KEGG   Streptomyces cynarae: N8I84_27800
Entry
N8I84_27800       CDS       T09435                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
scyn  Streptomyces cynarae
Pathway
scyn03030  DNA replication
scyn03410  Base excision repair
scyn03420  Nucleotide excision repair
scyn03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:scyn00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    N8I84_27800 (ligA)
   03410 Base excision repair
    N8I84_27800 (ligA)
   03420 Nucleotide excision repair
    N8I84_27800 (ligA)
   03430 Mismatch repair
    N8I84_27800 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:scyn03032]
    N8I84_27800 (ligA)
   03400 DNA repair and recombination proteins [BR:scyn03400]
    N8I84_27800 (ligA)
Enzymes [BR:scyn01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     N8I84_27800 (ligA)
DNA replication proteins [BR:scyn03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     N8I84_27800 (ligA)
DNA repair and recombination proteins [BR:scyn03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     N8I84_27800 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     N8I84_27800 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     N8I84_27800 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      N8I84_27800 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD Nlig-Ia PTCB-BRCT HHH_5 HHH Zn_ribbon_TFIIB
Other DBs
NCBI-ProteinID: UXY22086
LinkDB
Position
unmamed1:6094625..6096820
AA seq 731 aa
MAGDKQAETTVPAEAREQHAQLAEQIEEHRFRYYVKDAPVISDAEFDRLLRSLEALEDQY
PELRTPDSPTQKVAGAYATEFTAVQHRERMLSLDNAFDDEELAAWADRVAKEVGTSAYHF
LCELKVDGLAVNLTYEQGRLTRAATRGDGRTGEDITPNVRTIAEIPDRLKGDHVPDLVEI
RGEVYFPMEKFEELNARLVGGGDKPFTNPRNAAAGSLRQKDPRITATRPLHMVVHGIGAL
KGFKDGLTRLSEAYDLLKSWGLPTARHNKVVGDLDGVRQFIAYFGENRHSVEHEIDGVVV
KLDEIPLQGRLGSTSRAPRWAIAYKYAPEEVNTKLINIRVGVGRTGRVTPYAQVEPVTVA
GSEVEFATLHNQDVVKAKGVLIGDTVVLRKAGDVIPEILGPVVDLRDGTEREFVMPSECP
ECGTPLRPMKEGDVDLRCPNARSCPAQLRERLFYLAGRKALDIEHFGYVAAAALTQPLEP
SEPPLKDEGDLFDLTVEQLLPIKAYVLDQDSGLPKRDPKTGEEKIVTVFANQQGEPKKNA
LAMLENIAAAKERPLARVLTGLSIRHVGPVAAEALAREFRSIERIDQASEEELAATDGVG
PIIAASLKQWFTEDWHRDIIRKWKAAGVRMEEEGSGEDEGPRPLEGLTVVVTGTLGQYTR
DGAKEALQSRGAKVTGSVSKKTSFVVVGENPGSKYDKAMQLKVPVLDEDGFAVLLERGPE
AAAEVALPTGE
NT seq 2196 nt   +upstreamnt  +downstreamnt
gtggccggcgacaagcaagcggagacgacggtgcccgccgaggcccgggagcagcacgcg
cagctcgccgagcagatcgaggagcaccgcttccggtactacgtgaaggacgctcccgtc
atcagcgacgcggagttcgaccggctcctgcgctccctcgaagcgctagaggaccagtac
ccggagctgcgcacccccgactcgcccacccagaaggtcgcgggggcgtacgcgacggag
ttcacggccgtccagcaccgcgaacgcatgctctccctggacaacgcgttcgacgacgag
gagctcgccgcctgggccgaccgcgtcgccaaggaggtcggcacctccgcgtaccacttc
ctgtgcgagttgaaggtcgacggcctcgcggtcaacctcacttatgagcagggccgcctc
acgcgcgccgccactcgtggcgacggccgaaccggcgaggacatcactccgaacgtccgt
acgatcgcggagatcccggaccgcctcaagggcgaccacgtccccgacctcgtggagatc
cgcggcgaggtctacttcccgatggagaagttcgaggaactcaacgcccgactggtgggg
ggcggcgacaaacccttcaccaacccgcgcaacgcggcggccggttccctgcgccagaag
gacccgcgcatcacggccacccgcccgctgcacatggtggtccacggcatcggcgccctg
aagggcttcaaggacggcctcacgcgcctctccgaggcgtacgacctgctgaagtcctgg
ggcctgcccaccgcccggcacaacaaggtggtcggcgacctcgacggcgtacggcagttc
atcgcctacttcggggagaaccgccactccgtggagcacgagatcgacggagtcgtcgtc
aagctcgacgagatcccgctccagggccgcctcggctccacctcgcgtgccccgcgctgg
gcgatcgcgtacaagtacgcgccggaggaggtcaacaccaagctcatcaacatccgcgtg
ggcgtgggccgtacgggccgggtcacgccgtacgcgcaagtcgagccggtcacggtggcc
ggctcggaggtcgagttcgccaccctgcacaaccaggacgtggtcaaggccaagggcgtg
ctcatcggcgacacggtggtgctgcgcaaggccggtgacgtcatcccggagatcctcggc
ccggtcgtcgacctgcgtgacggcaccgagcgggagttcgtgatgccgtccgagtgcccc
gagtgcggcacaccgcttcggcccatgaaggagggcgacgtcgatctacgttgcccgaac
gcgcgttcctgtcccgctcagttgcgcgagcgtctcttctacctggcgggccgcaaggcg
ctggacatcgaacacttcggatacgtcgccgccgccgccctcacccagcccttggagcct
tccgagccaccgctgaaggacgagggtgacctgttcgacctcaccgtcgaacagctgctg
cccatcaaggcgtacgtcctcgaccaggacagcggcctgcccaagcgcgacccgaagacc
ggcgaggagaagatcgtcacggtcttcgccaaccagcagggcgagccgaagaagaacgcg
ctcgcgatgctggagaacatcgcggccgccaaggagcgtccgctcgcccgcgtcctcacc
ggcctgtcgatccgtcacgtcggcccggtcgcggcggaggcgctggcccgcgagttccgg
tcgatcgaacggatcgaccaggcgagcgaagaggagctggcggccaccgacggggtcggg
cccatcatcgccgcctccctcaagcagtggttcaccgaggactggcaccgcgacatcatc
cgcaagtggaaggctgcgggcgtccgtatggaggaggagggctccggcgaggacgaggga
ccgcgtccgctggaggggctcacggtggtcgtcaccggaacgctcgggcagtacacccgg
gacggcgccaaggaggcgctgcagagtcgtggcgccaaagtgaccggttctgtctccaag
aagacgtccttcgtcgtggtgggggagaatcctgggtcgaagtacgacaaggccatgcag
ctgaaggtccccgtgctggatgaggacggtttcgccgtcctgttggaacgagggccggaa
gcagctgcggaagtcgcgcttccgaccggggagtag

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