Streptomyces sp. CFMR 7: ABE83_03660
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Entry
ABE83_03660 CDS
T04074
Name
(GenBank) squalene-hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
scz
Streptomyces sp. CFMR 7
Pathway
scz00909
Sesquiterpenoid and triterpenoid biosynthesis
scz01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
scz00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
ABE83_03660
Enzymes [BR:
scz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
ABE83_03660
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
ABE83_03660
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Prenyltrans
DUF6894
Motif
Other DBs
NCBI-ProteinID:
ALC26272
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All DBs
Position
complement(965342..967342)
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AA seq
666 aa
AA seq
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MTATTDGPAGAAKLSATTAGHPDRTTPAPDEVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDAPDEPHMARAASWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPARPNPPRKLAPAASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSLIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKATDWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSSFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAQHPRTQRGIEWLLTEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVEWLESVQNDDGGWGEDLRSYREEKWIGHGESTASQTAWALLALLAAGRRDSVAV
SRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAQGV
NT seq
2001 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggacccgccggggccgcgaaactctccgcgaccacggcagga
catcccgaccgcacgacccccgccccggacgaggtgctcgccgccgcgcggcgggccgcc
gaacgctccgtggagcaccttctcggcagacaggacgagcagggctggtggaagggggac
ctcgccaccaacgtcacgatggacgccgaggacctgctcctgcgccagttcctcgggatc
caggacccggagaccacccgggccgccgccctcttcatccggggcgagcaactgggtgac
ggcacctggaacaccttctacggcggaccgagcgacctctccgccaccatcgaggcctat
gtggccctgcggctggccggggacgccccggacgagccgcacatggcccgcgccgcatcc
tggatcagggagcagggcggcatcgcggccgcccgggtcttcacccggatctggctggcg
ctcttcggctggtggaagtgggacgacctccccgaactcccgcccgagctgatgttcctg
ccctcctgggtcccgctcaacatctatgacttcggctgctgggcccgccagaccatcgtc
cctctgaccatcgtctccgcaaagcgccccgtgcggcccgcgcccttcgccctggacgag
ctgcacaccgacccggcccgtcccaacccgcccaggaagcttgccccggcggccagttgg
gacggcctcttccagcgcctggacaaggggctgcacctctaccacaaggtcgccccgcgc
ccgctgcgccggatcgcgatgaacgtggcggcccggtggatcgtcgaacgccaggagaac
gacggctgctggggcggcatccagcccccggccgtctactccctcatcgccctgcatctc
ctcggctacgacctggaccacccggtgatgaaggcgggcctcgcctcgctggaccggttc
gccgtccaccgcgaggacggcgcccggatggtcgaggcctgccagtcgcccgtctgggac
acctgcctggccaccatcgccctggtcgacggcggactcagacccgaccaccccgccctg
gtgaaggccaccgactggatgctggccgaggagatcacccggcccggcgactggtcggta
cgtaaacccgaactcgcccccggaggctgggcgttcgagttccacaacgacaactacccg
gacatcgacgacaccgccgaagtcgtcctggcgctgcgccgggtccgccaccccgacccc
gcccgggtggaggccgccatcgagcgcggggtccgctggaacctcgggatgcagtcccgc
aacggggcctggggcgccttcgacgccgacaacaccagctccttccccaaccgcctgccc
ttctgcgacttcggcgaggtcatcgacccgccgtcggccgatgtcaccggccatgtggtg
gagatgctcgccgtcgaagggcgcgcccaacacccccgtacgcaaaggggtatcgagtgg
ctgctcaccgaacaggaggcgtgcggcgcctggttcgggcgctggggcgtcaactatgtg
tacgggacggggtcggtggtccccgcgctggtggccgccggactgcccgccgcccacccc
tcgatccgccgggcggtggagtggctggagtccgtgcagaacgacgacggcggctggggc
gaggacctgcgctcgtaccgggaggagaagtggatcgggcacggtgagtccaccgcctcc
cagaccgcctgggccctgctcgccctgctggcggccggccgccgcgacagcgtcgccgtc
tcccgcggggtcacctggctgaccgaggcccagcaggccgacggctcctgggacgagccg
tatttcaccggtacgggcttcccctgggacttctccatcaactaccacctctaccgtcag
gtcttccccctcacggcactcgggcgctacgtgtacggcgacccgttcgccgaccgtacg
ggcgccgcccagggcgtctga
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