggaggcccag
ttcggtgacttcgtcaacggcgcccagaccgtcgtggacgagttcatctcctcggccgag
cagaagtggggccagacctccggcgtcacgctgctgctgccgcacggctacgagggccag
ggcccggaccacagctccgcccgccccgagcgcttcctccagatgtgcgcgcaggacaac
atgacggtcgcgatgccgaccctgccgtcgaactacttccacctgctgcgctggcaggtg
cacaacccgcaccacaagccgctgatcgtcttcaccccgaagtcgatgctgcgtctgaag
gccgcggcgtcgaagatcgaggagttcaccgtcggcggcttccgcccggtgatcggcgac
gacagcgtcaaggcggagaacgtccgcaaggtcgtgttcgtctcgggcaagctctactac
gacctggacgccgagcgggagaagcgcggcgacacggagaccgcgatcatcaggctggag
cgcctgtacccgctgccgggtgcggagatccaggccgagatcgccaagtacccgaacgcc
gagaagtacctctgggcccaggaggagccggccaaccagggtgcgtggccgttcatcgcg
ctcaacctgatcgaccacctggacctggccgtcggcgcggacgtgccgcacggcgagcgc
ctgcgccgtatctcgcggccgcacggctcgtccccggcggtcggctcggccaagcgtcac
caggcggagcagacgcagctggtcaacgaggtcttcgaggcctga
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