Streptomyces drozdowiczii: NEH16_23200
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Entry
NEH16_23200 CDS
T09042
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sdrz
Streptomyces drozdowiczii
Pathway
sdrz00010
Glycolysis / Gluconeogenesis
sdrz00020
Citrate cycle (TCA cycle)
sdrz00620
Pyruvate metabolism
sdrz00785
Lipoic acid metabolism
sdrz01100
Metabolic pathways
sdrz01110
Biosynthesis of secondary metabolites
sdrz01120
Microbial metabolism in diverse environments
sdrz01200
Carbon metabolism
sdrz01210
2-Oxocarboxylic acid metabolism
Module
sdrz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sdrz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NEH16_23200 (aceE)
00020 Citrate cycle (TCA cycle)
NEH16_23200 (aceE)
00620 Pyruvate metabolism
NEH16_23200 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NEH16_23200 (aceE)
Enzymes [BR:
sdrz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NEH16_23200 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
UZK56603
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Position
complement(5100847..5103528)
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AA seq
893 aa
AA seq
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MTDPVGKLPSELDQLPDRDPEETAEWAASLDAVTKAAGPHRAAYLMRRSLQHAEGAGLAL
PKLLETDYVNSIPTAAEPDFDGDLEMESKITAWNRWNAAAMVTRGARFGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYVQGHASPGIYARAFLDGRLSEQQLDNFRQESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLANRNIKDTSNSHVWAFLGDGEM
DEPESTAALALAAREKLDNLTFVINCNLQRLDGPVRANFRVVQELEGAFRGAGWNVIKTL
WGNAWDELFQLDTTGALVRRLREVPDAQFQTYATRDVAYIREHFFGAEPALAELAKLLTD
AKIAECFYTSRGGHEARKVYAAYRAAVEHKGAPTVILAQTVKGYTLGKGFESKNANHQMK
KLTIDEFKGMRELLGLPIPDSAFADGLVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
AVALPQPEERAFAALKKGSGKQEMATTMAFVRLVKDLMRDKQTGRRWVPIVPDEARTFGM
ESLFPSAGIYSPLGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGAMADFIAAATSYATH
GETMIPFYIFYSMFGWQRTGDQFWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHLI
AATNPASLNYDPAFAYEIAVIVKDGLRRMYGQAAPGEDSNVFYYLTVYNEPKPQPAMPEG
VEEGIVKGLYRFKEGTPAAADAPRAQLLASGTAIHWALEAQELLAADWGVTADVWSATSW
GELRREALECDEALLRGEQRVPYVTQALEGAPGPVVAVSDWMRAVPDQISQWVEQDYTSL
GTDGFGLSDTRDAARRHFGVDAPSVVVATLAQLARRGEVPATAVKEARDRYGL
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccgtaggaaagcttccgagcgagctcgaccagctcccggaccgcgacccg
gaggagaccgctgaatgggcggcctccctggatgccgtcaccaaggccgcgggcccgcac
cgtgccgcgtacctgatgcggcgctcgctccagcacgccgagggcgccggtctcgcgctg
cccaagctgctggagaccgattacgtcaactccatcccgaccgccgcggagcccgacttc
gacggtgacctggagatggagtcgaagatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacccgtggcgcgcgcttcggcgtcggcggccacatcgccaccttcgcctcggcg
gcctggctgtacgagaccggcttcaaccacttcttccgcggcaaggagggggacggctcc
ggcgaccagctgtacgtgcagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggctcagcgagcagcagctcgacaacttccgccaggagtccggcggcaacggc
ctgccctcctacccgcacccgcgccggctgccctggctgtgggagttccccacggtctcc
atgggcctcggcccgctctcggcgatctaccaggcgcgcttcaaccgctacctcgccaac
cgcaacatcaaggacacgtcgaactcgcacgtctgggccttcctgggcgacggcgagatg
gacgagcccgagtcgaccgccgccctcgccctcgcggcccgcgagaagctcgacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggtccggtccgcgccaacttccgc
gtcgtgcaggagctggagggcgccttccggggcgccggctggaacgtcatcaagacgctc
tggggcaacgcctgggacgagctgttccagctcgacaccacgggcgcgctggtccgccgc
ctccgcgaggtcccggacgcgcagttccagacgtacgccacccgcgacgtcgcctacatc
cgcgagcacttcttcggcgccgagcccgccctcgccgagctggcgaaactgctcaccgac
gcgaagatcgccgagtgcttctacacctcgcgcggcggccacgaggcccgcaaggtgtac
gcggcgtaccgcgcggccgtcgagcacaagggcgcgccgaccgtgatcctcgcccagacg
gtgaagggctacacgctcggcaagggcttcgagtccaagaacgccaaccaccagatgaag
aagctgacgatcgacgagttcaagggcatgcgcgagctgctcggcctcccgatcccggac
agcgccttcgccgacggcctggtgccctacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgccgccctcggcggccccgccccggcccgccgggtgcac
gcggtggcgctgccgcagcccgaggagcgcgcgttcgccgcgctcaagaagggctccggc
aagcaggagatggccaccaccatggccttcgtccgcctggtcaaggacctgatgcgggac
aagcagaccggcaggcgctgggtgccgatcgtccccgacgaggcccgcaccttcggcatg
gagtcgctgttcccctcggccggcatctactcgccgctgggccagacgtacgagccggtc
gaccgcgaccagctgatgtactacaaggaggccaaggacggccagatcctcaacgagggg
atcaccgaggccggcgccatggccgacttcatcgccgccgccacgtcgtacgcgacgcac
ggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcggacgggc
gaccagttctggcagctcgccgaccagctcggcaagggcttcatcgtcggcgccaccgcc
ggccgtacgaccctgacgggcgagggcctccagcacgcggacggccactcgcacctgatc
gccgccacgaacccggcgtcgctcaactacgacccggcgttcgcgtacgagatcgcggtg
atcgtcaaggacggtctgcggcggatgtacggccaggccgcccccggcgaggactcgaac
gtcttctactacctgacggtctacaacgagccgaagccgcagcccgcgatgccggagggc
gtcgaggagggcatcgtcaagggcctgtaccgcttcaaggagggcacgcccgcagcggcg
gacgcgccgcgcgcccagctgctggcctccggcacggcgatccactgggccctggaggcc
caggagctgctggccgccgactggggtgtcacggccgacgtctggtccgcgacctcctgg
ggcgagctgcgccgcgaggcgctggagtgcgacgaggcgctgctccgcggtgagcagcgg
gtgccgtacgtgacgcaggcgctggagggcgctccgggtccggtcgtcgcggtcagcgac
tggatgcgcgcggtgccggaccagatcagccagtgggtggagcaggactacacctcgctc
ggcacggacggcttcggcctctccgacacgcgtgacgcggcccgccgccacttcggcgtc
gacgccccgtccgtcgtggtcgccacgctggcccagctggcccggcgcggcgaggtgccg
gcgaccgccgtcaaggaggcgcgggaccggtacggtctctga
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